When the energetic needs of hepatocytes are being met, which of the following occurs? Acetyl-CoA inhibits pyruvate carboxylase. ATP inhibits fructose 1,6-bisphosphatase (FBPase1). ATPactivatesglycogenphosphorylase(phosphorylasea). Acetyl-CoA stimulates pyruvate kinase. None of the above Please answer asap and in short and content should not be palgarised please

When the energetic needs of hepatocytes are being met, which of the following occurs? Acetyl-CoA inhibits pyruvate carboxylase. ATP inhibits fructose 1,6-bisphosphatase (FBPase1). ATPactivatesglycogenphosphorylase(phosphorylasea). Acetyl-CoA stimulates pyruvate kinase. None of the above Please answer asap and in short and content should not be palgarised please

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...

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Elevated levels of acetyl-CoA will act as an effector for which of the following enzymes? more than one can be correct Pyruvate carboxylase. Pyruvate kinase Pyruvate dehydrogenase. Citrate synthase a-Ketoglutarate dehydrogenase.
Which of the following enzymes are activated after epinephrine/ glucagon bind to their receptors? (select all that apply) Glycogen phosphorylase kinase Acetyl CoA Carboxylase Lipase Glycogen phosphorylase Glycogen Synthase Protein Kinase A
Indicate whether each of the following statements is true or false. If false, correct the statement or provide a brief explanation for why it is false. Malonyl-CoA inhibits carnitine acyltransferase II , thus slowing transport of fatty acyl-CoA into mitochondrial matrix.
:Acetyl CoA produced from pyruvate occurs in the cytosol. not depends on the coenzyme biotin. is activated when pyruvate dehydrogenase (PDH, E1) of the pyruvate dehydrogenase complex is phosphorylated by PDH kinase in the presence of ATP. involves the participation of lipoic acid. all of the above is reversible.
Which of the following is TRUE? O Both AMP and ADP are negative regulators of glycogenolysis. ATP shifts the curve of glycogen phosphorylase to the left. O Citrate binds covalently to acetyl CoA carboxylase. Phosphofructokinase-1 is an allosterically regulated enzyme in glycolysis. The carnitine shuttle is positively regulated by Malonyl CoA.
What is caused (indirectly) by the binding of a glucagon molecule to its receptor on the surface of a liver cell? Phosphorylation of glycogen phosphatase, which results in it becoming less active. Dephosphorylation of glycogen synthase, which results in it becoming less active Phosphorylation of glycogen phosphorylase, which results in it becoming more active Dephosphorylation of phosphorylase kinase, which results in it becoming more active. Phosphorylation of glycogen synthase, which results in it becoming more active
When the acetyl-CoA produced during ß-oxidation in the liver exceeds the capacity of the citric acid cycle, the excess acetyl-CoA forms ketone bodies acetone, acetoacetate, and D-b-hydroxybutyrate. This occurs in severe, uncontrolled diabetes: because the tissues cannot use glucose, they oxidize large amounts of fatty acids instead. Although acetyl-CoA is not toxic, the mitochondrion must divert the acetyl-CoA to ketone bodies. What problem would arise if acetyl-CoA were not converted to ketone bodies? How does the diversion to ketone bodies solve the problem?
Below are some statements about the TCA Cycle. Which statement is true based on what we have learned in the class? Question 16 options: Oxaloacetate can be replenished from pyruvate carboxylation catalyzed by pyruvate carboxylase. The catabolism of proteins can only feed into the TCA cycle at one point, which is Acetyl-CoA. Acetyl-CoA has transporter proteins and can be transported directly from matrix to cytoplasm (for fatty acid synthesis). In TCA cycle, both Acetyl-CoA and Succinyl-CoA hydrolysis reactions are coupled with ATP/GTP synthesis.
All of the following enzymes catalyze a committed step EXCEPT: HMG-CoA reductase Fatty acyl-CoA synthetase Acetyl-CoA carboxylase I Pyruvate dehydrogenase complex All of the above enzymes catalyze a committed step The brain can directly use all of the following chemicals as energy source EXCEPT: Acetoacetate b-hydroxybutyrate Glucose Fatty acids All of the above can directly be used by the brain as energy source
If the brain needs glucose, then gluconeogenesis stops after reaction (9, 8, 10, 2) because (phosphoenolpyruvate, glucose, glucose-6-phosphaet, fructose-6-phosphate) can be exported from the hepatocyte using a transporter.
Which enzyme is used for both the synthesis and breakdown of acetoacetate? thiolase O HMG-CoA synthase OB-hydroxybutyrate dehydrogenase O B-Ketoacyl-CoA transferase
Which of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinase