Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 1, Problem 5CONQ
Summary Introduction

To review:

Whether the following examples are description of genetics at the molecular, cellular, organism or population level.

A. The HbS allele encodes a polypeptide that functions slightly differently from the polypeptide encoded by the HbA allele.

B. If an individual has two copies of the Hbs allele, that person’s red blood cells take on a sickle shape.

C. Individuals who have two copies of the HbA allele do not have sickle cell disease, but they are not resistant to malaria. People who have one HbA allele and one HbS allele do not have sickle cell disease and are resistant to malaria. People who have two copies of the HbS allele have sickle cell disease and this disease may significantly shorten their lives.

D. Individuals with sickle cell disease have anemia because their red blood cells are destroyed by the body.

Introduction:

The blood disease called sickle cell anemia is a heritable disease. The affected individuals do not have enough oxygen-carrying hemoglobin in their blood, which causes the red blood cells (RBCs) to shrink and acquire a sickle shape. This happens due to the defective β–globin gene.

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A human gene called the β-globin gene encodes a polypeptide that functions as a subunit of the protein known as hemoglobin. Hemoglobin carries oxygen within red blood cells. In human populations, the β-globin gene can be found as the more common allele called the HbA allele, but it can also be found as theHbS allele. Individuals who have two copies of the HbS allele have the disease called sickle cell disease. Are the followingexamples a description of genetics at the molecular, cellular, organism, or population level?A. The HbS allele encodes a polypeptide that functions slightly differently from the polypeptide encoded by the HbA allele.B. If an individual has two copies of the HbS allele, that person’s red blood cells take on a sickle shape. C. Individuals who have two copies of the HbA allele do not have sickle cell disease, but they are not resistant to malaria. People who have one HbA allele and one HbS allele do not have sickle cell disease, and they are resistant to malaria.…
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