Q: Describe the difference between a transcriptional fusion and a translational reporter gene fusion.…
A: Transcription fusion means cloning the promoter of interest, upstream of any transcription unit,…
Q: Exons 1, 2 and 3 of a human gene are 156, 224 and 524 bp long respectively. The introns 1 and 2 are…
A: Introduction :- Exons are the coding regions of an RNA transcript or the DNA that codes for it that…
Q: Write a hypothetical sequence of bases that might be found in the first 20 nucleotides of a promoter…
A: The promoter is a DNA sequence that initiates transcription along with certain proteins. The…
Q: Which of these epigenetic changes could lead to reduced transcriptlon gene? Please make sure to…
A: Epigenetics is the study of changes in organisms produced by changes in gene expression rather than…
Q: complex process, you decide to draw for the class a typical eukaryotic gene/transcription unit with…
A: PPE stands for a promoter-proximal element which is an additional promoter that contains AT-rich…
Q: Which of the following is a property or characteristic of eukaryotic promoters? O They contain the…
A: Promoters in transcription are actually certain specific sequences of DNA that define the starting…
Q: The insertion of transposable elements into genes can alter the normal pattern of expression. In the…
A: NOTE:- As you have posted multiple questions under one, we will solve the first part for you, to…
Q: Below is a diagram of a gene that is not normally alternatively spliced. All four exons (represented…
A: Point mutation refers to any change in a single nucleotide of a gene.
Q: Glenn Croston and his colleagues studied the relation between chromatin structure and transcription…
A: Glenn Croston with his colleagues measured the level of invitro transcription of the gene in a…
Q: Eukaryotic transcription A. is independent of the presence of upstream consensus sequences. B.…
A: Eukaryotic transcription is the intricate process used by the eukaryotic cells to duplicate the…
Q: A genon wide analyst of human genome indicated that approximately 1500 genes encoded transcription…
A: Transcription factors These are proteins that are involved in the process of transcribing the…
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A: Expression of gene is highly under control by various mechanisms such as histone modification which…
Q: E27. A cloned gene fragment contains a regulatory element that is recog- nized by a regulatory…
A: Electrophoretic mobility shift assay is used to study the protein and DNA interaction i.e it detects…
Q: Below is a diagram of a gene that is not normally alternatively spliced. All four exons (represented…
A: Transcription is the synthesis of mRNA from the DNA. Northern blotting is used to study the mRNA and…
Q: You are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate…
A: Genes are the fundamental unit of heredity. They store genetic information in the form of DNA, which…
Q: Regarding the process of gene transcription in eukaryotes, it is correct to state that A)The…
A: Transcription is a process of copying a DNA segment into RNA.
Q: 5
A: The correct answer is A.
Q: You are teaching a class on the regulation of eukaryotic gene expression. such as the promoter…
A: Binding of RNA polymerase II and transcription factors is necessary for transcription.
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Q: A bacterial species has a hypothetical sigma promoter that has the following sequence: TTGGCA -…
A: Promoters are essential components of expression vectors because they regulate RNA polymerase…
Q: Name and discuss two transcription regulatory elements that can be found in the figure. (6) 4.2.…
A: RNA polymerase is a main enzyme responsible for the the transcription of RNA by coding complementary…
Q: You made four mutants for a promoter sequence in DNA and studied them for transcription. The results…
A: Promoter are the sequence present in the DNA. These allow the binding of transcription factor and…
Q: In a couple of sentences, explain how eukaryotic activator proteins (that are usually gene-specific…
A: Transcription factors are proteins that bind to neighbouring DNA and help switch particular genes…
Q: Compare the control of gene regulation in eukaryotes and prokaryotes at the level of initiation of…
A: Since you have posted a question with multiple sub-parts, we will solve the first three subparts for…
Q: You obtain the sequence of a gene containing 10 exons, 9 introns, and a 3'-UTR containing a…
A: A gene is a stretch of nucleotides present on a chromosome. It is the region that encodes the…
Q: Imagine you are going to label a gene associated with apoptosis in Symbiodiniaceae with a Yellow…
A: Splicing is the post transcriptional modification where intron (non coding part of gene) will be…
Q: In any experiment, controls are essential in order to determine the specific effect of changing some…
A: Controls are used in the experiment to analyze the obtained results and reach a conclusion on…
Q: w is the diagram of a eukaryotic gene that encodes a protein. The promoter and n start sites are…
A: Post transcriptional modification removes introns and add existing exons together in the primary RNA…
Q: Eukaryotes can control transcription by three overall type of process, they are ( selection from…
A: The regulation of transcription is more complex in eukaryotes as compared to prokaryotes. This…
Q: A human gene was initially identified as having three exons and two introns. The exons are 456, 224,…
A: Part A.
Q: Choose all of the following that you think are correct Protein(s) that play a role in initiating…
A:
Q: A disease is caused by having no functional protein produced from the KIP gene. An individual has…
A: The gene expression follow the rules of central dogma that involves production of the final product…
Q: Answer these questions concerning promoters. a) What role do promoters play in transcription? b)…
A: A region in DNA molecule that initiates transcription of a particular gene is referred to as a…
Q: Which of the following characteristics is typical of a eukaryotic gene that can be transcribed? a.…
A: A cell is a basic membrane-bound unit and it is often called the basic building blocks of all living…
Q: Examination of the histone modifications around a gene reveals an abundance of histone H3 with…
A: This gene is likely activated since the mono-methylation of the Lysine residue at position 27 in…
Q: Human growth hormone (hGH) activates expression of the PIND gene in NIH3T3 cells by inducing binding…
A: The hGH (human growth hormone) act as a transcription factor in NIH3T3 cells. It activates the…
Q: Explain five ways that eukaryotic gene regulation is more complex than bacterial gene regulation?
A: Prokaryotes and eukaryotes differ in number of ways. We all are aware of this fact that eukaryotes…
Q: Shown below are different regions of an eukaryotic gene. Which of the above regions of a gene will…
A: Transcription is the process by which the information in a strand of DNA is copied into a new…
Q: The sigma factor protein's role in transcription in E. coli includes which of the following?…
A: Sigma factors are subunits of RNA polymerase in bacteria. They control synthesis of RNA intitiation.…
Q: help
A: The copying of the template DNA on the mRNA is called transcription. The formation of mRNA is…
Q: Which of the following parts of the eukaryotic promoter are bound by general transcription factors?…
A: As visible In image GTF general transcription factor bind to core protein , proximal elements
Q: Which is the expected outcome following the deacetylation of histones?
A: Ans - a) Coiling of chromatin, preventing it from being accessed by the transcriptional machinery.…
Q: e given below characteristics which are typical of a eukaryotic gene that can be transcribed? 1.…
A: The fundamental membrane-bound unit known as a cell is frequently referred to as the foundation of…
Q: Which of these epigenetic changes could lead to reduced transcription of a particular gene? Please…
A: Gene expression is predominantly regulated at the transcriptional level, owing to protein binding to…
Q: Choose the item in column 2 that best matches each item in column 1. A. Provides information for…
A: core RNA polymerase - multi subunit enzyme composed of 5 subunits : 2α , β , β' and omega. RNA…
Q: Are the 5′ untranslated regions (5′ UTR) of eukaryotic mRNAs encoded by sequences in the promoter,…
A: The 5′ UTR is located in the first exon of the gene.
Q: A high rate of transcription initiation from promoters in bacteria can be achieved by which of the…
A: Transcription can be described as a process by which the information in a strand of DNA is copied…
Q: Many promoter regions contain CAAT boxes containing consensus sequences CAAT or CCAAT approximately…
A: There are many different non-coding sequences in the DNA (deoxyribonucleic acid) that help in…
Q: The human rhodopsin gene is 2675 nucleotides long from transcription start site to transcription…
A: Throughout an organism's life, the original DNA (deoxyribonucleic acid) molecule in the nucleus acts…
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
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- What effect would inhibitors of histone deacetylases have upon transcription? Group of answer choices They would increase transcription by making the chromatin more compact They would increase transcription by making the chromatin less compact They would decrease transcription by making the chromatin more compact They would decrease transcription by making the chromatin less compact For this question, we will consider a eukaryotic mRNA that has four exons (E1, E2, E3, E4) and three introns (I1, I2, I3). What could occur if a protein were to bind over the 3' splice site of intron 2 (I2)? Group of answer choices The processed mRNA would consist of: E1+E2+E3+E4 The processed mRNA would consist only of: E1+E3 The processed mRNA would consist only of: E3+E4 The processed mRNA would consist of: E1+E2+E4You are teaching a class on the regulation of eukaryotic gene expression. such as the promoter regions, where the RNA polymerase II and transcription factors would bind THERE ARE MULTIPLE ANSWERS THAT YOU CAN CHOOSE From the list given - choose all components that you think are part of a typical eukaryotic gene Group of answer choices A core promoter B 3'UTR C introns D enhancer E coding sequence F mediator protein G PPE H exons I DNA-bending protein J 5'UTRYou are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate this complex process, you decide to draw for the class a typical eukaryotic gene/transcription unit with its major regions, such as the promoter regions, where the RNA polymerase II and transcription factors would bind From the list given - choose all components that you think are part of a typical eukaryotic gene From the list given - choose all the regulatory sequences that you think would control the expression of this eukaryotic gene From the list given - choose all of the regulatory proteins that would bind the eukaryotic gene to control its expression
- 5 5 S 6 5 5 5 6 U 6 U 6 5:14 PM | 0.2KB/s HHHHH R R U RUUR ARU AP AP R U U R R AP R R R AP MOLECULAR...GENETICS. Describe gene regulation at transcription level. Explain the role of antsense RNA in control mechanism. Describe translational control mechanisms. Describe common DNA damages. Distinguish excision and mismatch repair. Describe the role of recA protein in recombination repair Elaborate on SOS repair mechanism. Define thymine dimer. How are they formed and repaired? Describe the molecular basis of mutation. 11 Leu+ Met+ Arg+ Write a detailed note on spontaneous mutation. Explain about mutant detection methods. Define reverse mutation. Describe the mechanism underlying Intragenic and intergenic suppressor mutations Describe the transposition mechanisms. 13 Vo LTE UNIT IV Time (Min) Describe the process of generalised transformation occurring in bacterial chromosome and plasmid. Elaborate on molecular mechanism and significance of transformation 22 Describe the process of…Transcription factors function in the nucleus. However, like (almost) all eukaryotic proteins,they are translated in the cytosol. Can you draw a visual to explain how transcription factor proteinsenter the nucleus from the cytoplasm? Can you also include a representation of relevant proteins and proteindomains to explain how these proteins reach their destination. Thank youPoint mutations in multiple tumor suppressor proteins have been linked to cancer. For example changes in the gene for adenomatous-polyposis-coli protein (APC gene) may result in colorectal cancer. Consider the following DNA sense strand. 3'-TAC CGG TTG TGA AGC TGA ATC-5' (i) (ii) (iii) (iv) Derive the mRNA molecule from the given DNA strand sequence above, paying attention to the polarity of the molecule. Write down the polypeptide chain sequence arising from the mRNA molecule of the question above, using the table of the genetic code (Table Q1 overleaf) and indicate the C- and the N-terminus of the peptide chain. Point mutations of a cytosine (C) often lead to the dysfunction of the APC protein. Write down all possible polypeptide chains that can result from all possible DNA mutations of cytosines, disregarding a mutation in the MET/START and STOP codons. I Specify which of the point mutations identified in (d) are redundant?
- Which of the following statements correctly describes the structure of chromatin around the promoter of an active eukaryotic gene? O A. It is in the form of heterochromatin and the nucleosomes are tightly wrapped. O B. It is in the form of euchromatin and the nucleosomes are cleared from the region allowing for an open and accessible configuration OC.A repressor protein is bound to the chromatin blocking RNA polymerase. O D.Both B and C.Imagine you are going to label a gene associated with apoptosis in Symbiodiniaceae with a Yellow Fluorescent Protein (YFP). To generate the YFP, you know the pre-MRNA looks as follows: Unspliced YFP premature mRNA Сap 5' UTR Exon 1 Intron Exon 2 Intron Exon 3 3' UTR Poly-A tail If Exon 2 is also required for mRNA stability, what can be predicted from the possible spliced alternative isoforms formed? One of the isoforms will not have a poly-A tail O The alternative splicing of YFP pre-MRNA prevents 5'-capping The MRNA isoform without Exon 2 will be degraded faster than the other isoform Exon 2 will be added to isoform B later to correct the mistake in splicing The protein translated from one of the mRNA isoforms will possess an additional functional domainWhich of these epigenetic changes could lead to reduced transcription of a particular gene? Please make sure to select all correct answer options. decreasing acetylation of histones associated with the nucleosomes of that gene inducing histone modifications that allow the formation of denser nucleosomes in the regulatory region of the gene Oincreasing acetylation of histones associated with the nucleosomes of that gene repositioning the nucleosomes associated to the gene to expose the enhancer and promoter DNA of the gene Uremoving histones to expose the enhancer and promoter DNA of the gene
- 1. Certain proteins that stimulate expression of a gene bind to DNA in a sequence specific manner and also induce conformational changes in the DNA. Describe the purpose of thses two modes of interaction with the DNA. 2. Draw the structures of the amino acid side chains that correspond to the following histone modification: a) acetylation of lysine; b) phosphorylation of serine; c) phosphorylation of histidine. How do thses modifications change the character of their respective side chain?You are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate this complex process, you decide to draw for the class a typical eukaryotic gene/transcription unit with its major regions, such as the promoter regions, where the RNA polymerase II and transcription factors would bind etc…. I need the correct answer please From the list given - choose all components that you think are part of a typical eukaryotic geneWhy must chromatin be remodeled at a eukaryotic promoter? Histone proteins must be added to the promoter so they can recruit RNA polymerase II Histone proteins are blocking promoter sequences recognized by general transcription factors (GTFs) Space needs to be made for the ribosome to bind to a nascent (i.e. newly transcribed) mRNA Because enhancer regions need to be exposed for general transcription factor binding To allow the spliceosome to remove exons from the mRNA during transcription
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