Concept explainers
For each pedigree shown,
a. Identify which simple pattern of hereditary trans-mission (autosomal dominant, autosomal recessive, X-linked dominant, or X-linked recessive) is most likely to have occurred. Give genotypes for individuals involved in transmitting the trait.
b. Determine which other pattern(s) of transmission is/are possible. For each possible mode of transmission, specify the genotypes necessary for transmission to occur.
c. Identify which pattern(s) of transmission is/are impossible. Specify why transmission is impossible.
Learn your wayIncludes step-by-step video
Chapter 3 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Additional Science Textbook Solutions
Campbell Biology in Focus
Human Anatomy & Physiology
Concepts of Genetics (12th Edition)
Campbell Biology: Concepts & Connections (9th Edition)
Laboratory Experiments in Microbiology (12th Edition) (What's New in Microbiology)
Brock Biology of Microorganisms (15th Edition)
- A. For the following genotypes state the ABO blood phenotype. JAJA |B|O_ 101⁰_ |A|B_ B. Using genetic diagrams, show how it is possible for a couple with a type A mother and a type B father can have a child with type O blood. C. Using genetic diagrams show how a type AB person with a type O partner have offspring that share neither of their phenotypes.arrow_forwardA. How does the structure of a Barr body affect gene expression? B. Color-blindness is an X-linked recessive trait. Heterozygous females are not color blind but they can sometimes have partial color blindness. Explain how this can occur.arrow_forwardE. D. A. B. 11. C. Huntington's disease is a degenerative disease of the nervous system that strikes in middle age. The allele that causes the disease (H) is dominant to the allele that results in the normal condition (h). Answer the following questions about the inheritance of this disease. What is the genotype of a man who is normal but whose father had Huntington's disease? What is the genotype of a woman who has Huntington's disease if both of her parents had Huntington's disease? If a man who is heterozygous for Huntington's disease marries a woman who is normal, what would you expect for the genotypes and phenotypes of their children? If a normal man marries a woman who is homozygous for Huntington's disease, what do you expect for the genotypes and phenotypes of their children? Since Huntington's disease is caused by a dominant allele, does this mean it's also the most common allele in the population? F. Since Huntington's disease is caused by a dominant allele, does this mean…arrow_forward
- Faulty Tooth Enamel Formation Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is notexpressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental…arrow_forwardAmelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is notexpressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental cross, and identify the possible…arrow_forwardAmelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is not expressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental cross, and identify the…arrow_forward
- Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is not expressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental cross, and identify the…arrow_forwardA. Identify the most likely inheritance pattern in the pedigree below. B. What are the genotypes of individuals II-3 and Il-4? Use any letter for your example. 1 2 II 1 2 3 4 5 II 1 2 3 4 5 6arrow_forwardA. Identify the type of inheritance from the given options below. Write only the letters of your answer, i.e. AD for autosomal dominant.Autosomal Dominant Autosomal Recessive X-Linked Recessive Y-Linked B. Give the possible genotype of the AFFECTED individuals. In indicating the genotype of affected individual, specify the generation and number where the individual belongs, i.e. II-3 AA; III-1 aa See attached image.arrow_forward
- 1) Symptoms of 4 disorders are listed. Using the lists given, fill in the correct letter for the condition name and inheritance type. Letters may be used more than once. Symptoms Condition Inheritance Туре Loss of muscle control and decline in mental ability Shades of red and green are hard to distinguish Lack of skin pigmentation Cannot produce one of the necessary blood clotting factors Conditions: Inheritance Type: A: Albinism E: X-linked dominant B: Huntington Disease F: X-linked recessive G: Y-linked C: Hemophilia H: Autosomal dominant I: Autosomal recessive D: CVDarrow_forwarda. What are the other systems of blood typing? What are the modes of inheritance of these groups? Fill up the table. BLOOD GROUPS MODE OF INHERITANCE b. What are the applications of the genetics of blood typing? List at least three.arrow_forwardMarfan syndrome is an autosomal dominant disorder caused by mutations in the FBN1 gene. It affects connective tissues, commonly resulting in long bones, abnormal curvature of the spine, defects in the eye (glaucoma), and faulty heart valves.X-linked hypophosphatemia is an X-linked dominant disorder that causes a type of rickets. Which of the following rows describes the inheritance pattern of these disorders? Select one: a. Marfan Syndrome X-linked Hypophosphatemia Males are affected more frequently than females. Female carriers can pass on the trait to their sons. b. Marfan Syndrome X-linked Hypophosphatemia Males and females are affected with equal frequency. Affected males can only pass on the trait to their daughters. c. Marfan Syndrome X-linked Hypophosphatemia Affected males can only pass on the trait to their daughters. Males and females are affected with equal frequently. d. Marfan Syndrome X-linked Hypophosphatemia Female carriers can…arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education