Consider the following mRNA base sequence 5 ′ ACC CAC 3 ′ a. What dipeptide is coded for by this mRNA? b. What dipeptide is formed if a point mutation converts CAC to AAC? c. What dipeptide is formed if a point mutation converts ACC to ACU? d. What dipeptide is formed if a point mutation converts CAC to AAC and ACC to ACU?
Consider the following mRNA base sequence 5 ′ ACC CAC 3 ′ a. What dipeptide is coded for by this mRNA? b. What dipeptide is formed if a point mutation converts CAC to AAC? c. What dipeptide is formed if a point mutation converts ACC to ACU? d. What dipeptide is formed if a point mutation converts CAC to AAC and ACC to ACU?
b. What dipeptide is formed if a point mutation converts CAC to AAC?
c. What dipeptide is formed if a point mutation converts ACC to ACU?
d. What dipeptide is formed if a point mutation converts CAC to AAC and ACC to ACU?
(a)
Expert Solution
Interpretation Introduction
Interpretation: The dipeptide that is coded by the given mRNA has to be predicted.
Concept introduction: Ribonucleic acid (RNA) is responsible for the synthesis of the molecules that carry out essential cellular functions.. RNA contains the complementary base pairs. The four complementary bases of RNA are adenine, uracil, guanine and cytosine.
A compound possessing two amino acids joined together by one peptide bond is known as dipeptide. The amino acids present in the dipeptide are linked via peptide linkages.
Answer to Problem 22.136EP
The dipeptide that is coded by the given mRNA is Thr−His.
Explanation of Solution
The given mRNA base sequence is,
5'ACCCAC3'
The amino acid that specifies the base pair, ACC is threonine (Thr).
The amino acid that specifies the base pair, CAC is histamine (His).
Thus, the amino acid sequence or dipeptide for the given mRNA base sequence is Thr−His.
(b)
Expert Solution
Interpretation Introduction
Interpretation: The dipeptide that is formed if a point mutation converts CAC to AAC has to be predicted.
Concept introduction: Ribonucleic acid (RNA) is responsible for the synthesis of the molecules that carry out essential cellular functions.. RNA contains the complementary base pairs. The four complementary bases of RNA are adenine, uracil, guanine and cytosine.
The process of permanently changing the nucleotide sequence of a genome of any organism is known as mutation. In point mutation, one base is replaced by another base in the given base pair sequence.
Answer to Problem 22.136EP
The dipeptide that is formed if a point mutation converts CAC to AAC is Thr−Asn.
Explanation of Solution
The given mRNA base sequence is,
5'ACCCAC3'
If point mutation occurs in the given mRNA base sequence and converts CAC to AAC then the base sequence becomes,
5'ACCAAC3'
The amino acid that specifies the base pair, ACC is threonine (Thr).
The amino acid that specifies the base pair, AAC is asparagine (Asn).
Thus, the amino acid sequence or dipeptide formed after the point mutation is Thr−Asn.
(c)
Expert Solution
Interpretation Introduction
Interpretation: The dipeptide that is formed if a point mutation converts ACC to ACU has to be predicted.
Concept introduction: Ribonucleic acid (RNA) is responsible for the synthesis of the molecules that carry out essential cellular functions.. RNA contains the complementary base pairs. The four complementary bases of RNA are adenine, uracil, guanine and cytosine.
The process of permanently changing the nucleotide sequence of a genome of any organism is known as mutation. In point mutation, one base is replaced by another base in the given base pair sequence.
Answer to Problem 22.136EP
The dipeptide that is formed if a point mutation converts ACC to ACU is Thr−His.
Explanation of Solution
The given mRNA base sequence is,
5'ACCCAC3'
If point mutation occurs in the given mRNA base sequence and converts ACC to ACU then the base sequence becomes,
5'ACUCAC3'
The amino acid that specifies the base pair, ACU is threonine (Thr).
The amino acid that specifies the base pair, CAC is histamine (His).
Thus, the amino acid sequence or dipeptide formed after the point mutation is Thr−His because both ACC and ACU are coded by threonine only.
(d)
Expert Solution
Interpretation Introduction
Interpretation: The dipeptide that is formed if a point mutation converts CAC to AAC and ACC to ACU has to be predicted.
Concept introduction: Ribonucleic acid (RNA) is responsible for the synthesis of the molecules that carry out essential cellular functions.. RNA contains the complementary base pairs. The four complementary bases of RNA are adenine, uracil, guanine and cytosine.
The process of permanently changing the nucleotide sequence of a genome of any organism is known as mutation. In point mutation, one base is replaced by another base in the given base pair sequence.
Answer to Problem 22.136EP
The dipeptide that is formed if a point mutation converts CAC to AAC and ACC to ACU is Thr−Asn.
Explanation of Solution
The given mRNA base sequence is,
5'ACCCAC3'
If point mutation occurs in the given mRNA base sequence and converts CAC to AAC and ACC to ACU then the base sequence becomes,
5'ACUAAC3'
The amino acid that specifies the base pair, ACU is threonine (Thr).
The amino acid that specifies the base pair, AAC is asparagine (Asn).
Thus, the amino acid sequence or dipeptide formed after the point mutation is Thr−Asn because both ACC and ACU are coded by threonine only.
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