Treatment of Sleeping 1 Disorders Should Be Considered in 2 Clinical Management of Parkinson’s Disease 3 4 5 Altair B. dos Santos1, George E. Barreto, PhD2, Kristi A. Kohlmeier, PhD3 * 6 7 1Department of Biological Sciences, Universidade Estadual do Sudoeste da Bahia, 8 Brazil. 9 2Departmento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad 10 Javeriana, Bogotá D.C., Colombia. 11 3Faculty of Health and Medical Sciences, Department of Drug Design and 12 Pharmacology, University of Copenhagen, Denmark. 13 14 15 Following two decades of research after the first clinical reports that sleep disturbances 16 can precede signs and motor symptoms of Parkinson 's disease (PD), studies performed 17 examining sleep at the …show more content…
Nor is it standard practice to suggest 31 prophylactic approaches in these patients to curb onset of PD. Clinical acceptance of 32 the link between sleeping disorders and later life onset of PD could be gained from 33 longitudinal studies with human patients focused on elucidating whether there exists a 34 strong association and/or causality between sleeping disorders and PD. However, this 35 approach raises ethical issues, especially if, in an attempt to provide compelling 36 evidence for causality, preventative interventions are given to one group of subjects and 37 not another. Nevertheless, at this time, improved monitoring and documentation of the 38 neurological progress of patients with sleeping disorders should be combined with 39 imaging studies in order to better characterize changes in neural regions controlling 40 sleep which occur in patients eventually presenting with PD. Animal models of PD, 41 which have contributed to provided compelling evidence that there is a link between 42 sleep and PD, should continue to be exploited to provide further
Commonly known as Delayed Sleep Phase Disorder (DSPD) and other names, is a disorder in which the persons internal body clock is not in sync with the morning-rise evening-sleep pattern of the majority of people. Individuals with this disorder are not able to sleep and wake at the times that are regulated by normal work and school hours. They usually get enough sleep to keep them at a functional level through the day but not enough to be considered “well rested”. Polysomnography and actigraphy are tests commonly ordered for some sleep disorders to determine the illness. The cause of Delayed Sleep Phase can include a variety of reasons; puberty being one of the main causes, but some people are born with the disorder. The short term and long term effects of this illness is unfortunate for a person’s overall health. Overall cures to this disorder have not been found yet. Doctors have suggested sleeping pills to help or other alternatives. The disorder affects the timing of sleep, peak period of alertness, the core body temperature rhythm, hormonal and other daily cycles.
Sleep is a vital component to sustaining life in humans. Even though everyone participates in sleeping, many individuals do not understand the true significance of sleeping, and what benefits and consequences come with too much or too little sleep. Sleep comes in different stages throughout the period of rest, with some stages being more important than others. By interrupting various stages, different types of problems can arise from which stage is being affected. In particular, elder adults are affected in larger numbers to a more extensive depth of issues. “However, aging does not mean elders should encounter sleep disorders; it merely increases the possibility that more elders will seek help to manage the problem” (Song, Hollenbeck, Blair, Schatzkin, Chen. 2012. p.316) By understanding possible causes for sleep disorders, what kinds of physiological effects this has on the aged anatomy, and the types of problems that appear in the psychological aspect, it becomes achievable to begin working towards reversing complications and promoting elder sleep health.
Parkinson's is a disease that may happen in younger people, but the risk mainly increases
Ramig and colleagues (2001) performed a study to examine the long-term effects of using Lee Silverman Voice Treatment (LSVT) to improve vocal function in individuals with Parkinson’s Disease (PD). Ramig and colleagues (2001) compared LSVT to received respiratory therapy (RET) to control for extraneous variables. Subjects were recruited from a variety of sources which helped to reduce recruitment bias (Ramig et al., 2001). Individuals with any laryngeal pathology unrelated to PD were excluded from the study (Ramig et al., 2001). All 33 subjects were stratified based on: age, time post-diagnosis, stage of disease, score on the unified Parkinson’s disease rating scale, and clinical ratings on speech and voice severity (Ramig et al., 2001). Subjects were then randomly divided into 2 groups and received either LSVT or RET provided in four one-hour weekly sessions for four weeks (Ramig et al., 2001).
Parkinson's disease is a progressive degenerative disorder of the central nervous system that affects the motor system. It is marked by tremor at rest, muscular rigidity, postural instability, and slow, imprecise movement. The most obvious symptoms are movement related, which include; shaking, rigidity, slowness of movement, difficult with walking, balance, and gait. Other motor symptoms include: posture disturbances, such as a decrease in arm swing, a forward flexed posture, and the use of small steps when walking. Speech and swallowing disturbances are also common motor problems that can appear as well to a patient with Parkinson's disease. Young adults rarely experience Parkinson's disease because it is more common to affect
For many 50 year olds, tasks such as writing or walking can be easily preformed without much attention. In fact, the term “task” seems to stress that there is a greater level of effort than is truly exerted in order for the average person to perform these actions. However, for a patient of Parkinson’s Disease who is diagnosed on average at the age of 50, these every day activities take a great deal of time, attention, and effort to be preformed (Huston). With the growth of research about this disease, a variety of treatment options ranging from medication to surgery are currently available to patients who suffer from the debilitating effects of Parkinson’s Disease.
* Memories: Brain stores short-term memories of the experience in a part of the brain called the hippocampus, then those memories are later “consolidated” and transferred to another part of the brain, more precisely in neocortex, for a long-term storage;
Parkinson’s disease is a disease that affects the way a person moves. Movement for a parkinson’s sufferer can be slow and shaky. There are different types of parkinson’s, multiple system atrophy (MSA), progressive supranuclear palsy (PSP),normal pressure hydrocephalus and tremors including essential tremors, dystonic tremors, indeterminate tremors and atypical tremors. These tremors are all part of this disease and affect all patients in different ways.
In the prospect of this article, sleep disorder can play a major role in your life. When there becomes a lack of sleep, there are many things that could occur to your body. There could be a risk of cardiovascular disease, diabetes, infections, or Alzheimer’s disease. For example a man by the name of Michael Arnott had trouble sleeping in his fifty’s, but he didn't know the reason behind this. His wife, Mary White stated, “All of a sudden there'd be a change in the speed and I'd look over, and his eyes would be starting to close,” she remembers (White). Now, Arnold was in denial when it came to his problems of sleeping because he thought that he was in good condition. After getting an analysis from the doctor saying that he has moderate obstructive
New discoveries on the treatment of Parkinson’s disease show that dopamine neurons can treat Parkinson’s disease. Parkinson’s disease is a disorder of the nervous system, which is a progressive disease. Parkinson’s disease is marked by tremors, muscular stiffness. It mainly affects people who are either elderly or middle aged. Although Parkinson’s disease cannot be cure lab grown dopamine can assist in being able to manage the disease in an enhanced way. Although Parkinson’s disease is not curable but can be treatable it still needs more work in order to make a cure in the future. Dopamine helps regulate movement and when there is a deficiency in dopamine that results in Parkinson’s disease.
Question 1: A person with Parkinson’s disease (PD) demonstrates physical, cognitive and behavioural difficulties. These difficulties are based on the evidence of years of research about PD and the characteristics that are associated with this neurodegenerative disorder. Jankovic (2008) describes cardinal features of PD; tremor at rest, rigidity, bradykinesia, and postural instability which will be discussed in terms of their key aspects. Tremor tends to not interfere with daily activities as the tremor decreases with voluntary movement (Dauer, & Przedbors, 2003). Rest tremor disappear with action or during sleep, and usually involve the hands and may involve the lips, chin, jaw and legs; however, rarely involve the neck, head or voice (Jankovic,
There have been times during my life when my motivation has blossomed from different emotions. The day after Mother’s 65th birthday, love and fear intertwined into a knot inseparably made from a single thread. For on that day, Mother received the diagnosis of having Parkinson’s disease, at the time I did not comprehend the gravity of what that diagnosis actually meant. My desire to learn more about Parkinson’s disease initially stemmed from fear of what my mother would endure as the disease progressed, and love, motivated my desire to improve the quality of her life by any measure possible. Fortunately, the knowledge I gained aided my family in understanding and caring for Mother with great compassion. Sadly, over the following years, this
sleep disorders such as insomnia, obstructive sleep apnea (OSA), excessive daytime sleepiness (EDS) and fatigue, sleep deprivation and restless leg syndrome (RLS) are increasingly seen in clinical practice. Sleep is considered vital for the preservation of daytime cognitive function and physiological well-being. The insufficient sleep can have detrimental effects on work-life balance, health and global security. The economic burden resulting both at individual and social levels is important. Moreover, sleep disturbances are often associated with other major medical problems such as chronic pain, cardiovascular disease, mental illness, dementia, gastrointestinal disorders and diabetes mellitus. So in order to properly care for patients with
One man, one brain and one hundred trillion synapse. It takes a moment for one to experience damage to ones brain and neurons within the brain and a lifelong journey of recovery. The brain consists of many neurons which are single nerves. This essay intends to discuss whether there is effective recovery from brain damage by describing the intricate process of neural networks in the brain. It will include the fascinating and continuously evolving process of neuroplasticity. It will elaborate on the other therapies that coincide with neuroplasticity within the recovery process. Lastly, the evidence which stands as verification of the theory providing a better understanding for one.
Parkinson’s disease is one of the most frightening and deadliest diseases of them all, and is potentially life altering not only for the individual who gets it, but for their loved ones as well. Commonly found amongst the elderly,” Parkinson’s disease (PD) is a progressive, neurological disease that mainly affects movement but can also affect cognition.” (What is Parkison’s Disease), and it effects people who are on average ages 60 years and older. As we as humans age and progress through life, so does our bodies. Change within the body can be potentially be for the good, change that is not necessarily good. In this case, Parkinson’s disease is a progressive and neurological disease that effects move and cognition of the body. As stated in the text, “Parkinson’s disease results from the destruction of nerve cells in a part of the brain called the basal ganglia” (What is Parkison’s Disease). In other words, Parkinson’s disease effects and ruptures nerve cells in a major part of the brain, which in essence causes negative effects and memory/brain function. Several parts of the brain work simultaneously together to send signals to each other to coordinate all of our thoughts, movements, emotions, and senses. When we have the urge to move, a signal is sent from a part of the brain named the basal ganglia to another part of the brain named the thalamus, which is then sent to the cerebral cortex. This is a disease that effects many elderly people worldwide, and the families of