Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 3, Problem 19P

Four eye-color mutants in Drosophila—apricot, brown, carnation, and purple—are inherited as recessive traits. Red is the dominant wild-type color of fruit-fly eyes. Eight crosses (A through H) are made between parents from pure-breeding lines.

Chapter 3, Problem 19P, 19. Four eye-color mutants in Drosophila—apricot, brown, carnation, and purple—are inherited as

a. Which of these eye-color mutants are X-linked recessive and which are autosomal recessive? Explain how you distinguish X-linked from autosomal heredity.

b. Predict F2 phenotype ratios of Crosses A, B, D, and G.

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In Drosophila, an X-linked recessive mutation, Xm causes miniature wings. List the F2 phenotypic ratios if: a miniature-winged female is crossed with a normal male and a miniature-winged male is crossed with a normal female. What would the phenotypic ratio from (a) be if the miniature-winged gene were autosomal? Assume in all cases that the P1 individuals are true-breeding.
Vestigial wing is a recessive autosomal mutation in the fruit fly Drosophila melanogaster. Wild-type flies have red eyes, but another mutation, an X-linked recessive mutation causes white eyes. You cross a parental generation of males with vestigial wings with females that have white eyes. 1) What phenotypic ratio would you expect in the F1 generation from such a cross? What phenotypes do you observe in these flies? (e.g. males with red eyes and wild-type wings). 2) What phenotypic ratio would you expect in the F2 generation? What phenotypes do you observe in these flies?
You have a Drosophila line that is homozygous for autosomal recessive alleles a, b, and c, linked in that order. You cross females of this line with males homozygous for the corresponding wild-type alleles. You then cross the F1 heterozygous males with their heterozygous sisters. You obtain the following F2 phenotypes (where letters denote recessive phenotypes and pluses denote wild-type phenotypes): 1364 + + +, 365 a b c, 87 a b +, 84 + + c, 47 a + +, 44 + b c, 5 a + c, and 4 + b +.a. What is the recombinant frequency between a and b? Between b and c? (Remember, there is no crossing over in Drosophila males.)b. What is the coefficient of coincidence?

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Genetic Analysis: An Integrated Approach (3rd Edition)

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY