Psilocybin is rapidly de-phosphorylated in the body into psilocin, which is anagonist For the 5-HT 2A Serotonin receptor, which binds the neurotransmitter serotonin as its natural ligand, and acts as a ligand-gated ion channel in the central nervous system. NH₂ HO. Serotonin (a) Part of the sequence of the 5-HT 24 Receptor is ...RQKACKVIGIVFFLFVVMWLAFFITNICDES... Identify the trans-membrane region within this sequence. Do you predict this sequence will Be transmembrane a-Helix or ß sheet? Why? (b) What is the distance spanned by this transmembrane region?

Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
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Chapter6: Cell Communication
Section6.3: Reception
Problem 2C
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Psilocybin is rapidly de-phosphorylated in the body into psilocin, which is anagonist
For the 5-HT 2A Serotonin receptor, which binds the neurotransmitter serotonin as its natural
ligand, and acts as a ligand-gated ion channel in the central nervous system.
HO.
Serotonin
(a) Part of the sequence of the 5-HT 24 Receptor is
NH₂
...RQKACKVIGIVFFLFVVMWLAFFITNICDES...
Identify the trans-membrane region within this sequence. Do you predict this sequence will
Be transmembrane a-Helix or ß sheet? Why?
(b) What is the distance spanned by this transmembrane region?
Transcribed Image Text:Psilocybin is rapidly de-phosphorylated in the body into psilocin, which is anagonist For the 5-HT 2A Serotonin receptor, which binds the neurotransmitter serotonin as its natural ligand, and acts as a ligand-gated ion channel in the central nervous system. HO. Serotonin (a) Part of the sequence of the 5-HT 24 Receptor is NH₂ ...RQKACKVIGIVFFLFVVMWLAFFITNICDES... Identify the trans-membrane region within this sequence. Do you predict this sequence will Be transmembrane a-Helix or ß sheet? Why? (b) What is the distance spanned by this transmembrane region?
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