Fill in the missing uppercase letters The map distances for four linked genes are as follows: A-B = 22 cM, B-C = 7 cM, C-D = 9 cM, B-D = 2 CM, A-D = 20 CM. The order of the four genes is ◆
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- In each of these diagrams (A-D) homologs are shown as the same size and color. A 810 19 C B Which of these could be describe as 2n=4? [Select] Which of these could be describe as 2n=2? Which of these could be describe as 1n=2? Which of these could be describe as 2n=46? Which of these could be describe as 1n=3? Which of these could be describe as 2n=6 ? [Select] [ Select] [ Select] [Select] [Select]A geneticist examines an ear of corn in which most kernels are yellow, but he finds a few kernels with purple spots, as shown here. Give a possible explanation for the appearance of the purple spots in these otherwise yellow kernels, accounting for the different sizes of the spots.EC1. In drosophila the cw (curly wings) gene and eb (ebony body) genes are found on the same chromosome 20 map units apart. A cross was made between an ebony bodied parental strain and a curly winged parental strain and the F1’s were test crossed. a) What are the genotypes of the parental strains? b) What are the genotypes of the F1’s? c) What is the genotype of the tester strain? d) What progeny phenotypes and genotypes do you expect, and in what proportions? For phenotypes use the mutant phenotype for any that the flies have, and wild-type if they have none. EC2. Here is a tetrad produced by mating a H Y strain to an h y strain. a) What is the tetrad type? b) What has recombined with what? EC3. In corn, a dihybrid for the recessive genes a and b is test-crossed. The distribution of the phenotypes is as follows: A B 122A b 118a B 81a b 79 a) Do the genes appear to be sorting independently? Look at map units here. b) Test your hypothesis with a chi-squared test.
- A geneticist discovers that a girl with Down syndrome has a Robertsonian translocation involving chromosomes 14 and 21. If she has an older brother who is phenotypically normal, what are the chances that he is a translocation carrier?Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?The gene controlling ABO blood type and the gene underlying nail-patella syndrome are said to show linkage. What does that mean in terms of their relative locations in the genome? What does it mean in terms of how the two traits are inherited with respect to each other?
- Please label the tetrad type in the table as PD (parental ditype), NPD (non parental ditype) or T (tetratype) and answer the following questions a) Are the genes linked? Please explain SPECIFICALLY how you can distinguish between linked and unlinked genes in this instance. b) If the two genes are linked, calculate the % recombination between ser and thr. Show the formula used, as well as all of your calculations. c) Draw a single map illustrating the arrangement of the two genes on the chromosome with respect to each other and to the centromere of the chromosome. Make sure to map ALL three distancesDraw all possible linkage maps for these three genes.Cross ou An organism has the genotype a"g*/a"g*;g"f"/q+t";rth*/rth*. Indicate the correct genes/ alleles at all the positions numbered 1-12 in the image below such that the diagram accurately represents the genotype of this organism. Note: assume the first chromosome in each pair shown in the genotype is the top chromosome shown in the diagram. 1 2 a gene ggene 3 4 : 5 2 9 gene fgene 7 8. | 10 rgene hgene 11 12 Only place the genes/ alleles you need. You will not need them all. You may need to use some more than once. • gene / allele 1 a- : gene / allele 2 g+: gene / allele 3 a- : gene / allele 4 g+ • gene / allele 5 q- : gene/ allele 6 f- ; gene / allele 7 q+: gene / allele 8 f- • gene / allele 9 r+; gene / allele 10 h+ ; gene / allele 11 r+ gene / allele 12 h+ a+ f+ f- g+ g- ||h+|| h- || q+|| q- r- a- r+ 3.
- CIUSS O An organism has the genotype a g*/a"g*; qf"/q+f*;r+h+/rth*. Indicate the correct genes/ alleles at all the positions numbered 1-12 in the image below such that the diagram accurately represents the genotype of this organism. Note: assume the first chromosome in each pair shown in the genotype is the top chromosome shown in the diagram. 1 i 2: a gene g gene 6. q gene fgene 7 8. | 10 r gene h gene 12 Only place the genes/ alleles you need. You will not need them all. You may need to use some more than once. • gene / allele 1 a- ; gene / allele 2 g+ ; gene / allele 3 a- gene/allele 4 g++ • gene / allele 5 q- ; gene / allele 6 f- gene / allele 7 q+; gene / allele 8 f- gene / allele 9 r+; gene / allele 10 h+ gene / allele 11 r+ gene / allele 12 h+ a+ a- f+ f- g+ g- h+ h- q+ q- r+ r- 2.The diagram below is a linkage map. Choose the answer that best describes the relationship between each of the pairs of genes listed. Are they in the same linkage group or different? Are they linked genes or unlinked? R-S? E-P? E-S? L-B? X-L? R-X? P-B? X-B? Choose from the following: Same linkage, different group Different linkage groups, linked Same linkage group, unlinked Different linkage groups, unlinked2. You are making a genetic map and use a cross to measure the distance between genes H and J as 40cMand the distance between J and M as 20cM. When you measure the distance between genes H and M, you get 50 cM. Do the following (A-C). (A) Draw and label a map of genes H, J, and M. (B) What is the genetic distance between genes H and M? How do you know? (Answer in 1 sentence) (C) Complete the table (right). For each pair of genes, write “yes” or “no” to indicate whether the pair of genes are“linked genes” and/orpart of the same“linkage group”.