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- Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.Although glucose cannot be formed from acetyl-CoA, triglycerides can enter the glycolytic pathway via which process? O Acetyl-CoA → oxaloacetate → phosphoenolpyruvate O Palmitoyl-CoAB- ketoacyl-CoA → a-ketoglutarate O Glycerol → DHAP Acyl-CoA glucoseMatch the regulatory molecule to the pathway that is regulated by that molecule in the liver. Answers may be used more than once, while some may not be used not at all. Glycolysis [Choose ] [Choose ] Malonyl-CoA Citric Acid Cycle NADH Citrate Fructose-2,6-Bisphosphate Epinephrine Fatty Acid Synthesis [Choose ] Fatty Acid Degradation/Beta Oxidation [ Choose ] Gluconeogenesis [ Choose ] >
- Which of the following statements is TRUE about fatty acid biosynthesis? Citrate carries malonyl CoA to the cytosol. O Acetyl ACP is the donor of the acetyl group. O NADPH is used as the reducing equivalent in the process. O The product detaches from the fatty acid synthase complex when the chain length is usually 18 carbons.Which of the following reactions required dihydrolipoyl dehydrogenase? Oxidative decarboxylation of pyruvate Oxidative decarboxylation of a-ketoglutarate Both A and B Neither A nor B Fatty acid biosynthesis is stimulated by: Decreased levels of citrate Increased levels of palmitoyl-CoA Increased levels epinephrine Increased levels of AMP All of the above None of the aboveFatty acids are activated for breakdown through the action of acyl-CoA synthestase. Which of the following statements regarding acyl-CoA synthetase is not true? ● It catalyzes the addition of CoA to the fatty acid One of the products of the reaction is ADP. O The free energy change for the reaction catalyzed by this reaction is close to 0 kJ/mol, but the subsequent hydrolysis of pyrophosphate drives the reaction forward. O The reaction results in the formation of a thioester bond.
- Which of these are components of animal fatty acid synthase (FAS)? ✔B-ketoacyl reductase enoyl reductase acetyl transacylase acyl CoA synthetase 3-hydroxyacyl dehydratase acyl CoA dehydrogenase Incorrect Fatty Acid Synthase (this diagram based on fungal FAS)A fatty acid (a long straight-chain carboxylic acid with an even number of carbons) is metabolized to acetylCoA, which can then enter the citric acid cycle to be further metabolized. A fatty acid with an odd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA. Propionyl-CoA cannot enter the citric acid cycle. Two coenzyme-requiring enzymes are needed to convert it to succinyl-CoA, a compound that can enter the citric acid cycle. Write the two enzyme-catalyzed reactions and include the names of the required coenzymes.choose the metabolic pathway being described in the statement choices: Digestion Glycolysis Formation of Acetyl CoA Krebs Cycle ETC Reactions Glycogenesis Glycogenolysis Gluconeogenesis 1. catalyzed initially by glycogen phosphorylase 2. breaking of glycosidic linkages of glycogen 3. requires pumping of hydrogen ions 4. lactic acid is converted to glucose
- In the pyruvae dehydrogensae complex, acetyl-coa is released by the dihydrolipoyl transacetylase activity. What is the purpose of the following enzymatic activity.If Vitamin B1 is deficient, which of the following intermediates is/are likely to accumulate inmitochondria? Pyruvate a-ketoglutarate Both A and B Neither A nor B Malonyl-CoA synthesized by the action of acetyl-CoA carboxylase II is primarily used: To synthesize fatty acids To inhibit fatty acid oxidation Both A and B Neither A nor BPyruvate dehydrogenase catalyzes the conversion of pyruvate to acetyl CoA. In this reaction, one molecule each of the catalytic coenzymes TPP, FAD and lipoamide participate in the reaction but are not consumed. OTrue O False