Understanding why these receptors are present when they are not supposed to be is important in finding new treatments for Cushing's syndrome. When the sequences for the promoters for the receptor genes were analyzed there was no common sequences found. This led to the theory that the loss of methylation of cytosine in the promoters of these genes was leading to their inappropriate expression. How could the loss of cytosine methylation lead to overexpression of the receptor genes? O a. Increased histone acetyltransferase activity O b. Decreased histone deacetylase activity Oc Decreased histone acetyltransferase activity O d. Increased histone deacetylase activity

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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Understanding why these receptors are present when they are not supposed to be is important in finding new
treatments for Cushing's syndrome. When the sequences for the promoters for the receptor genes were
analyzed there was no common sequences found. This led to the theory that the loss of methylation of
cytosine in the promoters of these genes was leading to their inappropriate expression.
How could the loss of cytosine methylation lead to overexpression of the receptor genes?
O a. Increased histone acetyltransferase activity
O b. Decreased histone deacetylase activity
Oc Decreased histone acetyltransferase activity
O d. Increased histone deacetylase activity
Transcribed Image Text:Understanding why these receptors are present when they are not supposed to be is important in finding new treatments for Cushing's syndrome. When the sequences for the promoters for the receptor genes were analyzed there was no common sequences found. This led to the theory that the loss of methylation of cytosine in the promoters of these genes was leading to their inappropriate expression. How could the loss of cytosine methylation lead to overexpression of the receptor genes? O a. Increased histone acetyltransferase activity O b. Decreased histone deacetylase activity Oc Decreased histone acetyltransferase activity O d. Increased histone deacetylase activity
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