Prostate cells usually require testosterone and other androgens to survive. But some prostate cancer cells thrive despite treatments that eliminate androgens. One hypothesis is that estrogen, often considered a female hormone, may be activating genes normally controlled by an androgen in these cancer cells. Part A Choose the experiments to test this hypothesis. Select all that apply. O Look for evidence of transcription or translation of the genes of interest in the absence of androgens. O Look for the presence of an estrogen-receptor complex in the nuclei of prostate cancer cells. O Use a treatment to eliminate estrogen, and note the effect on the proliferation of prostate cancer cells. O Look for evidence of transcription or translation of the genes of interest in the presence of androgens. O Look for the presence of an estrogen-receptor complex in the nuclei of normal prostate cells. O Look for the presence of G protein-coupled receptors in prostate cancer cells.

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter16: Regulation Of Gene Expression
Section: Chapter Questions
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SCIENTIFIC INQUIRY
Prostate cells usually require testosterone and other androgens to survive. But some prostate cancer cells thrive despite treatments that eliminate androgens. One hypothesis is that
estrogen, often considered a female hormone, may be activating genes normally controlled by an androgen in these cancer cells.
Part A
Choose the experiments to test this hypothesis.
Select all that apply.
Look for evidence of transcription or translation of the genes of interest in the absence of androgens.
Look for the presence of an estrogen-receptor complex in the nuclei of prostate cancer cells.
Use a treatment to eliminate estrogen, and note the effect on the proliferation of prostate cancer cells.
Look for evidence of transcription or translation of the genes of interest in the presence of androgens.
Look for the presence of an estrogen-receptor complex in the nuclei of normal prostate cells.
Look for the presence of G protein-coupled receptors in prostate cancer cells.
Transcribed Image Text:SCIENTIFIC INQUIRY Prostate cells usually require testosterone and other androgens to survive. But some prostate cancer cells thrive despite treatments that eliminate androgens. One hypothesis is that estrogen, often considered a female hormone, may be activating genes normally controlled by an androgen in these cancer cells. Part A Choose the experiments to test this hypothesis. Select all that apply. Look for evidence of transcription or translation of the genes of interest in the absence of androgens. Look for the presence of an estrogen-receptor complex in the nuclei of prostate cancer cells. Use a treatment to eliminate estrogen, and note the effect on the proliferation of prostate cancer cells. Look for evidence of transcription or translation of the genes of interest in the presence of androgens. Look for the presence of an estrogen-receptor complex in the nuclei of normal prostate cells. Look for the presence of G protein-coupled receptors in prostate cancer cells.
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