Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 6, Problem 5TYU
Summary Introduction
Concept introduction: Receptors are large protein or glycoproteins that bind with the signaling molecule (ligand). The cells undergo receptor-ligand alterations and initiate the biological response. The ligand molecule binds with the cell surface receptors. G-protein-linked receptor may be monomeric or oligomeric. It belongs to a family of transmembrane proteins that loop back and forth through the plasma membrane for seven times.
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G protein–linked receptors (a) inactivate G proteins (b) activate first messengers (c) consist of 18 transmembrane alpha helices (d) have a tail that extends into the cytosol with a binding site for a G protein (e) are located in the cytoplasm or nucleus
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Chapter 6 Solutions
Biology (MindTap Course List)
Ch. 6.1 - Describe the four main processes essential for...Ch. 6.1 - What is the sequence of events that takes place in...Ch. 6.1 - Prob. 2CCh. 6.2 - Compare three types of signaling molecules:...Ch. 6.2 - Prob. 1CCh. 6.2 - Prob. 2CCh. 6.2 - Prob. 3CCh. 6.3 - Identify mechanisms that make reception a highly...Ch. 6.3 - Prob. 4LOCh. 6.3 - Prob. 1C
Ch. 6.3 - Prob. 2CCh. 6.3 - Prob. 3CCh. 6.3 - Prob. 4CCh. 6.4 - Prob. 5LOCh. 6.4 - Trace the sequence of events in signal...Ch. 6.4 - How is an extracellular signal converted to an...Ch. 6.4 - Prob. 2CCh. 6.4 - Prob. 3CCh. 6.5 - Prob. 7LOCh. 6.5 - Prob. 8LOCh. 6.5 - Prob. 1CCh. 6.5 - Prob. 2CCh. 6.5 - Prob. 3CCh. 6.6 - Cite evidence supporting a long evolutionary...Ch. 6.6 - Prob. 1CCh. 6 - During signal transduction (a) the cell converts...Ch. 6 - When a signaling molecule binds with a receptor,...Ch. 6 - G proteinlinked receptors (a) inactivate G...Ch. 6 - Prob. 4TYUCh. 6 - Prob. 5TYUCh. 6 - Calcium ions (a) can act as second messengers (b)...Ch. 6 - When growth hormone binds to an enzyme-linked...Ch. 6 - Scaffold proteins (a) release kinases and...Ch. 6 - Prob. 9TYUCh. 6 - Prob. 10TYUCh. 6 - More than 500 genes have been identified in the...Ch. 6 - Prob. 12TYUCh. 6 - Prob. 13TYUCh. 6 - EVOLUTION LINK Cell signaling in plant and animal...Ch. 6 - EVOLUTION LINK Some of the same G proteinlinked...Ch. 6 - Prob. 16TYU
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- Scaffold proteins (a) release kinases and phosphatases into the extracellular fluid (b) bind G proteins to cell membranes (c) increase accuracy but slow signaling cascades (d) organize groups of intracellular signaling moleculesinto signaling complexes (e) are transcription factors found mainly in plant cellsarrow_forwardEach adenylyl cyclase molecule produces many cAMP molecules in an example of (a) receptor up-regulation (b) receptor down-regulation (c) signal amplification (d) scaffolding (e) similarities produced by evolutionarrow_forwardAn enzyme-linked receptor (a) is a cytoplasmic protein (b) would not be found on plant cell surfaces (c) forms a dimer with another enzyme-linked receptor when a ligand binds to it (d) is typically an adenylyl cyclase molecule(e) typically activates ion channelsarrow_forward
- Binding of a signaling molecule to which typeof receptor leads directly to a change in thedistribution of substances on opposite sides of themembrane?(A) intracellular receptor(B) G protein-coupled receptor(C) phosphorylated receptor tyrosine kinase dimer(D) ligand-gated ion channelarrow_forwardWhich receptor undergoes clustering and autophosphorylation in response to activation by a signal? Group of answer choices: a)Ligand-gated ion channels b)Receptor Tyrosine Kinases (RTKs) c)G-Protein Coupled Receptors (GPCRs) d)Nuclear Receptorsarrow_forwardChemical synaptic transmission can be viewed as a specialized form of Ca) Contact signaling b) Paracrine signaling c) Electrical synaptic transmission d) (a) and (b) are both correct; (c) is incorrect e) (a), (b) and (c) are all correctarrow_forward
- What is the mechanism by which voltage-gated channels open in response to voltage changes? Choose the best answer: (a) Voltage changes cause release of ligand (b) Voltage changes shift the receptor from the inactivated to active state (c) Charged residues in the channel lead to a conformation change (d) Voltage changes lead to increased force from ions attempting to pass through (e) Voltage changes increase ion channel expression I wish to select answer (c), but I am not sure it is the best answer compared with (b) and (d). Thus I wish to seek your expertise advice.arrow_forwardThe activation of receptor tyrosine kinases is characterized by(A) dimerization and phosphorylation.(B) dimerization and IP3 binding.(C) a phosphorylation cascade.(D) GTP hydrolysis.arrow_forwardAn extracellular signaling molecule binds to cell surface receptor. This cell surface receptor changes shape and activates a trimeric G-protein. What kind of receptor is this? a) Ion-channel coupled receptor b) Receptor Tyrosine Kinase c) G-Protein coupled receptor d) All of the other answers are correct e) Enzyme-coupled receptorarrow_forward
- Signaling molecules interact with cells through specific macromolecular receptors. For each of the four receptors identified below, list all characteristics, by number, which accurately describe that receptor. (a) An adrenergic receptor (b) A steroid receptor (c) The LDL receptor (d) The insulin receptor (1) Located at the cell surface (2) Associated with the protein clathrin (3) Ligand binding stimulates the activity of phospholipase C (4) A transmembrane protein (5) A DNA-binding protein (6) Located in the cell interior (7) Receptor–ligand complex moves to the lysosome (8) Receptor–ligand complex becomes concentrated in the nucleus (9) Receptor activation can inhibit the synthesis of glycogen (10) The hormone–receptor complex activates specific gene transcription (11) Internalization decreases the synthesis of cholesterol esters (12) Action of this receptor diminishes the synthesis and activity of bhydroxy-b-methylglutaryl-CoA reductase (HMG-CoA reductase) (13) This receptor…arrow_forwardFat-soluble signaling molecules cross the cell membrane; but they affect only the target cells because: A) Only in target cells is the signaling molecule capable of initiating the phosphorylation chain that activates ion channels. B) only target cells have enzymes that break down the signaling molecule C) intracellular receptors are present only on target cells D) only targets have the appropriate DNA segmentsarrow_forwardWhat leads to the activation of protein kinase C?a) Release of intracellular Ca+2 + diacylglycerolb) Release of intracellular Mg+ + diacylglycerolc) Release of intracellular Ca+2 + glycerold) Release of intracellular Ca+2 + triacylglycerolarrow_forward
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license