Concept explainers
(a)
Interpretation:
The major product of the given crossed Claisen condensation has to be stated.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
(b)
Interpretation:
The major product of the given crossed Claisen condensation is to be stated.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
(c)
Interpretation:
The major product of the given crossed Claisen condensation is to be stated.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
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Organic Chemistry (9th Edition)
- Predict the major product for the following reaction including stereochemistry. OHarrow_forwardPredict the major product of the following reactions. If it is possible, write all stereoisomers.arrow_forwardPredict the products of Claisen and crossed Claisen condensations, and proposemechanisms. Show how a Claisen condensation constructs the carbon skeleton of atarget moleculearrow_forward