Chronic Obstructive Pulmonary Disease: Nebulized Furosemide

The study included 100 patients with COPD. All patients fulfilled the inclusion and exclusion criteria. According to its demographic and clinical parameters and treatment groups differ among themselves. Completed the study, all patients included in the study. The therapy in all patients with a clinically meaningful improvement of symptoms was observed.

A. has a history of smoking for 50 years and being diagnosed with COPD 2 years ago. Development of COPD and its exacerbations may be a leading caused by bacteria, viruses, or environmental pollutants, including cigarette smoke. Coussa, et al, “Expiratory flow limitation (EFL), as a consequence of airway inflammation is the pathophysiological hallmark of COPD.” Exacerbations fundamentally reflect acute worsening of EFL and there is evidence for both increased airway inflammatory activity and worsening airway obstruction as likely explanations.

COPD is the third leading cause of death in the United States and a major cause of morbidity, including visits to a physician, emergency department, or urgent care, as well asand hospitalizations1,2

With all the knowledge, we have on COPD there is still so much to learn and improve on. This disease is not one we can dissolve out of existence like polio and the bubonic plague. Even though it may seem endless we have to continue work to reduce those affected and the effects of this disease. This disease is life threatening and a horrendous disease to live with so all efforts on improvement are greatly appreciated by patients affected by it and professionals who are trying to improve life for these

Chronic obstructive pulmonary disease (COPD) is preventable disease that has a detrimental effects on both the airway and lung parenchyma (Nazir & Erbland, 2009). COPD categorises emphysema and chronic bronchitis, both of which are characterised by a reduced maximum expiratory flow and slow but forced emptying of the lungs (Jeffery 1998). The disease has the one of the highest number of fatalities in the developed world due to the ever increasing amount of tobacco smokers and is associated with significant morbidity and mortality (Marx, Hockberger & Walls, 2014). Signs and symptoms that indicate the presence of the disease include a productive cough, wheezing, dyspnoea and predisposing risk factors (Edelman et al., 1992).

Millions of individuals suffer and die from Chronic Obstructive Pulmonary Disease (COPD) each year in our nation. Currently, there is no cure for COPD; therefore, the most beneficial goal for these patients is to provide enhanced quality of life that includes limited admissions to the hospital setting and decreased exacerbations. Management of this disease process through proper patient education and multidisciplinary collaboration improves a COPD patient’s ability to maintain a healthier state of life as well as decrease their chance of a costly hospital readmission (Chamberlain, Lau, Siracuse, 2017).

Beta2 agonists act directly on bronchial smooth muscle to cause bronchodilation. They are the most widely used bronchodilators for COPD. Short-acting beta2 agonists are the most commonly used short-acting bronchodilators in COPD.

As of not long ago, the significant objective of COPD treatment was the diminishment of side effects. Nonetheless, with the acknowledgment that intensifications of COPD are extremely normal, have a noteworthy antagonistic effect on personal satisfaction, and may speed sickness movement, rules and clinical consideration are concentrating on decreasing future dangers, for example, the counteractive action and treatment of intensifications (2013, August 23). In created nations the hospitalization of COPD patients, brought on transcendently by intensifications, represents over half of direct human services

As you already know, Chronic Obstructive Pulmonary Disease (COPD), manifests itself when the passageway of air to the lungs is severely obstructed, thus preventing sufficient flow of oxygen into the bloodstream.1 The pathophysiology of COPD is a complex process that is the result of multiple airway diseases that simultaneously contribute to the impairment of airflow in the lungs.1 Specifically, the overlapping outcome of chronic bronchitis and emphysema is the pathogenesis of COPD.1 The risk factor for the COPD is influenced by the individual’s genetics, age, gender, exposure to air pollution, socioeconomic status, and the use of tobacco products.1 The use of tobacco products can increase the development of COPD.1 However, individuals that don’t smoke can also attain COPD.1 Therefore, COPD is not exclusive to individuals that smoke on a daily basis.1 In fact, genetics and the natural aging process plays a part in the development of pulmonary issues.1 For example, it has been proven that a deficiency in the alpha -1 antitrypsin gene is correlated with the development of COPD.1 The natural deterioration of lung tissue, coupled with the long term exposure to environmental elements, explains why the risk of attaining COPD increases as one progresses to the latter stages of their lives.1 In a healthy individual, goblet cells secrete about one liter of mucous that provides a moist surface over the lungs, trachea, and esophagus.1 The cilia on the pseuodocolumnar epithelial cells continuously sweep the mucus in the lungs in an upward motion.1 The cilia sweeps the mucosal trapped debris up, and removes pathogens and other foreign particles out the pulmonary tissue.1 In individuals with COPD, the pathogenesis of the disease creates structural modifications of the lung tissue, which result in deformed and nonfunctioning cilia.2 The lack of functioning cilia leads to the buildup of mucous, pathogens, and subsequent respiratory infections.2 Furthermore, the body tries to combat

COPD, however, is an adult disease whose leading cause is long-term cigarette smoking. Airway inflammation with lymphocytes, neutrophils, and macrophages is common in COPD (2), and remodeling of airways commonly occurs. While airway obstruction in asthma is usually reversible, there can be a fixed obstructive component, and in COPD, where there is usually a significant fixed obstructive component, there can be partial reversibility in airway obstruction (2). There are patients who present with an overlap syndrome with mixed features of COPD/asthma (2). COPD is also potentially preventable, if one avoids cigarette smoking, which often times is the primary cause. The most common recognized forms of COPD are chronic bronchitis, seen as bouts of coughing and severe

Progressive, persistent airflow limitation and chronic airway inflammation are both characteristics of chronic obstructive pulmonary disease (COPD). A combination of diffuse small airway disease and destruction of lung parenchyma, also known as emphysema, are the results that cause persistent airflow limitation. Spirometry is used most often to diagnose. The ratios that are checked are forced vital capacity and forced expiratory volume in one second. COPD is diagnosed in stages ranging from mild to very severe. The diagnosis is also based on age and sex of the patient. Age is a factor because due to the fact that as we age the FEV1/FVC declines. (European Lung White Book Chapter 13)

COPD, or Chronic Obstructive Pulmonary Disease, is one of the most common lung diseases. Thousands of people are diagnosed every year, and it recently moved up to the 3rd leading cause of death in the U.S., behind heart disease and cancer. This paper will discuss disease pathology, the most common and recently discovered diagnostic tests, as well as treatment options. It will also address end of life care.

According to the Centers for Disease Control and Prevention (CDC), COPD is the fourth leading cause of death in the United States. Approximately 12 million people in the United States have been diagnosed with COPD. Many more may be affected and don’t know they have it. Its generality increases with age. Men are more likely to have the disease, but the death rate for men and women is the same (2014).

Chronic Obstructive Pulmonary Disease, also known as COPD, is the third leading cause of death in the United States. COPD includes extensive lungs diseases such as emphysema, non-reversible asthma, specific forms of bronchiectasis, and chronic bronchitis. This disease restricts the flow of air in and out of the lungs. Ways in which these limitations may occur include the loss of elasticity in the air sacs and throughout the airways, the destruction of the walls between air sacs, the inflammation or thickening of airway walls, or the overproduction of mucus in airways which can lead to blockage. Throughout this paper I am going to explain the main causes, symptoms, diagnosis, and ways to reduce COPD.

S. It is the fourth leading cause of chronic morbidity and mortality in the United States and is projected to rank fifth in 2020 as a worldwide burden of disease according to a study published by the World Bank/World Health Organization (Pauwels, 2012). Yet; COPD fails to receive adequate attention from the health care community and government officials (Pauwels, 2012). In 1998, in an effort to bring more attention to COPD, its management, and its prevention, a committed group of scientist encouraged the U.S. National Heart, Lung, and Blood Institute and the World Health Organization to form the Global Initiative for Chronic Obstructive Lung Disease (GOLD) (Pauwels, 2012). GOLD’s intention is to bring awareness to individuals who treat COPD and the individuals who suffer and die every year due to the complications from the disease. GOLD used a consensus report for this study and updates the version to reflect on vital changes, stages and signs of COPD. The goals for GOLD are to improve management; and prevention of COPD through effort of people involved in all areas of healthcare and the policies of health care, including worldwide involvement. One strategy to help achieve the objectives of GOLD is to provide health care to workers, health care authorities, and the general public with state-of-the-art information about COPD and specific recommendations on the most appropriate management and prevention strategies (Pauwels,