Of Aspirin, ethanol, acetaminophen, ethyl acetate, hexane, and water which could go undetected during HPLC analysis, but could result in a lower than expected melting point, why are they not detected by HPLC analysis

Of Aspirin, ethanol, acetaminophen, ethyl acetate, hexane, and water which could go undetected during HPLC analysis, but could result in a lower than expected melting point, why are they not detected by HPLC analysis

Principles of Instrumental Analysis

7th Edition

ISBN:9781305577213

Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Chapter33: Automated Methods Of Analysis

Section: Chapter Questions

Problem 33.5QAP: Give the advantages and disadvantages of sequential injection analyzers compared to traditional flow...

See similar textbooks

Related questions

Q: How can you use ion exchange Chromatography to de-ionize water? Please shortly write at your own…

A: Answer - Ion exchange Chromatography - Ion chromatography (or ion-exchange chromatography)…

Q: Column Chromatography works by the same principle as TLC however the silica gel is not plated on a…

A: Note : Compound A is more soluble in mobile phase. Therefore less polar and having higher Rf.…

Q: All three of these are gas chromatography runs from my sample. I'm trying to figure out what it…

A: To find the reason for varied retention times and intensities

Q: Explain in depth why you had to use ethanol and water to elute the compounds for column…

A: Concept: Column chromatography: Column chromatography is a technique in chemistry to isolate a…

Q: Help please : When comparing HPLC with Gas Chromatography , Gas Chromatography analysis may require…

A: Chemical derivatization is a step in gas chromatography in which a compound is chemically…

Q: We use reverse phase column chromatography with a non-polar C18 stationary phase and a mixture of…

Q: The key to a successful HPLC procedure is good sample separation which is represented by a clean…

A: In this question, we have to choose the correct option from the given options.

Q: What are the different melting point apparatus that are available for routine analysis? Describe…

A: A melting point apparatus measures the melting Point of a given substance.

Q: Chromatographic analysis using gas-liquid chromatography with a 40-cm packed column gave the…

A: Given, Compound Retention time, min…

Q: Internal standard. When 1.06 mmol of 1-pentanol and 1.53 mmol of 1- exanol were separated by gas…

A: Gas chromatography (GC) is an analytical technique used to separate the chemical components of a…

Q: Which statement is true? Statement 1: Since tiny amounts of material are exposed on an open…

A: The answer of the above question is given in step 2

Q: Study the chromatograph (below) of a mixture of Compounds A and B, run on the GCs in the teaching…

A: Chromatography is an analytical technique that is used for separating a mixture of chemical…

Q: Iman has a mixture of two compounds A and B. A is a protein, and B is a lipid. He plans to separate…

A: Apparatus diagram

Q: Consider the following statements as they apply to gas chromatography. Decide if each is true or…

A: 1. Temperature programming is often employed for samples with a wide range of boiling points.…

Q: In ion-exclusion chromatography, ions are separated from nonelectrolytes (uncharged molecules) by an…

Q: What are the different parts of Flash Column Chromatography? Please answer at your own words

A: Flash column chromatography is a method in which chemical mixtures are separated and purified by…

Q: As distillation method is used to seperate a homogenous mixture, which kind of mixtures…

A: Chromatography is a technique that is used for separating the components in a mixture. Separation is…

Q: We separated a mixture of sodium carbonate and calcium chloride using Gravity Filtration.…

A: A question based on analytical separation that is to be accomplished.

Q: Classify the stationary phases based on whether they are commonly used in reversed-phase liquid…

Q: Which of the following is not a method for measuring reaction rates? A) total pressure B) thin layer…

A: A multiple choice question based on measuring reaction rate, which is to be accomplished.

Q: How would the Rf values change if you used pure dichloromethane (no methanol) as the mobile phase…

A: The dielectric constant for methanol is 30 and that of Dichloromethane is 8.3

Q: Gestation time arrangement of Hegran, Hexanol, and Benzene compounds in the reverse phase of column…

A: A question based on analytical process that is to be accomplished.

Q: A mixture of the follwoing compounds was separated by HPLC with a stationary nonpolar phase and a…

A: The polarity of acid, alkane and ether is in the order: acid > ether > alkane

Q: Describe how you would prepare a sample for TGA analysis if it were provided in the form of: (i)…

A: Thermogravimetric analysis (TGA) of polymers is conducted to measure weight changes as a function of…

Q: The following data were obtained by gas-liquid chromatography on a 40-cm packed column: Compound tr,…

A: To solve this problem, we will need the following relations regarding gas-liquid chromatography : 1.…

Q: a) Compounds with low boiling points tend to spend less time in the gaseous state than compounds…

A: The questions are based on the concept of gas chromatography. it is an instrumental technique of…

Q: 4. When performing a melting point on solid compound using a melting point apparatus, two melting…

Q: In a chromatographic analysis, a solution containing 0.0837M toluene and 0.0666M xylene resulted in…

A: Response factor can be represented as

Q: For each of the following statements, answer TRUE or FALSE and explain your answer briefly. It…

A: True Potassium Dichromate solutions (235 - 430 nm)The most widely recognised reference material for…

Q: 1. What are the features of samples/compounds that allow them to be suitable for Gas Chromatography…

Q: Match column A with column B. v Mobile phase: NON-POLAR Stationary phase: NON-POLAR v mobile phase -…

Q: 4. When performing a melting point on a solid compound using a melting point apparatus, two melting…

A: Note - Since you have asked multiple questions, we will solve the first question for you. If you…

Q: For thin layer chromatography, why should a piece of filter paper that is moistened with the…

A: Purpose of the Filter Paper in the Thin-Layer Chromatography :- Filter paper is placed in the…

Q: Thin‑layer chromatography (TLC) can be used as a preliminary identification method for many…

A: Given that., Distance traveled by the spot from bottom = 3.52 cm Distance travel by mobile phase =…

Q: If there is a mixture of more volatile and less volatile substances and are to be separated through…

Q: Please choose an appropriate technique(s) to separate following compounds (it can be one, more than…

A: We can see the difference in boiling point of both that is the Phenol and Toluene.

Q: Chromatographic analysis using gas-liquid chromatography with a 40-cm packed column gave the…

Q: In your own words, discuss the reason why stray light should be minimized. How does stray light…

Q: True or False? In column chromatography the solvent moves up and through the adsorbent by capillary…

A: Answer :- 8) False 9) y-adaptor and condenser…

Q: In the second paragraph you should define and describe the process of gas chromatography. In this…

A: A diluted sample in used in gas chromatography because this helps in establishing a proper…

Q: Determine the order of inhibition time of hexane, hexanol and benzene compounds in the reverse phase…

A: Given compounds: Hexane, hexanol and Benzene. To determine: The order of Inhibition time in Reverse…

Q: best choice of mobile phase in a thin layer chromatography experiments is: Group of answer choices…

A: The correct option are as follows:

Q: You were analyzing a mixture of volatile solvents using Gas Chromatography and found out that two…

A: Chromatography is the method for the separation of a mixture with very high resolution, which is an…

Q: Why is gas-solid chromatography not used as extensively as gas-liquid chromatography

A: Given : Gas-solid chromatography is not used as extensively as gas-liquid chromatography.…

Q: Explain each in 5 sentences Paper Chromatography- Thin layer Chromatography- Column…

A: Chromatography is used to seprate the mixture and to purify the compounds. First three given are the…

Q: One of the main differences between TLC and column chromatography is the direction in which the…

A: Purification is one of the key step in the isolation of organic or inorganic compounds. Different…

Q: C. A cube of dimensions 10 cm x 10 cm x 10 cm has mass of 1.90 Kg a water content w = 15%. The…

A: This question has multiple parts . As per the guidelines we are allowed to provide solution of…

Q: Two group of students wish to analyse caffeine content in tea samples. Group 1 performed the…

A: Chromatography is the laboratory technique for the separation and isolation of a variety of samples…

Q: Use a suitable model to explain how separation and identification of a mixture of organic compounds…

A: The mixture indicates the presence of two or more components of a substance in nonspecified molar…

Q: veloped a chromatogram and found that the eluent front traveled 69 mm and the Zinc cation traveled…

A: A student developed a chromatogram and found that the eluent front traveled 69 mm and the Zinc…

Question

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

introduction

VIEW

Explanation

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Give the advantages and disadvantages of sequential injection analyzers compared to traditional flow Injection analyzers.
In molecular exclusion (size exclusion) chromatography, the molecules have the longest retention times. a) the larger molecules b) the smaller molecules
Explain why TLC cannot be used for some volatile low molecular weight substances such as toluene.
A young researcher set out to develop a method for quantifying the polycyclic aromatic hydrocarbon (PAH) content in a contaminated soil sample using open tubular gas chromatography. During the initial stages of method development, the researcher was unable to separate the early eluting compounds, anthracene and naphthalene, with baseline resolution. Select the possible modifications the researcher could make to improve the resolution. use a column with a smaller inner diameter decrease the column length increase the stationary phase thickness increase the temperature choose a different stationary phase
Can paper chromatography be used to separate and identify very volatile substances? Why? Please explain comprehensively.
Table 1: Selected phytocomponents identified in the plant extract. Retention time, min Name of Compound 10.767 Benzaldehyde 15.790 Azulene 16.002 1-Piperazinecarboxaldehyde 17.935 Phthalan 20.731 2-methoxy-1,3,4-trimethybenzene 24.028 Methylesterpentanoic acid 26.993 Tetradecamethylcycloheptasiloxane 31.753 Hexadecamethyl Cyclooctasiloxane If GC is combined with MS, what data you will add as the 3rd column in Table 1 above. Fill in that data for each of the select identified phytocomponents.
Differentiate normal phase chromatography from reverse phase chromatography. From which of the two governs the video demonstration in TLC and paper chromatography? How do you say so?
A student researcher performed a chromatographic separation of caffeine and aspartame. The retention time for caffeine, tc, was found to be 209.6 s with a baseline peak width, w., of 14.4 s. The retention time for aspartame, ta, was 260.0 s with a baseline peak width, wa, of 21.2 s. The retention time for the unretained solvent methanol was 49.2 s. Calculate the average plate height, H, in micrometers for this separation, given that it was performed on a 22.1 cm long column. H = um %3D Calculate the resolution, R, for this separation using the widths of the peaks. R = Calculate the resolution if the number of theoretical plates were to increase by a factor of 2. R2N =