Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Textbook Question
Chapter 21, Problem 12PIAT
If researchers were attempting to stimulate the differentiation of IPS cells, which of the following would they most likely add to the cell-culture medium (liquid surrounding the cells)?
a. activin A, an extracellular signal protein
b. Sox-2, a transcription factor active in early development
c. Grb-2, an intracellular signal transduction protein
d. lactase, an enzyme that catalyzes the breakdown of lactose
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Which of the following statements did Yamanaka rely on to produce induced pluripotent stem cells (IPSC)? [Note: This is higher level thinking. All statements on their own are
correct and may be related to IPSC production but there is only one statement that played an essential role in the production of IPSC)
O A. A proportion of embryonic stem cells can differentiate into adult stem cells.
B. Only a small proportion of genes are expressed in each celI.
C. Telomerase is active in pluripotent stem cells.
D. All genes retain the potential to be expressed.
How does gene activation lead to cell differentiation? Explain the correct answer and explain why the others are wrong.
A. Different genes are activated in different cells, causing each cell to have a unique funcation
B. The same genes are actives in every cell of your body, causing every cell to function the same
C. Certain cells only have parts of DNA that causes cell deferentiation
D. Unique genes are in different cells, causing each cell to have a unique function
Cellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Please select a disease (like cancer) that can be modeled through the generation of induced pluripotent stem cells. You can use published literature and explain:1) why is it important to model such a disease?2) what were the key findings after modeling such a disease? 3) a drug that has been screened in this disease model. Explain in detail the main findings.
Chapter 21 Solutions
Biological Science (7th Edition)
Ch. 21 - 1. What is apoptosis?
a. an experimental technique...Ch. 21 - In adult animals, ______ are a source of...Ch. 21 - 3. What is a homeotic mutant?
a. an individual...Ch. 21 - 4. A tool-kit gene is _________.
Ch. 21 - What is the connection between genetic regulatory...Ch. 21 - Which of the following provides the strongest...Ch. 21 - QUANTITATIVE Imagine a situation in which a...Ch. 21 - 10. PROCESS OF SCIENCE Some stickleback fish...Ch. 21 - Will iPS cells be the cure for diabetes?
Type I...Ch. 21 - 12. If researchers were attempting to stimulate...
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Cell Differentiation | Genetics | Biology | FuseSchool; Author: FuseSchool - Global Education;https://www.youtube.com/watch?v=gwAz_BtVuLA;License: Standard YouTube License, CC-BY