Probability and Statistics for Engineering and the Sciences
Probability and Statistics for Engineering and the Sciences
9th Edition
ISBN: 9781305251809
Author: Jay L. Devore
Publisher: Cengage Learning
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Chapter 6.1, Problem 6E

Urinary angiotensinogen (AGT) level is one quantitative indicator of kidney function. The article “Urinary Angiotensinogen as a Potential Biomarker of Chronic Kidney Diseases” (J. of the Amer. Society of Hypertension, 2008: 349-354) describes a study in which urinary AGT level (μg) was determined for a sample of adults with chronic kidney disease. Here is representative data (consistent with summary quantities and descriptions in the cited article):

Chapter 6.1, Problem 6E, Urinary angiotensinogen (AGT) level is one quantitative indicator of kidney function. The article

An appropriate probability plot supports the use of the lognormal distribution (see Section 4.5) as a reasonable model for urinary AGT level (this is what the investigators did).

  1. a. Estimate the parameters of the distribution. [Hint. Remember that X has a lognormal distribution with parameters μ and σ2 if ln(X) is normally distributed with mean μ and variance σ2.]
  2. b. Use the estimates of part (a) to calculate an estimate of the expected value of AGT level. [Hint: What is E(X)?]
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Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 90th percentile for their age, gender, and height) and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period. To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after 4 years of follow-up. The data are given in Table 1 . Table 1 Pilot data on left ventricular mass (LVM) in children from the Bogalusa Heart Study ID Baseline LVM (g) 4- year LVM (g) Change (g)* 1 139 163 24 2 134 126 -8 3 86 142 56…
Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 90th percentile for their age, gender, and height) and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period. To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after 4 years of follow-up. The data are given in Table 1 . Table 1 Pilot data on left ventricular mass (LVM) in children from the Bogalusa Heart Study ID Baseline LVM (g) 4- year LVM (g) Change (g)* 1 139 163 24 2 134 126 -8 3 86 142 56…
Left ventricular mass (LVM) is an important risk factor for subsequent cardiovascular disease. A study is proposed to assess the relationship between childhood blood-pressure levels and LVM in children as determined from echocardiograms. The goal is to stratify children into a normal bp group (< 90th percentile for their age, gender, and height) and an elevated bp group (≥ 90th percentile for their age, gender, and height) and compare change in LVM between the two groups. Before this can be done, one needs to demonstrate that LVM actually changes in children over a 4-year period. To help plan the main study, a pilot study is conducted where echocardiograms are obtained from 10 random children from the Bogalusa Heart Study at baseline and after 4 years of follow-up. The data are given in Table 1 . Table 1 Pilot data on left ventricular mass (LVM) in children from the Bogalusa Heart Study ID Baseline LVM (g) 4- year LVM (g) Change (g)* 1 139 163 24 2 134 126 -8 3 86 142 56…

Chapter 6 Solutions

Probability and Statistics for Engineering and the Sciences

Ch. 6.1 - Of n1 randomly selected male smokers, X1 smoked...Ch. 6.1 - Suppose a certain type of fertilizer has an...Ch. 6.1 - Consider a random sample X1,..., Xn from the pdf...Ch. 6.1 - A sample of n captured Pandemonium jet fighters...Ch. 6.1 - Let X1, X2,..., Xn represent a random sample from...Ch. 6.1 - Suppose the true average growth of one type of...Ch. 6.1 - In Chapter 3, we defined a negative binomial rv as...Ch. 6.1 - Let X1, X2,..., Xn be a random sample from a pdf...Ch. 6.1 - An investigator wishes to estimate the proportion...Ch. 6.2 - A diagnostic test for a certain disease is applied...Ch. 6.2 - Let X have a Weibull distribution with parameters ...Ch. 6.2 - Let X denote the proportion of allotted time that...Ch. 6.2 - Let X represent the error in making a measurement...Ch. 6.2 - A vehicle with a particular defect in its emission...Ch. 6.2 - The shear strength of each of ten test spot welds...Ch. 6.2 - Consider randomly selecting n segments of pipe and...Ch. 6.2 - Let X1,..., Xn be a random sample from a gamma...Ch. 6.2 - Prob. 28ECh. 6.2 - Consider a random sample X1, X2,, Xn from the...Ch. 6.2 - At time t = 0, 20 identical components are tested....Ch. 6 - An estimator is said to be consistent if for any ...Ch. 6 - a. Let X1,.., Xn be a random sample from a uniform...Ch. 6 - At time t = 0, there is one individual alive in a...Ch. 6 - The mean squared error of an estimator is MSE ()...Ch. 6 - Prob. 35SECh. 6 - When the population distribution is normal, the...Ch. 6 - When the sample standard deviation S is based on a...Ch. 6 - Each of n specimens is to be weighed twice on the...
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