Chemistry In Context
9th Edition
ISBN: 9781259638145
Author: Fahlman, Bradley D., Purvis-roberts, Kathleen, Kirk, John S., Bentley, Anne K., Daubenmire, Patrick L., ELLIS, Jamie P., Mury, Michael T., American Chemical Society
Publisher: Mcgraw-hill Education,
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 12, Problem 47Q
Interpretation Introduction
Interpretation:
A brief report about the way in which the method of preparing sitagliptin using of enzymes has to be written by citing the source
Concept Introduction:
Drugs: Drugs are molecules which are taken from an external source to change the normal functioning of the body. The action of drug is in molecular level and the design of many drugs are in such a way that it mimics a particular neurotransmitter or hormone. Drugs bind with receptors showing an increased or decreased effect.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
1.What makes ionic bonds different from covalent bonds? Explain with respect to the bond formation between MgCl2 and N2.
2. A group of young researchers was working on a biochemical pathway. At that time, they produced an enzyme having altered active site. Do you think, the activity of the new enzyme would differ from the original one? Why? On a different reaction they found, an enzyme works best at a temperature near about 30 degree Celsius. At 60 degree Celsius, the enzyme becomes inactivated. Briefly explain, why that enzyme is not working at elevated temperature?
what is a reason why company leaders would add melamine to their product to make the protein content appear higher than the actual amount of the product?
Describe two possible reasons for why food safety inspectors often use an overall nitrogen content test, instead of Bradford assay, to determine the protein content in a product.
You ask the individual if they are taking any non-prescription drugs. They tell you they recently started taking a coenzyme Q10 supplement based on a recommendation from a friend. The structure of coenzyme Q10 is shown below. Looking at the structure of the molecule, which one of the 4 major classes of macromolecules (carbohydrate, lipid, proteins or nucleotides) does it most closely resemble? Be sure to include specific chemical characteristics that support this decision.
Chapter 12 Solutions
Chemistry In Context
Ch. 12.1 - Skill Building Finding Equilibrium Glucose and...Ch. 12.1 - Prob. 12.3YTCh. 12.1 - Prob. 12.4YTCh. 12.2 - Prob. 12.5YTCh. 12.2 - Prob. 12.6YTCh. 12.2 - A practicing scientist must Judge a potential...Ch. 12.3 - Prob. 12.8YTCh. 12.3 - Skill Building Checking on Carbon a. Examine the...Ch. 12.3 - Prob. 12.10YTCh. 12.3 - Prob. 12.11YT
Ch. 12.3 - Prob. 12.12YTCh. 12.4 - Prob. 12.13YTCh. 12.4 - Skill Building Functional Groups in Dopamine Draw...Ch. 12.4 - Prob. 12.15YTCh. 12.5 - Prob. 12.16YTCh. 12.5 - Prob. 12.17YTCh. 12.6 - Prob. 12.18YTCh. 12.6 - Prob. 12.19YTCh. 12.6 - The structures of proteins, such as the ones shown...Ch. 12.7 - Reconsider your work in past chapters. List three...Ch. 12.7 - Prob. 12.22YTCh. 12.7 - Prob. 12.23YTCh. 12.8 - Prob. 12.24YTCh. 12.8 - Prob. 12.25YTCh. 12.9 - Skill Building Ester Formation Draw structural...Ch. 12.9 - Prob. 12.27YTCh. 12.9 - You Decide Supersize My Aspirin A friend who...Ch. 12.9 - Modern methods of drug discovery involve...Ch. 12.10 - Make two lists of drugs for each of the two...Ch. 12.10 - See for yourself the shapes of drug molecules by...Ch. 12.10 - Prob. 12.33YTCh. 12.10 - Prob. 12.34YTCh. 12 - Scientific Practices Follow the Hormone Using the...Ch. 12 - The field of chemistry has many sub-disciplines....Ch. 12 - Prob. 2QCh. 12 - Prob. 4QCh. 12 - Nitrous acid (HNO2) has a Ka value of 4.0 10 4,...Ch. 12 - Use the Henderson-Hasselbalch equation and Table...Ch. 12 - Write the structural formula and line-angle...Ch. 12 - Prob. 8QCh. 12 - Prob. 9QCh. 12 - Prob. 10QCh. 12 - Prob. 11QCh. 12 - Prob. 12QCh. 12 - Estradiol is relatively insoluble in water but...Ch. 12 - Prob. 14QCh. 12 - Prob. 15QCh. 12 - Prob. 16QCh. 12 - Define and relate the two terms: hormone and...Ch. 12 - Refer to Figure 11.17. Select two examples of...Ch. 12 - Prob. 19QCh. 12 - Molecules as diverse as cholesterol, sex hormones,...Ch. 12 - Prob. 21QCh. 12 - Prob. 22QCh. 12 - Prob. 23QCh. 12 - Sulfanilamide is the simplest sulfa drug, a type...Ch. 12 - Explain why an equilibrium constant cannot tell...Ch. 12 - Use the information in Table 12.1 to redraw Figure...Ch. 12 - Draw structural formulas for each of these...Ch. 12 - In Your Turn 12.12, you were asked to draw...Ch. 12 - Prob. 29QCh. 12 - Prob. 30QCh. 12 - Prob. 31QCh. 12 - Prob. 32QCh. 12 - Prob. 34QCh. 12 - Prob. 35QCh. 12 - Prob. 36QCh. 12 - Prob. 37QCh. 12 - Prob. 38QCh. 12 - The text states that some racemic mixtures contain...Ch. 12 - Prob. 40QCh. 12 - Prob. 41QCh. 12 - Prob. 44QCh. 12 - Prob. 47QCh. 12 - Prob. 49QCh. 12 - Dorothy Crowfoot Hodgkin first determined the...Ch. 12 - Prob. 52Q
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- I. Enzymes are globular proteins II. Enzymes react with specific substrate. III. Enzymes are biodegradable substances. O All statements are correct O All statements are wrong O Statements I & II are correct. O Statements I & III are correct O Statemnets II & III are correct Dietary proteins yield amino acids and are deposited in the nitrogen pool. O True O Falsearrow_forwardPlease explain these problems. They are interconnected to each other. A clear explanation is greatly appreciated. Thanks!arrow_forwardthe analysis of a mixture of hydrocarbon cracking products, all of which are able to be distilled, but distillation is unable to separate them cleanly. A. a pharmaceutical product containing 2 stereoisomers of the active ingredient, both of which are fairly polar, aromatic, water soluble, and decompose rather than boil. B. C. The separation of a mixture of water-soluble globular proteins of various sizes. The analysis of a mixture of reactor gases that includes methane, hydrogen, carbon dioxide, carbon monoxide, and nitrogen. D.arrow_forward
- You're an undercover biological weapons agent who has been given an unknown liquid - you suspect that it is just sugar water (because you drank some by accident - you know you're not supposed to have food or drink in the lab, but you do it all the time, and it tasted sweet - plus you didn't die!) One of the tests you need to run is to see if it contains protein (remember, foreign proteins can cause severe immune responses which can be a powerful biological weapon). You set up 3 test tubes each with 10mL of the following: distilled water, gelatin solution and the unknown. The distilled water is clear, the gelatin solution is clear with a beige tint, and the unknown is clear. You use Biuret's Reagent - a dark blue dye which will turn a liquid sample purple in the presence of protein. 1. When Biuret's Reagen is added to the unknown, predict what color you expect it to become if the unknown is just sugar water: [a] (no change | blue | purple). 2.You included both a positive and negative…arrow_forwardFor years we’ve been told that eating fat will cause various health problems and have been warned to eliminate it from our diet. But now we know that not all fat is the same. By understanding the difference between good and bad fats and how to include more healthy fat in your diet, you can improve your mood, boost your energy and well-being, and even lose weight. Since fat is an important part of a healthy diet, rather than adopting a low-fat diet, it’s more important to focus on eating more beneficial “good” fats and limiting harmful “bad” fats. What is their experience with the health risks associated with ‘bad fat’ intake for example obesity, diabetes, heart disease, strokes, cancer, etc.? Why is eating healthy so important? What are are recommendations for maintaining a healthy diet of ‘good fats’? What's the deal with fats?arrow_forwardPAP Chemistry-2903012-42100P-1/ Le Chatelier's Principle/ Lesson 128 2. Zinc (Zn) granules react slowly with dilute hydrochloric acid (HCI), but much faster if the acid is concentrated. Zn(s) 2HCI(aq)ZnCl2(aq) + H2(g) Zinc + Hydrochloric Acid Zinc Chloride + Hydrogen What causes the reaction to proceed faster with concentrated acid? The concentrated hydrochloric acid causes more hydrogen gas to be produced. The pressure of hydrogen gas molecules increases as concentration increases. The concentrated hydrochloric acid molecules move faster than in dilute acid. There are more collisions between the zinc and concentrated hydrochloric acid. PREVIOUarrow_forward
- Enzymes function most efficiently at the temperature of a typical cell, which is 37 degrees Celsius. Increases or decreases in temperature can significantly lower the reaction rate. What does this suggest about the importance of temperature-regulating mechanisms in organisms? How does this translate to the development of enzyme assays for clinical laboratory testing equipment? Explain.arrow_forwardEnzyme b. Binding: Electrostatic Forces Substrates bind to receptors and enzymes through non-covalent interactions (intermolecular forces – IMF). Below is a cartoon of a part of a ligand or substrate interacting with an enzyme (blue line). There are two aspartic acid side chains of the enzyme that are interacting with the substrate (dashed lines). Identify the intermolecular forces. OH R Asp 125 -4----* H-o Asp25 Enzyme Active Sitearrow_forwardBased on a grade 11 chemistry student, answer the following question based on the provided tables: Part G: Final Identification of the Poison By this time, Tylenol has been pulled off the shelves at all of the stores in the area and a nationwide recall has been announced. Several suspicious capsules have been found and tested. The contents of the capsules contain a compound with a nitrogen content of greater than 15% and a carbon content of less than 50%. What is the poison in the capsule? Provide calculations to support your answer.arrow_forward
- ENZYME CATALYSIS-lab ENZYME CONCENTRATION What chemical reaction is being catalyzed in the experiment? Label the substrate(s), enzyme, and product(s).arrow_forwardDescribe the difference between graphs showing temperature versus reaction rate for an enzyme-catalyzed reaction and an uncatalyzed reaction.arrow_forwardWhy are enzymes that are used for laboratory or clinical work stored in refrigerators?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Introductory Chemistry: An Active Learning Approa...ChemistryISBN:9781305079250Author:Mark S. Cracolice, Ed PetersPublisher:Cengage LearningChemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage LearningChemistry: Matter and ChangeChemistryISBN:9780078746376Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl WistromPublisher:Glencoe/McGraw-Hill School Pub Co
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage LearningWorld of ChemistryChemistryISBN:9780618562763Author:Steven S. ZumdahlPublisher:Houghton Mifflin College Div
Introductory Chemistry: An Active Learning Approa...
Chemistry
ISBN:9781305079250
Author:Mark S. Cracolice, Ed Peters
Publisher:Cengage Learning
Chemistry for Today: General, Organic, and Bioche...
Chemistry
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Cengage Learning
Chemistry: Matter and Change
Chemistry
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Glencoe/McGraw-Hill School Pub Co
Organic Chemistry
Chemistry
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:Cengage Learning
World of Chemistry
Chemistry
ISBN:9780618562763
Author:Steven S. Zumdahl
Publisher:Houghton Mifflin College Div
Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY