Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 3, Problem 4P
Cohesion between sister chromatids, as well as tension created by the pull of kinetochore microtubules, is essentialto ensure efficient separation of chromatids at mitotic anaphase or in meiotic anaphase II. Explain why sister chromatid cohesion is important, and discuss the role of the proteins cohesin and separase in sister chromatid separation.
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Chapter 3 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 3 - Examine the following diagrams of cells from an...Ch. 3 - Our closest primate relative, the chimpanzee, has...Ch. 3 -
3. In a test of his chromosome theory of...Ch. 3 - Cohesion between sister chromatids, as well as...Ch. 3 - 5. The diploid number of the hypothetical animal...Ch. 3 - 6. An organism has alleles R1 and R2 on one pair...Ch. 3 - Explain how the behavior of homologous chromosomes...Ch. 3 - 8. Suppose crossover occurs between the homologous...Ch. 3 -
9. Alleles A and a are on one pair of autosomes,...Ch. 3 - Prob. 10P
Ch. 3 - Describe the role of the following structures or...Ch. 3 - A womans father has ornithine transcarbamylase...Ch. 3 - In humans, hemophilia A (OMIM 306700) is an...Ch. 3 -
14. A wild-type male and a wild-type female...Ch. 3 - 15. A woman with severe discoloration of her tooth...Ch. 3 - 16. In a large metropolitan hospital, cells from...Ch. 3 - In cats, tortoiseshell coat color appears in...Ch. 3 - 18. The gene causing Coffin–Lowry syndrome (OMIM...Ch. 3 - 19. Four eye-color mutants in Drosophila—apricot,...Ch. 3 - 20. For each pedigree shown,
a. Identify which...Ch. 3 - 21. Use the blank pedigrees provided to depict...Ch. 3 - 22. Figure 3.22 (page 89) illustrates reciprocal...Ch. 3 - 23. In fruit flies, yellow body (y) is recessive...Ch. 3 - 24. In a species of fish, a black spot on the...Ch. 3 - LeschNyhan syndrome (OMIM 300322) is a rare...Ch. 3 - 26. In humans, SRY is located near a...Ch. 3 - 27. In an 1889 book titled Natural Inheritance...Ch. 3 - 28. In Drosophila, the X-linked echinus eye...Ch. 3 - 29. A wild-type Drosophila male and female are...Ch. 3 - 30. Drosophila has a diploid chromosome number of...Ch. 3 - The cell cycle operates in the same way in all...Ch. 3 - 33. Form a small discussion group and decide on...Ch. 3 - 34. Duchenne muscular dystrophy (DMD; OMIM 310200)...Ch. 3 - Prob. 35P
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- Briefly explain why sister chromatids remain together in anaphase I but separate in anaphase II of meiosis.arrow_forwardConsider a diploid cell that contains 7 pairs of chromosomes. Each pair includes a maternal and a paternal member (for example: AP pair) or AP B ^ n * B ^ p (two pairs). How many different combinations of chromatids are possible during the early phases of anaphase in meiosis II?arrow_forwardMeiosis is characterized by the pairing of homologouschromosomes during prophase I. In many species, an elaboratestructure called the synaptonemal complex forms betweenhomologues. During this pairing, homologues may exchangechromosomal material at sites called chiasmata. In meiosis I, thehomologues separate from each other, reducing the chromosomenumber to the haploid state (thus the reductive division). It isfollowed by a second division without replication, during whichsister chromatids become separated. The result of meiosis I and IIis four haploid cells. If sister chromatids separated at the first division, would meiosis still work?arrow_forward
- consider a diploid cell that contains three pairs of chromosomes designated AA, BB, and CC. Each pair contains a maternal and a paternal member (e.g., Am and Ap, etc.). Using these designations, demonstrate your understanding of mitosis and meiosis by drawing chromatid combinations as requested. Be sure to indicate when chromatids are paired as a result of replication and/or synapsis. You may wish to use a large piece of brown manila wrapping paper or a large cut-up paper bag and work with another student as you deal with these problems. Such cooperative learning may be a useful approach as you solve problems throughout the text. Draw all possible combinations of chromatids during anaphase II in meiosis.arrow_forwardSomatic cells in organisms of a particular diploidplant species normally have 14 chromosomes. Thechromosomes in the gametes are numbered from 1through 7. Rarely, zygotes are formed that containmore or fewer than 14 chromosomes. For each of thezygotes below, (i) state whether the chromosomecomplement is euploid or aneuploid; (ii) provideterms that describe the individual’s genetic makeupas accurately as possible; and (iii) state whether ornot the individual will likely develop through theembryonic stages to make an adult plant, and if so,whether or not this plant will be fertile.a. 11 22 33 44 5 66 77b. 111 22 33 44 555 66 77c. 111 222 333 444 555 666 777d. 1111 2222 3333 4444 5555 6666 7777arrow_forwardA sexually reproducing organism has the following phenotype DdEeAaTt: The D and E loci are on the same arm of a metacentric chromosome in cis configuration. The A locus is on the long arm of an acrocentric chromosome and the T locus is on a telocentric chromosome. There are no other chromosomes. Using diagrams, show a cell at metaphase of mitosis and show the results of mitosis. Ensure you show the location of the gene loci on the different chromosomes.arrow_forward
- Random orientation of homologous chromosomal pairs along the metaphase plate of the cell occurs during which phase of meiosis?arrow_forwardFor below problem, consider a diploid cell that contains three pairs of chromosomes designated AA, BB, and CC. Each pair contains a maternal and a paternal member (e.g., Am and Ap). Using these designations, demonstrate your understanding of mitosis and meiosis by drawing chromatid combinations as requested. Be sure to indicate when chromatids are paired as a result of replication and/or synapsis. You may wish to use a large piece of brown manila wrapping paper or a cut-up paper grocery bag for this project and to work in partnership with another student. We recommend cooperative learning as an efficacious way to develop the skills you will need for solving the problems presented throughout this text. Question: Assume that each gamete resulting from Problem 29 fuses, in fertilization, with a normal haploid gamete. What combinations will result? What percentage of zygotes will be diploid, containing one paternal and one maternal member of each chromosome pair?arrow_forwardAt what stage of mitosis can the kind and number of chromosomes be easily detected and determined? How does non disjunction in meiosis lead to numerical chromosomal aberration? If cell division during gametogenesis is non meoitic, what is its consequence to the future generations of diploid organisms? What is the relationship between meiosis and fertilization?arrow_forward
- A simple diagram indicating the alterations in genetic content throughout mitosis could be prepared as follows: 2n 2n 2n duplicated 4n 2n above). Include all of the cells generated at each stage. (G1) (S phase) (G2, Prophase, Metaphase) (Anaphase) (Telophase) (Cytokinesis) prepare a similar diagram for meiosis, starting with a diploid cell in G1 (asarrow_forwardSuppose the diagram below shows a cell during metaphase Meiosis II: microtubule a) Label the elements of the figure. b) Assuming all of the chromosomes present during Meiosis II are shown in the figure above, how many chromosomes (counting homologous pairs as two chromosomes a cell from this organism have immediately after fertilization? Tne left Showarrow_forwardA diploid species has four chromosomes per set for a total of eightchromosomes in its somatic cells. Draw such a cell as it wouldlook in late prophase of meiosis II and prophase of mitosis. Discuss how prophase of meiosis II and prophase of mitosis differfrom each other, and explain how the difference originates.arrow_forward
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