Which enzyme in ß-oxidation extracts two electrons from the fatty acid, resulting in the eventual generation of 1.5 ATP each time that it catalyzes a reaction? O Acyl-CoA dehydrogenase O succinate dehydrogenase OL-hydroxyacyl-CoA dehydrogenase O Enoyl-CoA hydratase
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- Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited by· NIADH. Pyruvate dehydrogenase is inhibited by AΤΡ. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.Using the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved residues in slightly different positions can change the catalytic rate of reaction.Step 2 of B-oxidation involves a reaction with chemistry characterized as a dehydration. B-Oxidation is shown below. H HO || || C-C-S – CoA FAD но R-CH2- C Acyl-CoA dehydrogenase H-C-C -S- CoA Acetyl-CoA Fatty acyl-CoA H FADH2 - CH2 - -c-S- CoA R- Thiolase Fatty acyl-CoA shortened by two carbons COA-SH H. он Successive cycles R-CH2-C-C- -C-S- CoA R– CH2 C=C-C-S-CoA H B-Ketoacyl-Co.A trans-A²Enoyl-CoA NADH + H* H,0 H H L-Hydroxyacyl-CoA dehydrogenase Enoyl-CoA hydratase R- CH,-c-c-C- S-CoA Но H NAD+ L-B-Hydroxyacyl-CoA True O False
- Which enzyme is used for both the synthesis and breakdown of acetoacetate? thiolase O HMG-CoA synthase OB-hydroxybutyrate dehydrogenase O B-Ketoacyl-CoA transferaseWhich of the following is NOT part of the multi-enzyme complex of fatty acid synthase? O enoyl-ACP reductase O acetyl CoA carboxylase O 3-hydroxybutyrylACP-dehydratese O B-ketoacyl-ACP reductaseWhat is the final reaction in the final round of fatty acid synthase? Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP Reductase
- In beta-oxidation, which cofactor is required the for second oxidation reaction (conversion of beta-hydroxyacyl-CoA to beta-ketoacyl-CoA)? NAD+ water FAD CoA-SHWhat enzyme(s) is/are specifically required for the oxidation of a Aeven monounsaturated fatty acid? (select all that apply) O Methylmalonyl CoA Mutase O enoyl-CoA Hydratase 43-enoyl-CoA isomerase Thiolase 2,4-Dienoyl-CoA Reductase OPropionyl-CoA carboxylaseAlthough glucose cannot be formed from acetyl-CoA, triglycerides can enter the glycolytic pathway via which process? O Acetyl-CoA → oxaloacetate → phosphoenolpyruvate O Palmitoyl-CoAB- ketoacyl-CoA → a-ketoglutarate O Glycerol → DHAP Acyl-CoA glucose
- Identify the Krebs cycle enzyme that consumes a 3-carbon substrate molecule, producing a 2- carbon product molecule (attached to acetyl-CoA), along with NADH, and one molecule of CO2. succinyl CoA synthetase a-ketoglutarate dehydrogenase pyruvate dehydrogenase isocitrate dehydrogenase malate dehydrogenaseThe following reaction is a vitamin B12-dependent reaction that proceeds via a mechanism analogous to that of the methylmalonyl-CoA mutase reaction. H Н4 H 1 H3N 2 H `H H HO b H H5 Identify which atoms in the product(s) correspond to the numbered atoms in the reactant. Atom a corresponds to atom Atom b corresponds to atom Atom c corresponds to atomWhat is(are) the product(s) of the thiolase reaction involving a sixteen carbon ß-ketoacyl substrate and CoASH? O A 14 carbon acyl-CoA molecule and acetyl-CoA O An 18 carbon acyl-CoA molecule and acetyl-CoA O acetoacetyl coA O An 18 carbon acyl-CoA molecule