50. In the small intestines, cells are responsible for transporting glucose into the cell from the small intestines interior space. The transporter responsible for that is the glucose/sodium transporter. The following chart shows the concentrations of sodium and glucose inside and outside the cell. Na Glucose Extracellular 140mM 0.2mM Intracellular 12mM 3mM A. Can these conditions be used to transport glucose inside the cell? Explain.
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- When blood glucose level rises, the pancreas secretes insulin, and as a result blood glucose level declines. When blood glucose level is low, the pancreas secretes glucagon, and as a result blood glucose level rises. Such regulation of blood glucose level is the result of A reproduction thermal regulation community homeostasis 2,279 12 tv N MacBook Air DII DD F1 F2 F3 F4 F5 F6 F7 F8 F9 F10 F1 @ %23 24 2 6. %3D * COCan't see this image? Please see this file:Online Module 2A Q5.pdf Consider the scenario depicted below: A Transporter A Transporter B Transporter C B Transporter D C D Electrochemical gradient: high high low Which transporter (D or E) represents how the Na+/Glucose transporter allows for glucose uptake into intestinal cells? Note that the outside and inside of the cell are not labeled. II low low high121 11) The table below compares and contrasts carrier protein pumps with clathrin-dependent receptor-mediated endocytosis. Fill in the empty spaces of the table with the appropriate answer Clathrin- Carrier protein dependent receptor mediated endocytosis pump Involvement of multiple types of proteins? (Yes/No) Involvement of ATP? (Yes/No) Involvement of dynamin? (Yes/No) Membrane proteins involved are specific for only a small number of different types of substances? (Yes / No) Possible direction of movement of transported molecules (Into cell/Out of cell/Both) Requires formation of a vesicle? (Yes/No)
- O Att Intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Nat-glucose symporter. Recall that the Nat concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" transport of two Nat ions into the cell to the "uphill" transport of glucose into the cell. If the Nat concentration outside the cell ([Na lout) is 161 mM and that inside the cell ([Na* Jm) is 17.0 mM, and the cell potential is -50.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C. What is the maximum ratio of (glucose] to [glucoselout 10.62 kJ AG gluc mol that could theoretically be produced if the energy Incorrect coupling were 100% efficient? O 1.13 8.24 3800 2.6 x 10 IncorrectIntestinal epithelial cells pump glucose into the cell against its concentration gradient using the Na-glucose symporter. Recall that the Na* concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" transport of two Na* ions into the cell to the "uphill" transport of glucose into the cell. If the Nat concentration outside the cell ([Na lout) is 141 mM and that inside the cell ([Na* lin) is 19.0 mM, and the cell potential is -52.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C. AGglac 9.63 Incorrect kJ mol What is the maximum ratio of [glucose), to [glucose)out that could theoretically be produced if the energy coupling were 100% efficient? O 2700 1.13 3.7 x 10- 7.90In the stomach, parietal cells are responsible for the formation of the gastric juice. During acid secretion, the pH in the stomach is estimated to be pH = 2, whereas parietal cells maintain an intracellular pH =7.35. The transmembrane potential of parietal cells is typically -70 mV. Body temperature 37°C. 1) Calculate the proton gradient concentration across the parietal membrane 2) Calculate the free energy change associated with the secretion of 1 mole of H* 3) Do you think that Ht transport can be driven by ATP hydrolysis at the ratio of one molecule of ATP per H* transported? You can use your textbook or other sources to check AG for ATP hydrolysis 4) If H* where free to move back to into the cell, calculate the membrane potential that would be required to prevent them to do so
- Intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Na+– glucose symporter. Recall that the Na+ concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" transport of two Na+ ions into the cell to the "uphill" transport of glucose into the cell. If the Na+ concentration outside the cell ([Na+]out) is 163 mM and that inside the cell ([Na+]in) is 21.0 mM, and the cell potential is −54.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C.Describe the symport process by which cells lining the small intestine import glucose. What ion is responsible for the transport, and what two particular features facilitate the energetically favored movement of this ion across the plasma membrane?Intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Nat-glucose symporter. Recall that the Na+ concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" transport of two Na+ ions into the cell to the "uphill" transport of glucose into the cell. If the Na+ concentration outside the cell ([Na+]out) is 155 mM and that inside the cell ([Na+ lin) is 21.0 mM, and the cell potential is -52.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C. AGgluc = kJ mol What is the maximum ratio of [glucose] in to [glucose]out that could theoretically be produced if the energy coupling were 100% efficient? O 2700 7.89 O 1.14 3.7 x 10-4
- Name the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3 −) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms.What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?Movement of glucose from one side to the other side of the intestinal epithelium is a major example of transcellular transport. How does the Na+/K+ ATPase power the process? Why are tight junctions essential for the process? Why is localization of the transporters specifically in the apicalor basolateral membrane crucial for transcellular transport? Rehydration supplements such as sport drinks include a sugar and a salt. Why are both important to rehydration?Intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Na*-glucose symporter. Recall that the Na+ concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" transport of two Na+ ions into the cell to the "uphill" transport of glucose into the cell. If the Na+ concentration outside the cell ([Na* lout) is 147 mM and that inside the cell ([Na+]in) is 17.0 mM, and the cell potential is -54.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C. AG gluc kJ mol What is the maximum ratio of [glucose]in to [glucose] out that could theoretically be produced if the energy coupling were 100% efficient? 1.13 2.3 × 10-4 8.36 4300