When high levels of unfolded proteins are detected in the endoplasmic reticulum (ER), a eukaryotic cell responds by increasing the gene expression of chaperone proteins, which help proteins to fold correctly. BiP is a chaperone protein. You detect amounts of BiP MRNA and protein in the absence and presence of unfolded protein in the ER of a eukaryotic cell as shown in the figure below. a. Describe two specific biological processes that the cell could regulate in order to increase the amount of BiP protein. Briefly explain your answer using the information from figures A & B. A BİP MRNA expression BiP protein expression No unfolded Unfolded No unfolded Unfolded proteins in ER proteins in ER proteins in ER proteins in ER

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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When high levels of unfolded proteins are detected in the endoplasmic reticulum
(ER), a eukaryotic cell responds by increasing the gene expression of chaperone
proteins, which help proteins to fold correctly.
BiP is a chaperone protein. You detect amounts of BiP mRNA and protein in the
absence and presence of unfolded protein in the ER of a eukaryotic cell as shown in
the figure below.
a. Describe two specific biological processes that the cell could regulate in order to
increase the amount of BiP protein. Briefly explain your answer using the
information from figures A & B.
A
BİP MRNA expression
BiP protein expression
No unfolded
Unfolded
No unfolded
Unfolded
proteins in ER
proteins in ER
proteins in ER
proteins in ER
Transcribed Image Text:When high levels of unfolded proteins are detected in the endoplasmic reticulum (ER), a eukaryotic cell responds by increasing the gene expression of chaperone proteins, which help proteins to fold correctly. BiP is a chaperone protein. You detect amounts of BiP mRNA and protein in the absence and presence of unfolded protein in the ER of a eukaryotic cell as shown in the figure below. a. Describe two specific biological processes that the cell could regulate in order to increase the amount of BiP protein. Briefly explain your answer using the information from figures A & B. A BİP MRNA expression BiP protein expression No unfolded Unfolded No unfolded Unfolded proteins in ER proteins in ER proteins in ER proteins in ER
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