(a)
Interpretation:
The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary
Concept introduction:
When
(b)
Interpretation:
The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.
Concept introduction:
When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favourable for enamine reactions.
(c)
Interpretation:
The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.
Concept introduction:
When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.
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Organic Chemistry (9th Edition)
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning