General, Organic, and Biological Chemistry - 4th edition
General, Organic, and Biological Chemistry - 4th edition
4th Edition
ISBN: 9781259883989
Author: by Janice Smith
Publisher: McGraw-Hill Education
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Chapter 15.5, Problem 15.13P
Interpretation Introduction

(a)

Interpretation:

The chiral center in propranolol needs to be located.

Concept introduction:

A carbon center having all the different four substituents attached to it is known as a chiral center. If one of the four groups is the same, the carbon center will be achiral in nature.

Interpretation Introduction

(b)

Interpretation:

The enantiomers of propranolol molecule needs to be drawn.

Concept introduction:

If the molecules have the chiral center, the different forms of the molecules which are optically active are known as enantiomers of each other.

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(a) Locate the stereogenic centers in the ball-and-stick model of ezetimibe (trade name Zetia), a cholesterol-lowering drug. (b) Label each stereogenic center as R or S. ezetimibe
(a) assign R or S configuration to each chiral center, (b) Which compound are enantiomers? (c) Which compounds are diastereomers?
Draw both enantiomers of clopidogrel (trade name Plavix), a drug given to prevent the formation of blood clots in persons who have a history of stroke or coronary artery disease. Plavix is sold as a single enantiomer with the S configuration. Which enantiomer is Plavix?

Chapter 15 Solutions

General, Organic, and Biological Chemistry - 4th edition

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