Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Textbook Question
Chapter 9, Problem 15TYK
How would you set up an experiment to determine whether a hormone receptor is located on the cell surface or inside the cell?
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One such laboratory study investigated the binding of a hormone to three different receptor proteins in the cell membrane. The data collected are shown in the table below:
1) Provide a brief explanation as to why ligand binding to proteins must be a reversible process.
2) Calculate the dissociation constant (Kd) for the hormone binding to each of the three proteins.
3) Which of the proteins demonstrate the tightest/strongest binding of the hormone? Which demonstrates the least tight binding of the hormone? What is the basis for your answer?
What is the main benefit of cell signaling via direct physical contact and cell signaling over short distances (ex: nerve cell signaling)?
Which signaling molecule or molecules bind to a G-protein coupled receptor? (note: there may or may not be more then one answer)
a) cortisol
b) insulin
c) glucagon
d) calcium
e) cyclic AMP
f) epinephrine
Chapter 9 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 9.1 - What accounts for the specificity of a cellular...Ch. 9.2 - Prob. 1SBCh. 9.2 - Prob. 2SBCh. 9.3 - Prob. 1SBCh. 9.3 - Prob. 2SBCh. 9.3 - Prob. 3SBCh. 9.3 - Prob. 4SBCh. 9.3 - Prob. 5SBCh. 9.3 - Prob. 6SBCh. 9.4 - What distinguishes a steroid receptor from a...
Ch. 9.4 - By what means does a specific steroid hormone...Ch. 9.5 - Prob. 1SBCh. 9 - In signal transduction, which of the following is...Ch. 9 - Which of the following could not elicit a signal...Ch. 9 - A cell that responds to a signaling molecule is...Ch. 9 - Prob. 4TYKCh. 9 - Prob. 5TYKCh. 9 - Which of the following is incorrect about pathways...Ch. 9 - Which of the following would not inhibit signal...Ch. 9 - Prob. 8TYKCh. 9 - Prob. 9TYKCh. 9 - Prob. 10TYKCh. 9 - Discuss Concepts Describe the possible ways in...Ch. 9 - Discuss Concepts Is providing extra insulin an...Ch. 9 - Discuss Concepts There are molecules called GTP...Ch. 9 - Discuss Concepts Why do you suppose cells evolved...Ch. 9 - How would you set up an experiment to determine...Ch. 9 - Prob. 16TYKCh. 9 - Prob. 1ITDCh. 9 - Prob. 2ITDCh. 9 - Prob. 3ITD
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- How could we promote rapid or slow signaling for medical purposes? So there are many examples of slow and rapid signaling via coupled receptors. For an example, salivary gland secretion is rapid signaling and cell growth is slow signaling. These pathways could be twisted and used to resolve medical issues in a more natural and less damaging way. Are there any experiments that have or could be done to test out promoting rapid signaling to speed up slow processes such as cell growth in a severe wound? What experiments have or could be done to test out slowing down signaling that is fast like cells responding to their environment negatively (over-active allergies)? Thank you.arrow_forwardOne such laboratory study investigated the binding of a hormone to three different receptor proteins in the cell membrane. The data collected are shown in the table below Which of the proteins demonstrate the tightest/strongest binding of the hormone? Which demonstrates the least tight binding of the hormone? What is the basis for your answer?arrow_forwardHormones are chemical signaling molecules produced by specialized cells and transmitted via the circulatory system to all other cells in the body. Which of the following describes a condition that needs to be met for a target cell to re- ceive the signaling molecules? A B с D The size and shape of the target cell needs to be similar to that of the cell that secreted the hormone. The location of the target cell needs to be within the local region of the cell that secreted the hormone. The target cell needs to have sufficient ATP to transport the hormone into the cell. The cytosol of the target cell has to have receptors that recognize and bind the hormone.arrow_forward
- The binding of small amounts of hormones to target cell receptors triggers an intricate signal cascade. Why is the signal cascade necessary? Why not just have a simple molecularmechanism between the hormone and cellular effect?arrow_forwardWhat is the main benefit of cell signaling via direct physical contact and cell signaling over short distqnces (ex.: nerve cell signaling)?arrow_forwardWhat type of signal transduction is involved in signaling from hormones such as estrogen and testosterone? Explain the signal transduction pathway that occurs. 1. Is there a short term description for signal transduction, instead wrting multiple words to descripte the type of signal transduction? Can I just identify it as active signal transduction and inactive signal transduction. Based on my understanding, active singal transduction is for the fast react transdcution, while inactive signal transduction meanly refers the hormonal affacts on the system. 2. For Ion channels, specific enzymes are both involed activated and inactivated signal transduction?arrow_forward
- Although insulin initially acts through a tyrosine kinase receptor it also subsequently results in activation of a Ser/Thr protein kinase. Which one? A) Protein kinase A B) Protein kinase B C) Protein kinase C D) Ras E) Phosphoinositide-3-kinasearrow_forwardProgesterone is a steroid hormone that is produced by the placenta during pregnancy. Based on its structure (shown below), explain why progesterone’s effects are mediated by a receptor located inside the cell rather than on the cell membrane.arrow_forwardTesterone is a steriod (lipid) hormone. Which of the following would be the most likely receptor for this hormone? Select one: a. A transmembrane receptor in the cell membrane since it cannot diffuse across the cell membrane b. An intracellular receptor because it can diffuse across the cell membranearrow_forward
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license