The force of contraction can be changed by: Not by the parasympathetic NS. (at least, not the ventricles). muscarinic ACh receptors. Activation of the receptors leads to decreased Ca2+ entry and increased K+ entry in ventricles. ✔ Beta1 adrenergic receptors. Increasing CAMP leads to increases in PKA, which increases sarcoplasmic calcium by opening VG Ca+ channels for a longer time, opening SR Ca2+ channels, and increasing the rate of Ca2+ removed by SERCA pumps. Beta2 adrenergic receptors. Increasing CAMP leads to increases in PKA, which increases sarcoplasmic calcium by opening VG Ca+ channels for a longer time, opening SR Ca2+ channels, and increasing the rate of Ca2+ removed by SERCA pumps.
The force of contraction can be changed by: Not by the parasympathetic NS. (at least, not the ventricles). muscarinic ACh receptors. Activation of the receptors leads to decreased Ca2+ entry and increased K+ entry in ventricles. ✔ Beta1 adrenergic receptors. Increasing CAMP leads to increases in PKA, which increases sarcoplasmic calcium by opening VG Ca+ channels for a longer time, opening SR Ca2+ channels, and increasing the rate of Ca2+ removed by SERCA pumps. Beta2 adrenergic receptors. Increasing CAMP leads to increases in PKA, which increases sarcoplasmic calcium by opening VG Ca+ channels for a longer time, opening SR Ca2+ channels, and increasing the rate of Ca2+ removed by SERCA pumps.
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter9: Cardiac Physiology
Section: Chapter Questions
Problem 12RE
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