There is an animal that uses almost 100 percent of the oxygen in its blood. Analyzing the Hb of this animal, it’s found that 2,3-BPG does not bind to Hb, but bicarbonate ions do. Knowing that bicarbonate ions are strong negative allosteric effectors, what do you make of these findings? Why is the animal’s Hb not responsive to 2,3 BGP, but responsive to bicarbonate ions?

There is an animal that uses almost 100 percent of the oxygen in its blood. Analyzing the Hb of this animal, it’s found that 2,3-BPG does not bind to Hb, but bicarbonate ions do. Knowing that bicarbonate ions are strong negative allosteric effectors, what do you make of these findings? Why is the animal’s Hb not responsive to 2,3 BGP, but responsive to bicarbonate ions?

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter11: The Blood

Section: Chapter Questions

Problem 1SQE

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