1. Which one of the following statements correctly defines the concept of gene expression? Gene expression is the process J. used to transfer information from RNA to DNA. K. that controls the M phase of the cell cycle. L. by which information from a gene is used in the synthesis of a functional gene product. M. where specific parts of the DNA is changed into protein.
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- 4. Which or which (can select more than one alternative) of the control methods of genetic expression in eukaryotes NOT USED in prokaryotic cells?to. control how often a gene is expressedb. control how an mRNA is processedc. control which mRNA is exported from the nucleus to the cytosold. control which mRNA is translated to proteins in the ribosomeand. control how quickly proteins are destroyed once synthesized 5. Unlike DNA that usually forms a helical structure, different RNA molecules assume bends in a wide variety of 3D shapes. This is due to :to. RNA contains uracil and ribose as sugarb. the bases in the RNA cannot form hydrogen bonds with each otherc. nucleotides in RNA have a different chemical structure than they have in DNAd. Although RNA is single-stranded, complementary bases can pair with each other. 6. Viruses consist of a layer of protein that surrounds your genetic material. the genetic material in the HIV virus is:to. Double-stranded DNA (dsDNA)b. Single-stranded DNA…10. Protein expression can be blocked by antisense oligonucleotides. Which mechanism enables antisense oligonucleotides to block protein synthesis? O Antisense oligonucleotides bind to ribosomes and inhibit their function. Antisense oligonucleotides bind to DNA in the nucleus and inhibit the synthesis o MRNA. Antisense oligonucleotides bind to ribosomal RNA (rRNA) and inhibit ribosome assembly. Antisense oligonucleotides bind to messenger RNA (MRNA) and prevents mRNA binding to ribosomes.1. (a) RNA polymerase synthesis in a 5 -3 direction Gene is switched ON Gene is switched OFF Does NOT affect the gene expression (b) DNA synthesis in a 5 -3 direction Gene is switched ON Gene is switched OFF Does NOT affect the gene expression
- Gene expression includes which two of the following processes? O A. transcription and replication O B. replication and repression O c. protein synthesis and replication O D. mutation and cell division O E. transcription and translation1. Point mutations are changes to a single base/nucleotide in the DNA sequence of a gene. This sequence change can alter the protein made from the gene in different ways depending on the type of mutation (missense, nonsense, synonymous/silent, frameshift, and loss of stop). Below is an mRNA sequence and its translated protein. For each question, select a single base/nucleotide in the result in the indicated mutation (note: more than one answer may be corre table one) Normal Sequence: mRNA: 5' protein: GCACGU-AUG-UAC-GGG-CAU-ACA-UGA-UCGGACC 3' Met Tyr Gly His Thr Stop Nonsense Mutation: mRNA: 5' GCACGU- Protein: Silent/Synonymous Mutation: mRNA: 5' GCACGU- Protein: position U A 2nd position CA U Phe Ser Tyr Phe Ser Tyr Leu Ser stop Leu Ser stop Leu Pro His Leu Pro Leu Leu Pro Pro His Gin Gin lle Thr Asn lle Thr Asn lle Thr Met Thr Val Ala G Val Ala Val Ala Val Ala Lys Lýs 3rd Gostion Cys Cys stop Trp Arg Arg Arg Arg Ser Ser Arg Arg Gly Gly Asp Asp Glu Gly Glu Gly Amino Acids DADADADAG U…What does this expression mean? DNA → RNA→ Protein A DNA first turns into RNA; then the RNA turns into a protein. B The information in a DNA molecule is used to make an RNA molecule; then the information in the RNA is used to build a protein. C A cell passes through a phase where it has only DNA, then only RNA, then only protein.
- Two cells use the same segment of DNA to produce two different proteins. The mRNA transcribed by cell A contains more introns than does the mRNA produced by cell B. Which of the following is true about the proteins of these cells? O A The protein for cell A is longer. O B. The protein for cell A is shorter. O C. Cell A produces more of this protein. O D. Cell A produces less of this protein. mswered MacBook Air F3 F4 F7 F9 @ # $ % & * 2 5 6 7 W E R S D H KHow does position effect influence gene expression? 1 | The movement of the genetic material on the chromosome by inversions or translocations may place a coding sequence near a new regulatory region, thus activating the expression of the gene. The movement of the gene may place it into a region that is highly condensed (heterochromatin). The movement of a gene may remove it from its normal promoter, thus silencing the gene. O All of the above answers are correctWhen a gene is expressed, it.. (Choose the answer the illustrates the definition of gene expression.) O is replicated so that there are two copies of the gene. is transcribed and translated. duplicated. O is mutated, then these mutations are corrected.
- I. The retinoic acid receptor (RAR) is a transcription factor that is similar to steroid hormone receptors. Thesubstance (ligand) that binds to this receptor is retinoicacid. One of the genes whose transcription is activatedby retinoic acid binding to the receptor is myoD. Thediagram that follows shows a schematic view of theRAR proteins produced by genes into which one oftwo different 12-base double-stranded oligonucleotides had been inserted in the ORF. The insertion site(a–m) associated with each mutant protein is indicatedwith the appropriate letter on the polypeptide map.For constructs encoding proteins a–e, oligonucleotide 1(5′ TTAATTAATTAA 3′ read off either strand) wasinserted into the RAR gene. For constructs encoding proteins f–m, oligonucleotide 2 (5′ CCGGCCGGCCGG 3′)was inserted into the gene.NH2 f g h i j k l m COOHa b c d eThe wild-type RAR protein can both bind DNA and activate transcription weakly in the absence of retinoic acid(RA) and strongly in RA’s presence. Each…Gene expression is... O How genes are replicated into two new strands identical to each other O How genes are duplicated, forming a new gene O How genes are mutated, creating a new allele O How genes are transcribed and translated into proteinWhich of the following statament is NOT TRUE about gene expression?a. The expression of genes that code for proteins includes two stages: replication and translationb. Translation is the synthesis of a polypeptide using the information in the mRNA.c. During gene expression, the information encoded in genes is used to make specific polypeptide chains or RNA molecules.d. Gene expression is the process by which DNA directs the synthesis of proteins