Which of these epigenetic changes could lead to reduced transcriptlon gene? Please make sure to select all correct answer options. O decreasing acetylation of histones associated with the nucleosomes of that gene O inducing histone modifications that allow the formation of denser nucleosomes in the regulatory region of the gene O increasing acetylation of histones associated with the nucleosomes of that gene O repositioning the nucleosomes associated to the gene to expose the enhancer and promoter DNA of the gene

Q: What is the substrate of a histone acetyltransferase?

A: Substrate are molecule on which an enzyme acts.  Transcription is the process by which information…

Q: gene transcription regulation in eukaryotes that are post-transcriptional/pre-translational:

A:

Q: A researcher found that she could increase phosphorylation of amino acids adjacent to methylated…

A: Histone Phosphorylation It is associated with transcriptional activation.  It takes place with the…

Q: Understanding why these receptors are present when they are not supposed to be is important in…

A: When there is methylation at the cytosines present in promoter the genes are silenced as they blocks…

Q: transcriptional repressor leading to decreased gene expression. a. chromatin remodelling complex…

A: Transcriptional repressors are the molecules that block/inhibit gene expression. They directly act…

Q: D D Intron +1 E E A В В C GGGCGG GCCCAATCT TATAAA Intron -5000 -100 -25 1. What region functions…

A: The transcription is the process of conversion DNA to RNA . DNA stands for dioxy ribonucleic acid…

Q: Explain how transcription regulators in eukaryotic cells are able to act at a great distance from…

A: DNA is a nucleic acid present in the nucleus of the eukaryotic cells.

Q: In response to potentially toxic substances (e.g., high levels of iron), eukaryotic cells often use…

A: Post-transcriptional modifications of pre-mRNA molecules like capping, splicing, and…

Q: This question is regarding the 6 areas that can be involved in the control of gen expression: Part 1…

A: Gene expression is the transcription of a gene into mRNA and its subsequent translation into…

Q: Lactose intolerant individuals do not produce the enzyme lactase. Studies show that the gene that…

A: Lactose sugar is obtained from milk products and milk. When people do not produce enough lactase…

Q: Cancer cells removed from a patient's tumor have increased gene expression of several hundred genes…

A: Cancer  Cancer if a kind of disorder which caused by several means like drug, radiation, malfunction…

Q: Histone methylation can have many different effects on gene expression. In some cases, histone…

A: Expression of gene is highly under control by various mechanisms such as histone modification which…

Q: E27. A cloned gene fragment contains a regulatory element that is recog- nized by a regulatory…

A: Electrophoretic mobility shift assay is used to study the protein and DNA interaction i.e it detects…

Q: What event in eukaryotes serves as the "trigger" for entering the elongation phase of transcription…

A: Transcription occurs in the three steps—initiation, elongation, and termination. The elongation…

Q: Select the answer that correctly expresses a valid comparison between transcriptional regulation in…

A: Transcriptional regulation is far more complex in eukaryotes than in prokaryotes. Prokaryotic…

Q: You are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate…

A: Genes are the fundamental unit of heredity. They store genetic information in the form of DNA, which…

Q: Histone modifying enzymes can be over- or under-expressed in a variety of human diseases and…

A: According to guidelines we have to answer the first question only. so please kindly post the…

Q: silence genes

A: Gene silencing is a mechanism that regulates gene expression to define cell fate and also regulates…

Q: You are teaching a class on the regulation of eukaryotic gene expression. such as the promoter…

A: Binding of RNA polymerase II  and transcription factors is necessary for transcription.

Q: Compared to heterochromatin, euchromatin is O comprised of densely packed nucleosomes and with…

A: Heterochromatin is characterized as the region of the chromosome which is obscurely darkled stained…

Q: Select the following descriptions of gene transcription regulation in eukaryotes that are…

A: * Post translational modification are covalent and enzymatic modifications of proteins that follows…

Q: Enzymes that acetylate the e-amino group of lysine in the histone tails are called and are involved…

A: Histone is made up of majority lysine and arginine (positive amino acids) as a result negative…

Q: Match the given step with the major central dogma event being referred to. The U2 snRNP binds to the…

A:

Q: How does chemical modification of the histones lead to changes in chromatin structure? Choose all…

A: Chromatin It refers to the complex of DNA and proteins that forms chromosomes in the nucleus of…

Q: In a mutant mouse, it was discovered that a gene "W" is moved from its original chromosomal locus to…

A: Introduction  A mutation is a change in the structure of a gene, which is the fundamental unit of…

Q: Match each of the following eukaryotic gene regulatory mechanisms or component to it's best…

A: Long strands of DNA wrap around an octamer of regulatory proteins known as histones: H2A, H2B, H3,…

Q: A drug called garcinol, is isolated from Garciniaindica (a fruit-bearing tree commonly known as…

A: Garcinol is a benzophenone derivative that has been polyisoprenylated. It has phenolic hydroxyl…

Q: An old genetic observation is that a normally active gene will be silenced if it is moved by…

A: Histone alterations are linked to different transcription stages and functions, and epigenetic…

Q: From the list given - choose all the regulatory sequences that you think would control the…

A: A regulatory sequence is a nucleic acid molecule segment that has the ability to increase or…

Q: In Figure 12-26, provide a biochemical mechanism forwhy HP-1 can bind to the DNA only on the left…

A: The family of heterochromatin protein 1 (HP-1) consists of highly conserved proteins which perform…

Q: Nucleosome positioning could affect the transcriptional activity of a gene.

A: Packaging of eukaryotic genomes into chromatin affects every process that occurs on DNA. The…

Q: The use of embryonic stem cells has been proposed for replacing cells that are destroyed by disease…

A: Introduction  Life starts from a single celled-stage termed as Zygote which develop from the fusion…

Q: asic amino acids including lysine. DNA and histones collectively form chromatin. Open open and…

A: Histones can be defined as the family of basic proteins that are associated with the DNA in the…

Q: Which of the following proteins is a combinatorial transcriptional regulator in Drosophila that…

A: There are few important points : Combinatorial transcriptional regulator : It is a particular…

Q: Choose the correct statements about epigenetic regulation in eukarya Group of answer choices…

A: Epigenetic modification regulate the the expression of specific genes within the eukaryotic cells.…

Q: You are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate…

A:

Q: What is the result when the core histones are acetylated via histone acetyltransferase? O A) The…

A: Answer :- Option (B) is correct. - The DNA becomes more tightly associated with the core.

Q: Human growth hormone (hGH) activates expression of the PIND gene in NIH3T3 cells by inducing binding…

A: The hGH (human growth hormone) act as a transcription factor in NIH3T3 cells. It activates the…

Q: HOw does dimerization of transcriptional regulators Increase their specITICity for target DNA…

A: Transcription Factors -- Transcription factors are integrated multiple signal transduction pathways…

Q: Refer to the following illustration to answer the question. O protein A is not made because it is…

A: There are some substances (protein, carbohydrate etc) which regulates the expression of genes. For…

Q: (True/False) There is no redundancy in enzymes that catalyze histone modifications, meaning that an…

A: NOTE- Since you have posted multiple questions, we will be solving the first two questions as…

Q: The following logo plot represents the preferred cis-regulatory sequences (i.e. transcription factor…

A: JASPAR is an open-access database of curated. It is a non-redundant transcription factor (TF) which…

Q: A drug called garcinol, isolated from Garcinia indica (a fruitbearing tree commonly known as kokum),…

A: Garcinol is a polyisoprenylated benzophenone derivative. It contains phenolic hydroxyl groups as…

Q: Which is the expected outcome following the deacetylation of histones?

A: Ans - a) Coiling of chromatin, preventing it from being accessed by the transcriptional machinery.…

Q: ccording to the histone-code hypothesis, what is one way that cell specialization occurs? a)…

A: Histone code hypothesis : It was proposed by Strahl and Allis . Multiple histone modifications ,…

Q: Flowering Locus C (FLC) is a gene that is responsible for flowering in certain plants. FLC is…

A: Acetylation of histones is known to increase the expression of genes through transcription…

Q: Recently, scientists constructed a transgene that expresses a mutant form of Drosophila histone H3…

A: Histones are the alkaline proteins present in the nucleus of the eukaryotic cells. They remain bound…

Q: Examine the network motifs in Figure Q8–5.Decide which ones are negative feedback loops and whichare…

A: Introduction  Protein is the key biomolecule in the biological system, any important physiological…

Q: Q. Both histone deacetylase (HDAC) and Xist would be on a list of genes involved in X chromosome…

A: Histone proteins have positively charged amino acid residues like lysine, arginine. DNA is double…

Q: In a mutant mouse, it was discovered that a gene "W" is moved from its original chromosomal locus to…

A: Answer- Option C -reduced in the mutant mouse than in the wild-type mouse.