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Chronic Obstructive Pulmonary Disease ( Copd )

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Chronic Obstructive Pulmonary Disease (COPD) is progressively common amongst patients within the United States. The disease is more common in patients with a long smoking history. Inflammatory changes are largely responsible for the development and symptoms of COPD. COPD is typically managed according to classification of severity based on the GOLD guidelines. Anoro Ellipta is a new once daily FDA approved drug. It is a combination of a long-acting muscarinic antagonist (LAMA) and a long-acting b2-agonist that should be considered in the management of COPD. Efficacy studies have proved Anoro Eliipta in preventing COPD exacerbations and show it is well tolerated amongst patients.
Learning Objectives
• Define COPD and identify risk factors …show more content…

Pharmacological management includes the use of bronchodilators. The latest bronchodilator Anoro Ellipta seeks to manage COPD while simultaneously improving patient compliance. To understand the role of pharmacological treatment it is important to understand the fundamentals of COPD.
What is COPD?
Chronic Obstructive Pulmonary Disease (COPD) is an ailment defined by irreversible airway limitation. COPD is an umbrella term covering emphysema, in which there is destruction and enlargement of the lung alveoli, chronic bronchitis, characterized by chronic cough and phlegm production, and small airways disease, a condition in which airways are narrowed.2 Cigarette smoking is responsible for most cases of COPD and is responsible for 90% of the risk for developing COPD.3 Patients who do not smoke can also develop COPD via recurrent infections, exposure to fumes or pollution, and second hand smoking.2 Genetic factors have been found to increase the risk of developing COPD, most notably Alpha1-antitrypsin deficiency, which is present in 1to 2% of COPD patients.2 COPD currently affects more than 10 million Americans and holds a spot as the fourth leading cause of death.2 The National Health Interview Survey reports the

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