Membrane iver Cell Glucose 6-Phosphate Glycolysis = Activates = Inhibits Glucose 1-Phosphate PKB GSK3 1 Glycogen Synthase PK Insulin Receptor Glycogen Phosphorylase Glucagon Glycogen Glucagon Receptor

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter19: The Peripheral Endocrine Glands
Section: Chapter Questions
Problem 13UC
icon
Related questions
icon
Concept explainers
Question
100%

Diabetes often results in the production of reduced levels of insulin. Researchers claim that a drug that binds to and blocks the active site of GSK3 might mimic the role of insulin in the pathway shown in Figure 2. Provide reasoning to justify the researchers' claim.

Cell Membrane
of a Liver Cell
Glucose
6-Phosphate
Glycolysis
→→ = Activates
= Inhibits
Glucose
1-Phosphate
Insulin
PKB
GSK3
1
Glycogen
Synthase
PK
Glycogen
Phosphorylase
-<|
Insulin Receptor
Glucagon
Glycogen
Glucagon
Receptor
Transcribed Image Text:Cell Membrane of a Liver Cell Glucose 6-Phosphate Glycolysis →→ = Activates = Inhibits Glucose 1-Phosphate Insulin PKB GSK3 1 Glycogen Synthase PK Glycogen Phosphorylase -<| Insulin Receptor Glucagon Glycogen Glucagon Receptor
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Metabolic pathways
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Physiology: From Cells to Systems (MindTap …
Human Physiology: From Cells to Systems (MindTap …
Biology
ISBN:
9781285866932
Author:
Lauralee Sherwood
Publisher:
Cengage Learning
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Principles Of Pharmacology Med Assist
Principles Of Pharmacology Med Assist
Biology
ISBN:
9781337512442
Author:
RICE
Publisher:
Cengage
Biology: The Unity and Diversity of Life (MindTap…
Biology: The Unity and Diversity of Life (MindTap…
Biology
ISBN:
9781337408332
Author:
Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:
Cengage Learning