Gluconeogenesis (work only on the enzymes that are not shared with the glycolytic pathway) AG (kJ/mol) Enzyme EC Reaction Tricarboxylic Acid Cycle (include pyruvate dehydrogenase complex) = KREBS EC Enzyme Pyruvate dehydrogenase complex 1.2.4.1 AG (kJ/mol) Pyruvate Acetyl-S-CoA +-33.4 CO₂ Reaction Cofactors Cofactors Lipoic acid, thiamine pyrophosphate, FAD, NAD, S-CoA. Coenzyme A. Regulation Regulation Inhibited by NADH + H, ATP, acetyl- Stimulated by NAD+, AMP and coenzyme A Notes Notes PDH deficiency: ataxia, poor muscle tone, high lactate, etc. (GHR, 2012)

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter19: The Tricarboxylic Acid Cycle
Section: Chapter Questions
Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...
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Please help fill out the metabolic Pathway table of Gluconeogenesis and Tricarboxylic by listing its enzymes and functions

Gluconeogenesis (work only on the enzymes that are not shared with the glycolytic pathway)
AG
Enzyme
Reaction
(kJ/mol)
EC
Tricarboxylic Acid Cycle (include pyruvate dehydrogenase complex) = KREBS
Enzyme
EC
Pyruvate dehydrogenase complex 1.2.4.1
Reaction
AG
(kJ/mol)
Pyruvate Acetyl-S-CoA + -33.4
CO₂
→
→
Cofactors
Regulation
Cofactors
Lipoic acid, thiamine
pyrophosphate, FAD, NAD, S-COA
Coenzyme A.
Regulation
Inhibited by NADH+H, ATP, acetyl-
Stimulated by NAD+, AMP and
coenzyme A
Notes
Notes
PDH deficiency: ataxia, poor muscle
tone, high lactate, etc. (GHR, 2012)
Transcribed Image Text:Gluconeogenesis (work only on the enzymes that are not shared with the glycolytic pathway) AG Enzyme Reaction (kJ/mol) EC Tricarboxylic Acid Cycle (include pyruvate dehydrogenase complex) = KREBS Enzyme EC Pyruvate dehydrogenase complex 1.2.4.1 Reaction AG (kJ/mol) Pyruvate Acetyl-S-CoA + -33.4 CO₂ → → Cofactors Regulation Cofactors Lipoic acid, thiamine pyrophosphate, FAD, NAD, S-COA Coenzyme A. Regulation Inhibited by NADH+H, ATP, acetyl- Stimulated by NAD+, AMP and coenzyme A Notes Notes PDH deficiency: ataxia, poor muscle tone, high lactate, etc. (GHR, 2012)
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