What is the minimal resolution required for gleaning insights into structures of drug-drug target complex? 100A 2.5A 5A
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What is the minimal resolution required for gleaning insights into structures of drug-drug target complex?
- 100A
- 2.5A
- 5A
- 10A
- 0.5A
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- What are the different methods for developing modified release drug delivery system ? Discuss about the matrix and encapsulation drug release systems. Please explain at your own words.Please Write the Drug Discovery Process of Diltiazem? Please write at your own words.What are the potential implications of genetic variations in drug-metabolizing enzymes on individual response and therapeutic outcomes in clinical pharmacology?
- What is DPI? What are the advantages of DPI over MDI? How drug is aerosolized from a DPI system? Please answer at your own words.Give typed full explanation What is the possible positive frame of references for a study of a new drug with minimum improvement after initial testing?what is pharmacophore? what is the importance of pharmacophore in drug discovery?
- (c) Molnupiravir has not been approved but has been authorized for emergency use by the FDA under an EUA to treat mild to moderate COVID-19 infection. Briefly explain this decision made by FDA based on the knowledge of clinical trials. (d) Both drugs are not allowed to be prescribed to person under 18 years old due to insufficient clinical data. Why is it necessary to separately conduct clinical trials for a younger age group?What is high throughput screening in the discovery of drug ?What properties of drug are relevant for developing modified release drug delivery formulation. Please briefly explain this at your own words.
- How does physicochemical properties of a drug define its biological mechanism? Please explain at your own words.How we can establish or improve Structure activity relationship(SAR) for the development of H1-Antihistamine drug?What are Targeted drug delivery systems ? Please explain the ideal properties of Targeted drug delivery systems?