Concept explainers
a)
Interpretation:
The conformation of either geranyl diphosphate or farnesyl diphosphate which shows likeness to guaiol is to be drawn.
Concept introduction:
Monoterpenes containing 10 carbon atoms are derived from geranyl diphosphate while sesqueterpenes containing 15 carbon atoms are derived from farnesyl diphosphate.
To give:
The conformation of either geranyl diphosphate or farnesyl diphosphate which shows likeness to guaiol.
b)
Interpretation:
The conformation of either geranyl diphosphate or farnesyl diphosphate which shows likeness to sabinene is to be drawn.
Concept introduction:
Monoterpenes containing 10 carbon atoms are derived from geranyl diphosphate while sesqueterpenes containing 15 carbon atoms are derived from farnesyl diphosphate.
To give:
The conformation of either geranyl diphosphate or farnesyl diphosphate which shows likeness to sabinene.
Want to see the full answer?
Check out a sample textbook solutionChapter 27 Solutions
Organic Chemistry
- Proline betaine is a putative osmoprotectant in plants and bacteria, helping to prevent dehydration of cells. Coo- CH, CH, Propose a plausible pathway for biosynthesis of this compound.arrow_forwardWhen 2-heptine was treated with aqueous sulfuric acid containing mercury(II) sulfate, two products were obtained, each with the molecular formula C7H14O, in approximately equal amounts. What are these two compounds. heptanal e 2-heptanona 2-heptanona e 3-heptanal 2-heptinona e 3-heptanal 2-heptanona e 3-heptanona ndarrow_forwardLook up the structure of lisdexamfetamine (Vyvanse), a drug used in the treatment of attention deficit hyperactivity disorder (ADHD). Redraw it and identify all the functional groups present. What is known about itstherapeutic properties?arrow_forward
- Tropone is an unusually basic carbonyl (C=O) compound. When it is treated with one equivalent of the strong acid HBF4, it forms A, C7H7OBF4. Draw the strucutre of A as its most stable resonance structure.arrow_forwardRing-A is considered a deoxy-pyranoside because it is missing an alcohol functional group on which carbon of ring-A? Use standard carbohydrate numbering. E в он он Oleandrin is a toxic cardiac glycoside found in the poisonous plant, oleander (Nerium oleander L). It has a very long IUPAC name: acetic acid [(35,5R, 10S,13R,14S,16S,17'R)-14-hydroxy-3-[[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyl- 2-tetrahydropyranyl]oxy]-10,13-dimethyl-17-(5-oxo-2H-furan-3-y)-1,2,3,4,5,6,7,8,9,11,12,15,16,17- tetradecahydrocyclopenta[a]phenanthren-16-yl] ester B.arrow_forwardBetamethasone is a synthetic anti-inammatory steroid used as a topical cream for itching. Betamethasone is derived from cortisol, with the following structural additions: a C=C between C1 and C2, a uorine at C9, and a methyl group at C16. The configuration at C9 is R, and the configuration at C16 is S. Draw the structure of betamethasone.arrow_forward
- Ch19-5: Which of the compounds is the intermediate called hemiacetal of the following reaction? 요 HO OH H₂SO (-H₂O) OH HO OH HO HOO O OH OHarrow_forwardProstaglandins are a class of eicosanoids, fatty acid derivatives involved in a variety of important phenomena, including fever, inflammation, and pain. The first step in prostaglandin synthesis involves the conversion of the 20-carbon fatty acid arachidonic acid to PGG2 by the enzyme prostaglandin endoperoxide synthase, or cyclooxy: Ibuprofen is one of several inhibitors of cyclooxogenase used therapeutically. Arachidonic acid 20₂ 0.5 1.0 1.5 2.5 3.5 cyclooxrygenase PGG₂ JOH محمد The following kinetic data were obtained for the enzyme cyclooxygenase in the absence of any inhibitor (1), and in the presence of ibuprofen (2) at a concentration of 48 [arachidonic acid] (uM) (1) v(uM/min) (2) v(uM/min) 23.5 32.2 36.9 41.8 44.0 16.67 25.25 30.49 37.04 38.91 Ibuprofen A. Plot the data in standard Michaelis-Menten form as well as in double-reciprocal form. B. Determine Vmax and Km for the enzyme. C. Based on this limited data set, what type of inhibition does ibuprofen likely exhibit?…arrow_forwardFollowing is a retrosynthesis for the coronary vasodilator ganglefene. (a) Propose a synthesis for ganglefene from 4-hydroxybenzoic acid and 3-methyl-3-buten-2-one. (b) Is ganglefene chiral? If so, which of the possible stereoisomers are formed in this synthesis?arrow_forward
- With the starting material provided, propose a synthesis pathway to prepare the diketone shown below. سلامarrow_forwardIndicate whether the compounds below undergo racemization when treated with aqueous acid or base. Foo H3C CH₂CH₂CH3 H CH3 O yes O yes O no CH3 O no O yes On noarrow_forward5. Ertugliflozin is a medication for the treatment of type 2 diabetes. OH HO 5.2 HO- OH Cl 5.1 Look at the structure and identify one of the following groups hemiacetal/acetal/hemiketal/ketal. Circle and label it. Based on your identification above, predict the stability of Ertugliflozin under aqueous acidic and basic conditions. Complete the sentence: Ertugliflozin is stable under aqueous acidic/basic unstable under aqueous conditions. acidic/basic conditions and 5.3 Support your predication by providing arrow-pushing mechanism for the hydrolysis reaction under the conditions you chose above. Use HA or B as needed. 5.4 Draw the structure of the hydrolysis reaction product(s).arrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage LearningChemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage Learning
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage Learning