In panel B, the effector induces a conformational change that inhibits enzyme activity.The effector regulates enzyme activity by binding to the active site.In panel A, the effector induces a conformational change that inhibits enzyme activity.In panel B, the effector induces a conformational change that enhances enzyme activity.The effector regulates enzyme activity by binding to the substrate.In panel A, the effector induces a conformational change that enhances enzyme activity. In the diagram below, the orange circle represents an effector and the dark purple shapes(both the diamond and the rod) represent a substrate.Based on this information, which statement(s) about the diagram is/are true? Select allthat apply.AAllostericsiteBAllostericsiteCAllostericsiteAllostericeffectorActive siteAllostericeffectorActive site,AllostericeffectorNovelbindingsite

An allosteric effector, also referred to as an allosteric regulator, is defined as a molecule which…

Answered: In the diagram below, the orange circle…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Terms can be used once, more than once, or not at all. Submit dCTP GMP AMP GTP dTTP activation inhibition dGTP My Answers Give Up UTP + Gln + ATP → CTP + Glu+ ADP + P₁. Cofactor: dCMP + H₂O →→→→DUMP + NH3. Cofactor: CDP+ [2H] → dCDP+ H₂O. Cofactor: Effect: Effect: Effect: Reset Help
One way of identifying a drug target in a complex cellular extract is to use an affinity approach, i.e. fix the drug to a resin (agarose etc) and use it to "pull down "" the target from the extract. What potential problems do you think may be encountered with attempting this approach?
The bacteria that you are growing to express biochemisfunase are resistant to ampicillin, so you keep ampicillin in your media to prevent contamination from other bacterial strains. You find a tube of ampicillin in the lab freezer that says “2000x AMP” on the lid, which indicates that it is 2000 times more concentrated than what you need (i.e., a concentration of 1x ampicillin in your media). How much of the 2000x ampicillin stock would you add to your 1.0-L culture to get a final concentration of 1x ampicillin?
the 10 mg/mL sample of lysozyme shows a lower activity than 2mg/mL lysozyme sample (refer to the graph shown below). It is potentially due to Inefficiency of lysozyme at high concentrations. Highest concentrated lysozymes do have lowest activity. Loss of data due to user inefficiency. Loss of data due to spectrophotometer inefficiency.
You have an order for 1 gram of Cefazolin in D5W 100 ml. You have added 5 ml of sterile water to the 1 gram vial to reconstitute powder. However the recommended manufacturer’s diluent amount is 10 ml of sterile water for a final concentration of 100 mg/ml. How would reconstituting the vial with 5 mls affect the concentration and the final calculated dose. Please answer with explanation ASAP. I will really upvote. Thanks
From a medicinal chemistry (and a pharmacologist) perspective, functional groups provide specific properties and behaviors that allow drug molecules to exert their desired PD and PK effects. The key point here is that each individual group within a drug molecule can serve to provide one or more specific roles, tasks, or functions. The following table summarizes a series of drug discovery lead optimization for targeting a certain renal disease. Explain the basis for changing the R- functionality at the para- position. Please explain in as much detail as you need and by using scientific justifications, which one of the 4 candidates (526-529), presents the most viable investigational drug candidate, given the information provided below? N- `N' 'N' R- Drug Code R IC30 (nM) Half-Life (tı2), Minutes 526 CH;O 104 6 527 CF;0 1110 95 528 CH;CH, 11 <5 529 CH,CF, 14 96
Give detailed Solution with explanation needed (don't give Handwritten answer, )
Give detailed Solution with explanation (don't give Handwritten answer, )
Concentrations in biochemical systems are often very dilute. Consequently, scientific notation and logarithms are often used to express concentrations. In scientific notation, numbers are expressed as coefficient x 10" To convert a number to scientific notation, proceed as follows: 1. Move the decimal place so that there is one digit in front of the decimal. 2. Account for the moved decimal in the value of x. If the decimal moved to the right, x is negative; if it moved to the left, x is positive. A logarithm is basically an exponent. Unless otherwise indicated, a logarithm is the a of 10". The numbers after the decimal point are significant; the number before the decimal just identify the location of the decimal point for the number. Notice that it is easy to estimate a logarithm from scientific notation; it's the exponent! Logarithms are commonly used to express the concentration of H. The pH is defined as pH= log (In), where the base number is 2.303. The same general rules as logs…
1/v 1/[S] Compound I is a substrate for the enzyme reverse transcriptase and compounds Il and lll are inhibitors. The inhibition plots for each compound are Illustrated above. The line labeled E is the enzyme with substrate alone (no inhibitor present). Answer the following questions by filling în the blanks. Line A most likely belongs to compound because it is a inhibitor. Line B belongs to compound because it is a inhibitor.
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A vial of Doxorubicin reads 0•5g per vial. Instructions say to reconstitute each 12mg with 2•5ml of NS. How many ml of NS will be needed to reconstitute the vial of the recommended concentration? please show working

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