You are trying to determine, which if any of the children of Brenda and Ike are actually fathered by Ike. You analyze 2 genes known to contain variable numbers of repeats by PCR and Gel Electrophoresis and get the following results Ike Brenda Joe Tina Holly Holly Ralph Ike Brenda Joe Tina Holly Ralph Based on this information a) Tina must be the child of Ike and Brenda b) Tina could be the child of Ike and Brenda c) Tina can not be the child of Ike and Brenda Gene 1 Gene 2
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Genetics Question 9
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- Pedigree Analysis Is a Basic Method in Human Genetics Using the pedigree provided, answer the following questions. a. Is the proband male or female? b. Is the grandfather of the proband affected? c. How many siblings does the proband have, and where is he or she in the birth order?Three newborn bables have been separated from their parents. You need to make sure that each child is reunited with the proper set of parents. The data below was gathered by amplifying two VNTR loci in each baby and the possible parents. Fragments were then separated using gel electrophoresis. Assume that each parent couple had only one of the babies. Match the babies with the proper parents. VNTR Locus 1 Baby 1 Baby 2 Baby 3 Jeff Jane David Dianna Mike Maddle VNTR Locus 2 Baby 1 Baby 2 Baby 3 Jeff Jane David Dianna Mike Maddie Baby y Choose... Mike and Maddie Baby David and Dianna Jeff and Jane BabyThe diagram below represents results of agarose gel electrophoresis performed after PCR amplification of a molecular marker in diploid organisms. Answer the following questions: a) How many individuals are homozygous and how many are heterozygous? b) How many alleles are there in this population?
- The picture shows a gel of PCR products for the loci SRY, AMELX/Y and ZFX/Y, for three controls and five test human individuals (1-5). Below the gel is the phenotypic sex of each individual, their fertility status, and the number of Barr bodies seen in the nucleus of a somatic cell in each case. The diagram to the right shows the positions of the tested loci on the human sex chromosomes, and also the positions of the PRKX and PRKYgenes. Which sample carries a derived X chromosome with a translocation due to ectopic crossover between the loci PRKX and PRKY: 46,X,derX,t(X,Y); ? 1 2 3 4 5Consider the first category of test-cross offspring shown in figure 8.2 (+b, LS). Consider also that the parents of the heterozygous female flies in the test cross had the following genotypes: bb, SS, and +, LL. A. What would be the physical phenotype of these flies? B. If PCR was conducted with the DNA of one of these flies using the primers for the molecular marker, what would be the appearance of the bands on an electrophoresis gel with the PCR products? C. If the gene for black body and the locus for the molecular marker (L long or S short) were unlinked, what proportion of the test-cross progeny would be black flies that are heterozygous for the molecular marker? What proportion would be flies with normal body color, which are homozygous for one form of the molecular marker? D. If the gene for black body and the locus for the molecular marker were linked, how would the proportion of flies be different?A female cheetah recently gave birth while in captivity; however, the paternity of the infant is unclear. Scientists tested the DNA from two male cheetahs, along with the female and offspring. The resulting electrophoresis gel is shown. Based on the gel electrophoresis results, what can be concluded about the paternity of the offspring?
- Based on the table below, what is the order of the genes examined? a b с d A B C/C B A Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. A C B/B C A CAB/BAC Phenotype of testcross ССА/АСС A,C C A, B, C A B, C A, B B Genotype of hybrid gamete Abc ab C A B C Abc a B C abc е Not enough information A B C a B c # of progeny 388 5 50 64 51 47 5 390 1000Using the data below please identify the following: Identify which of the siblings in generation II has a recombinant chromosome. Determine which of his/her children is at risk of developing adenomatous polyposis based on the new data. Table 2 RFLP data for a family suffering from APC syndrome. III1 III2 III3 II1 II2 III4 III5 III6 I1 I2 II3 II4 III7 II5 II6 III8 III9 III10 II7 II8 III11 III12 III13 II9 II10 A A A A A A A A A A A A B B B B B B B B B B B B B B B B B B B C C C C C C C C D D D D D D DObserve the following DNA profile produced by STR analysis Which child or children could be both this mother's and this father's children? Question Options: 1) Child #2 and #3 2) Child #2 3) Child #1 and Child #3 4) Child #1 asap typed only
- An important application of DNA fingerprinting is relationship testing. Persons who are related genetically have some bands or peaks in common. The number they share depends on the closeness of their genetic relationship. For example, an offspring is expected to receive half of his or her minisatellites from one parent and the rest from the other. The diagram shown here schematically illustrates traditional DNA fingerprints of an offspring, mother, and two potential fathers. In paternity testing, the offspring’s DNA fingerprint is first compared with that of the mother. The bands that the offspring have in common with the mother are depicted in purple. The bands that are not similar between the offspring and the mother must have been inherited from the father. These bands are depicted in red. Which male could be the father?DNA fingerprinting involves using restriction enzymes to cut DNA at a specific sequence, resulting in many fragments of different lengths. Gel electrophoresis then separates the fragments according to size. DNA fingerprints produced from four different individuals is shown below. The DNA for Individuals 3 and 4 could NOT be Select one: a. mitochondrial DNA from two people who have the same maternal grandmother (both their mothers had the same mother) b. mitochondrial DNA from two people who have the same paternal grandmother (both their fathers had the same mother) c. nuclear DNA from identical twins d. nuclear DNA isolated from a hair left at a crime scene and a buccal swab from a suspect who was present at the crimeWho invented/proposed the use of Punnett square in studying genetics? Give a short description of him/her.