Examine the following theoretical operon (gen) in E. coli which contains structural genes (genC, genB, genA) that are involved in amino acid biosynthesis. The gen operon also includes the gene encoding for the regulator molecule within it. When the amino acid that this operon helps synthesize is present, it binds to the regulator forming a complex which can bind to the operator region. Assume that the regulator molecule only binds to the operator in the presence of the amino acid. Promoter || Operator genC genB gen operon Regulator genA Question 3 Assume each gene in the gen operon has its own start and stop codons. How would a nonsense mutation in the genB region influence the expression of the gen operon in the absence of the amino acid? A. Gain of function B. Loss of function C. Null D. Silent E. Insufficient information Question 3 Assume each gene in the gen operon has its own start and stop codons. How could a base substitution mutation in the operator region influence the expression of the gen operon in the abundance of the amino acid? A. Gain of function B. Loss of function C. Null D. Silent E. Insufficient information

Human Anatomy & Physiology (11th Edition)
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Examine the following theoretical operon (gen) in E. coli which contains structural genes (genC, genB,
genA) that are involved in amino acid biosynthesis. The gen operon also includes the gene encoding for
the regulator molecule within it. When the amino acid that this operon helps synthesize is present, it
binds to the regulator forming a complex which can bind to the operator region. Assume that the
regulator molecule only binds to the operator in the presence of the amino acid.
Promoter
||
Operator
genC
genB
gen operon
Regulator
genA
Transcribed Image Text:Examine the following theoretical operon (gen) in E. coli which contains structural genes (genC, genB, genA) that are involved in amino acid biosynthesis. The gen operon also includes the gene encoding for the regulator molecule within it. When the amino acid that this operon helps synthesize is present, it binds to the regulator forming a complex which can bind to the operator region. Assume that the regulator molecule only binds to the operator in the presence of the amino acid. Promoter || Operator genC genB gen operon Regulator genA
Question 3
Assume each gene in the gen operon has its own start and stop codons.
How would a nonsense mutation in the genB region influence the expression of the gen operon
in the absence of the amino acid?
A. Gain of function
B. Loss of function
C. Null
D. Silent
E. Insufficient information
Question 3
Assume each gene in the gen operon has its own start and stop codons.
How could a base substitution mutation in the operator region influence the expression of the
gen operon in the abundance of the amino acid?
A. Gain of function
B. Loss of function
C. Null
D. Silent
E. Insufficient information
Transcribed Image Text:Question 3 Assume each gene in the gen operon has its own start and stop codons. How would a nonsense mutation in the genB region influence the expression of the gen operon in the absence of the amino acid? A. Gain of function B. Loss of function C. Null D. Silent E. Insufficient information Question 3 Assume each gene in the gen operon has its own start and stop codons. How could a base substitution mutation in the operator region influence the expression of the gen operon in the abundance of the amino acid? A. Gain of function B. Loss of function C. Null D. Silent E. Insufficient information
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