Why would a deficiency in debranching enzyme be detrimental to glycogen metabolism? (Select all that apply) O Defects would prevent proper digestion of glycogen from the diet. O Glycogen stores in muscle and liver would not be fully degraded as alpha linkages would not be removed. Due to poor degradation, structural abnormalities in glycogen can impair tissue function in liver and muscle. O Defects in glycogen degradation impair its hormonal signaling ability.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter22: Gluconeogenesis, Glycogen Metabolism, And The Pentose Phosphate Pathway
Section: Chapter Questions
Problem 8P
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Why would a deficiency in debranching enzyme be detrimental to glycogen
metabolism? (Select all that apply)
O Defects would prevent proper digestion of glycogen from the diet.
Glycogen stores in muscle and liver would not be fully degraded as alpha 1->6
linkages would not be removed.
O Due to poor degradation, structural abnormalities in glycogen can impair normal
tissue function in liver and muscle.
O Defects in glycogen degradation impair its hormonal signaling ability.
Transcribed Image Text:Why would a deficiency in debranching enzyme be detrimental to glycogen metabolism? (Select all that apply) O Defects would prevent proper digestion of glycogen from the diet. Glycogen stores in muscle and liver would not be fully degraded as alpha 1->6 linkages would not be removed. O Due to poor degradation, structural abnormalities in glycogen can impair normal tissue function in liver and muscle. O Defects in glycogen degradation impair its hormonal signaling ability.
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