Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Chapter 35, Problem 2VCQ
Figure 35.11 Potassium channel blockers, such as amiodarone and procainamide, which are used to treat abnormal electrical activity in the heart, called cardiac dysrhythmia, impede the movement of K+ through voltage-gated K+ channels. Which part of the action potential would you expect potassium channels to affect?
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In an experiment, the extracellular [Na+] surrounding a nerve cell was reduced from 145 to 45 mM. Which of the following is the most likely effect of this on action potentials?
No action potentials would occur because the concentration of extracellular Na+ is too low.
The membrane potential would become more negative so the threshold for action potential generation could not be reached.
The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarisation phase would be slower.
The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarization phase would be more rapid.
The compound tetraethylammonium (TEA) blocks the voltage-gated changes in potassium permeability that occurs during an action potential. After administration of TEA, what changes would you expect in the action potential?
The voltage produced by a single nerve or muscle cell is quite small, but there are many species of fish that use multiple action potentials in series to produce significant voltages. The electric organs in these fish are composed of specialized disk-shaped cells called electrocytes. The cell at rest has the usual potential difference between the inside and the outside, but the net potential difference across the cell is zero. An electrocyte is connected to nerve fibers that initially trigger a depolarization in one side of the cell but not the other. For the very short time of this depolarization, there is a net potential difference across the cell, as shown. Stacks of these cells connected in series can produce a large total voltage. Each stack can produce a small current; for more total current, more stacks are needed, connected in parallel.
In an electric eel, each electrocyte can develop a voltage of 150 mV for a short time. For a total voltage of 450 V, how many electrocytes must…
Chapter 35 Solutions
Biology 2e
Ch. 35 - Figure 35.3 Which of the following statements is...Ch. 35 - Figure 35.11 Potassium channel blockers, such as...Ch. 35 - Figure 35.26 Which of the following statements is...Ch. 35 - Neurons contain _____ which can receive_____...Ch. 35 - A(n)______neuron has one axon and one____ dendrite...Ch. 35 - Glia that provide myelin for neurons in the brain...Ch. 35 - Meningitis is a viral or bacterial infection of...Ch. 35 - For a neuron to fire an action potential, its...Ch. 35 - After an action potential, the opening of...Ch. 35 - What is the term for protein channels that connect...
Ch. 35 - Which of the following molecules is not involved...Ch. 35 - Thelobe contains the visual cortex frontal...Ch. 35 - Theconnects the two cerebral hemispheres. limbic...Ch. 35 - Neurons in Thecontrol motor reflexes. thalamus...Ch. 35 - Phineas Gage was a 19th century railroad worker...Ch. 35 - Activation of the sympathetic nervous system...Ch. 35 - Where are parasympathetic preganglionic cell...Ch. 35 - ______ is released by motor nerve endings onto...Ch. 35 - Parkinson’s disease is a caused by the...Ch. 35 - __________ medications are often used to treat...Ch. 35 - Strokes are often caused by. neurodegeneration...Ch. 35 - Why is it difficult to identify the cause of many...Ch. 35 - Why do many patients with neurodevelopmentaJ...Ch. 35 - How are neurons similar to other cells? How are...Ch. 35 - Multiple sclerosis causes demyelination of axons...Ch. 35 - Many neurons have only a single axon, but many...Ch. 35 - How does myelin aid propagation of an action...Ch. 35 - What are the main steps in chemical...Ch. 35 - Describe how long-term potentiation can lead to a...Ch. 35 - What methods can be used to determine the function...Ch. 35 - What are the main functions of the spinal cord?Ch. 35 - Alzheimer’s disease involves three of the four...Ch. 35 - What are the main differences between the...Ch. 35 - What are the main functions of the sensory somatic...Ch. 35 - Describe how the sensory-somatic nervous system...Ch. 35 - Scientists have suggested that the autonomic...Ch. 35 - What are the main symptoms of Alzheimer’s disease?Ch. 35 - What are possible treatments for patients with...
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- Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forwardAssume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and presynaptic excitatory neuron B terminates on the same postsynaptic cell on a dendrite located on the side of the cell body opposite the axon hillock. Explain why rapid firing of presynaptic neuron A could bring the postsynaptic neuron to threshold through temporal summation, thus initiating an action potential, whereas firing of presynaptic neuron B at the same frequency and the same magnitude of EPSPs may not bring the postsynaptic neuron to threshold.arrow_forwardExperimenters injected bark scorpion venom into mouse neurons and measured how many action potentials were generated after the venom was introduced. Is it possible that the venom could be affecting the activity of a voltage-gated potassium channel? What effect could the venom have on a voltage-gated potassium channel to produce this result?arrow_forward
- Based upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Helparrow_forwardAn action potential is considered an "all or nothing" event. What does this mean? Explain using the picture below to discuss what happens during each event. Use the letters in the diagram to match the events. +40- В -C 0- -40- E -60- -80- A 1 3 4 Time (msec) MAR 15 w MacBook Air 888 F2 F3 F4 F5 F7 FB F10 %23 24 & 3 4 6 8 %3D E T Y P 11 C V M command option Membrane potential (mV) .. ..arrow_forwardConsider the following three diagrams of a nerve cell membrane. They show resting potential, depolarization, and hyperpolarization. Figure out which one is which, then draw them in the order they occur in a cell that undergoes an action potential outside + Na* inside K* Na* Nat K Nat K Na potential: -80 mV outside + Na K* Na* inside Na+ K Nat Na* K+ potential: +30 mV outside Na Na Na Na* K+ inside K* Na* Kt potential: -70 mVarrow_forward
- Consider the following graph of an action potential: 60- 30 membrane potential (mV) 9 -30 -60 line X -90- What is happening at point "C"? Sodium channels are opening Sodium channels are closing Potassium channels are opening Potassium channels are closing Sodium channels are closing and potassium channels are opening Sodium channels are opening and potassium channels are closing time line Oarrow_forwardDendrotoxins, produced by the mamba snakes (Dendroaspis), are inhibitors of the voltage-gated K+ channels. What phase of the action potential would this toxin affect? How would it affect ion permeability during this phase? How would ion movement be affected?arrow_forwardDraw details of the repolarization phase of an action potential from the following descriptions of the sequences of AfterHyperPolarization (AHP) and AfterDePolarization (ADP) sequences. Make the distinct phases clear and noticeable (5 % each) A complex AHP consisting of a first component AHP, an ADP, and a second component AHP before repolarization to resting membrane potential a first fast AHP component, followed by a slower AHP, followed by a fast ADP, and a second late AHP component before repolarization to restarrow_forward
- Which of the following events correctly ranks steps in an action potential? 1. Voltage-gated sodium and potassium channels transition from closed to open states allowing sodium ions to enter and potassium ions to exit. 2. Voltage-gated sodium channels transition from open to inactivated states. 3. Ligand-gated sodium channels are triggered to open. 4. Peak potassium permeability. 5. Peak sodium permeability. 6. Membranes hyperpolarize due to more potassium ions exiting cell and neuron enters refractory period. 7. Critical threshold is achieved. O 3, 1, 7, 5, 2, 4, 6 O 3, 7, 1, 5, 4, 6, 2 O 3, 4, 1, 2, 6, 7,5 O 6, 7, 3, 2, 5, 4, 1 O 7, 5, 3, 1, 4, 6, 2 4, 6, 3, 7, 5, 2, 1arrow_forwardAfter an action potential has been initiated, there are two processes that prevent the membrane from remaining depolarized forever. What are these two processes? activation of ligand-gated channels activation of the Na/K pump activation of voltage-gated K+ channels activation of voltage-gated Na+ channels inactivation of ligand-gated channels inactivation of the Na/K pump inactivation of voltage-gated K+ channels inactivation of voltage-gated Na+ channelsarrow_forward1) A 100-um diameter nerve axon has the following properties: rm = 2.5 x 104 ohm x cm, ri = 1 x 105 ohm/cm, r0 = 0, cm = 3 x 10-8 F/cm. The permeability to Cl- is very high and Cl- ions are at resting potential Vm. A steady inward current is injected into the axon resulting in a Vm of -110 mV at the site of current injection. If the Vm 3 mm from the site of injection is -94.5 mV, what is the resting Vm?arrow_forward
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