Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 23, Problem 20P
Understanding a Ubiquitous Series of Metabolic Reactions Study Figure 23.9. Where else in
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Create a Venn-Diagram to compare & contrast CATABOLISM vs ANABOLISM such as its process/mechanism, relation with ATP, reaction type, etc. Moreover, provide at least two (2) specific metabolic pathways as examples for each.
You can use coloring pens, crayons, and the like to make your presentation look appealing. Digital drawings are also acceptable.
DRAW IT Using a series of arrows, draw the branched metabolicreaction pathway described by the following statements, andthen answer the question at the end. Use red arrows and minussigns to indicate inhibition.L can form either M or N.M can form O.O can form either P or R.P can form Q.R can form S.O inhibits the reaction of L to form M.Q inhibits the reaction of O to form P.S inhibits the reaction of O to form R.Which reaction would prevail if both Q and S were present inthe cell in high concentrations?(A) L S M(B) M S O(C) L S N(D) O S P
Integration of Metabolism
Complete the interrelated pathways by providing the necessary metabolite, enzyme, and reaction or metabolic pathway. Abbreviations and acronyms for pathways, metabolites, products and enzymes will not be accepted (For coenzymes, you may use abbreviations/acronyms).
Fill the blank in numbers 1-20
Chapter 23 Solutions
Biochemistry
Ch. 23 - Prob. 1PCh. 23 - Determining the Amount of ATP Produced from Fatty...Ch. 23 - Prob. 3PCh. 23 - Examining the Labeling of Glucose from 14C.labeled...Ch. 23 - Prob. 5PCh. 23 - Prob. 6PCh. 23 - Prob. 7PCh. 23 - Prob. 8PCh. 23 - Prob. 9PCh. 23 - Prob. 10P
Ch. 23 - Prob. 11PCh. 23 - Understanding Human Energy Consumption During...Ch. 23 - Prob. 13PCh. 23 - Prob. 14PCh. 23 - Prob. 15PCh. 23 - Extending the Mechanism of Methylmalonyl-CoA...Ch. 23 - Prob. 17PCh. 23 - Prob. 18PCh. 23 - Prob. 19PCh. 23 - Understanding a Ubiquitous Series of Metabolic...Ch. 23 - Using the ActiveModel for enoyl-CoA dehydratase,...
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- How Is Metabolism Regulated? (Integrates with Chapter 15.) Metabolic regulation is achieved via regulating enzyme activity in three prominent ways: allosteric regulation, covalent modification, and enzyme synthesis and degradation. Which of the.se three modes of regulation is likely to be the quickest; which the .slowest? For each of these general enzyme regulatory mechanisms, cite conditions in which cells might employ that mode in preference to either of the other two.arrow_forwardHow Do Vitamin-Derived Coenzymes Aid Metabolism? What chemical functionality is provided to enzyme reactions by pyridoxal phosphate (we Chapter 13)? By coenzyme A (see Chapter I9)? By vitamin B12 (see Chapter 23)? By thiamine pyrophosphate (see Chapter 19)?arrow_forwardDraw the Gluconeogenesis pathway (pyruvate to glucose) and identify the different types of organic reaction mechanisms. Make sure to draw the structures of each biomolecule included in the pathway. Identify at most 5 organic reactions in the metabolic pathway.arrow_forward
- Biological oxidation refers to the process in which organisms oxidize and decompose organic matter to produce carbon dioxide and water and release energy. Common forms in human body are (1) direct transfer of hydrogen atoms, or (2) adding water first and then dehydrogenation (i.e. indirect oxygen addition). Please give one example of each metabolic pathway, and ask for the names of specific substrates, products and enzymes.arrow_forwardCould you help me with a scheme following: Carboxylic acids do not readily undergo certain biochemical reactions; thus, they are often converted to thioesters or phosphonoesters for catalysis. What are two reactions that thioesters and phosphonoesters can undergo that carboxylic acids cannot? Show enzyme-catalyzed arrow pushing for both of these mechanisms.arrow_forwardGive specific examples Use clear terms Make clear comparisons (how are they both similar a different) Use diagrams/models/graphs t demonstrate your understanding Use the process - identify, explain, connect and, if possible make greater connections/analogies etc. 1) Using either cellular respiration or photosynthesis describe the use of energy and its transformations order to proceed from products to reactants. Explain why the equation for your chosen reaction is misleading for a student learning the process, and also why it is crucial that the transformations happen the way they do and not as a simple combustion reaction: (use of diagrams and/or molecular structures to aid your explanation is highly encouraged) a) Energy Transformations: b) Equations: C6H1206(s) + 602(g) ➡ 6CO2(g) + 6H₂O(g) OR 6CO2(g) + 6H₂O(g) ➡ CH1206(s) + 602(g) c) Combustion reaction: (use of diagrams and/or molecular structures to aid your explanation is highly encouraged)arrow_forward
- *Which of the following statements about allosteric enzymes is NOT true? Question 10 options: - They are regulated by positive and negative modulators - They have more than one native conformation - Their activity is altered by phosphorylation - They often catalyse a reaction at the beginning of a metabolic pathway please explain than give answerarrow_forwardMetabolic pathway characteristics: a. Give one example of an amphibolic pathway. b. What characteristic(s) of this pathways make it amphibolic? c. Provide two specific examples of the fate of a metabolite in the pathway as support for your answer in (b). ***please help with this hw problem!!!***arrow_forwardConsider two enzymes catalyzing two reactions (A --> B --> C ) in a metabolic cascade with their properties summarized below: Keg (for reaction) Enzyme Reaction KM Kcat / KM 102 M-1s-1 108 M-1s-1 1 A --> B 1 1 mM 2 B --> C 10 10 mM Initial concentrations are [A] = 0.1 mM and [B] = [C] = 0 and both enzymes are present at concentrations of 1 mM. After waiting for 1 ms, the concentrations of A, B, and C are measured. How do you expect the concentrations to be ordered? O [B] > [A] > [C] O [C] > [B] > [A] O [A] > [B] > [C] O [A] > [C] > [B] [C] > [A] > [B]arrow_forward
- Using good details, compare and contrast the pairs of different biochemical reactions. Create your own comparing and contrasting map similar to the one below to show your understanding. Dehydration Synthesis vs. Hydrolysis Phosphorylation vs Hydrolysis Phosphorylation vs Decarboxylation Oxidation vs Reduction.arrow_forwardThe following diagram shows reaction curves for aspartate transcarbamoylase (ATCase) with carbamoylphosphate and different concentrations of aspartate, in the absence of ATP (curve 1) and presence of ATP (curve 2). What do the shapes of the curves tell us about the ATCase enzyme? 2 جر [aspartate] It binds substrate through a sequential mechanism. It binds substte cooperatively. It obeys Michaelis-Menten kinetics. It binds substrate through a concerted mechanism.arrow_forwardOxidation-reduction reactionn a biochemical pathway, three ATP molecules are hydrolyzed. The endergonic reactions in the pathway require a total of 17.3 kcal/mole of energy to drive the reactions of the pathway. What is the overall change in free energy of the biochemical pathway? Is the overall pathway endergonic or exergonic?s can involve a wide variety of molecules. Why are those involving hydrogen and oxygen of paramount importance in biological systemsarrow_forward
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