Q: Distinguish between proto-oncogenes and tumorsuppressor genes.
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Q: Which of the following statements about tumor suppressor genes is FALSE? a) Inactivation of tumor…
A: False statement about tumor suppressor genes.
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Q: Distinguish between proto-oncogenes and tumor suppressor genes?
A: The proto-oncogenes are those genes, which promote the cell cycle and inhibit apoptosis of the…
Q: What is the difference between an oncogene and a tumor-suppressor gene? Give some examples of the…
A: Cell proliferation, cell differentiation, and cell survival are under the control of some critical…
Q: The p53 gene encodes a tumor-suppressor protein, p53, which acts as a transcription factor for…
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Q: The TP53 gene provides instructions for making a protein called tumor protein p53. Known as the…
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Q: Describe three popular methods for silencing tumor-suppressor genes.
A: Introduction Tumor suppressor genes are those that slow down the division and development of cells.…
Q: Compare and contrast oncogenes and tumor suppressor genes.
A: Oncogenes are those genes that have the potential to cause cancer. These genes are often mutated or…
Q: The normal copies of tumor-suppressor genes encode proteins that have which three types of…
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Q: Describe how mutations in genome maintenance factors promote tumorigenesis. Why would inactivation…
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Q: Distinguish between proto-oncogenes and tumor-suppressor genes. To become cancer promoting, do…
A: Oncogene is a type of gene having the ability which can develop a cell to a tumor cell when…
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Q: Mutations in proto-oncogenes that turn them into oncogenes tend to be dominant, while cancer-causing…
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Q: Define oncogene, proto-oncogene, and tumor-suppressor gene.
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Q: Classify the following genes as proto-oncogenes or tumor-suppressor genes: p53, ras, Bcl-2,…
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Q: Explain in general what is meant by a proto-oncogene and how they are involved in the formation of a…
A: Proto-oncogenes are a bunch of normal genes present in a cell. They have the necessary information…
Q: What is the difference between a proto-oncogene and a tumor suppressor gene? How can mutations in…
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Q: Why don’t all loss-of-function mutations that are recessive at the cellular level behave as…
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Q: There are three broad categories of cancer-related genes: proto-oncogenes, tumor suppressor genes,…
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Q: Apart from p53, mention and describe the function of three tumor suppressor genes you know
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Q: Explain how epigenetic changes can contribute to tumorigenesis.
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Q: Compare and contrast oncogenes versus tumor-suppressorgenes.
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Q: How do BRCA1 and BRCA2 function in regard to cell proliferation (are they proto-oncogenes,…
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Q: Explain Mutations in tumor-suppressor genes are recessive at the cellular level but dominant at the…
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Q: Cellular levels of tumor suppressor protein p53 is maintained by a ubiquitin ligase protein, called…
A: From the above information, we can make the following inferences - 1. p53, as indicated in the…
Q: The diagram shows the relative activity of a proto-oncogene and a tumor supressor gene in a normal…
A: Proto oncogene: The gene that is important for normal cell growth. Mutations in these proto…
Q: Mutations in the ras gene family induce normal cells to proceed into the replication cycle. This…
A: Proto-oncogene normal function is to promote cell survival and cell division. Gain of function of…
Q: What are the key steps of transformation, tumorigenesis and metastasis on a cellular and tissue…
A: Transformation is a process in which a normal cell is transform into a cancerous cell Tumor genesis…
Q: Explain the difference between a proto-oncogene and a tumor-suppressor gene.
A: Cancer is the state of uncontrolled cell division.
Q: what are the rolls that the p53 gene and RAS protein take on when trying to stop a cancer cell from…
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What is the difference between an oncogene and a tumor-suppressor
gene? Give two examples of each type of gene.
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- What is a tumor suppressor? What is an oncogene?Which of the following is true of tumor suppressor genes? Group of answer choices a) If this gene is overactive, it becomes an oncogene b) If one of the alleles is mutated, there is usually little effect. Two inactivating mutations are usually required for loss of function (recessive mutation). c) If one copy is lost, the gene no longer functions (dominant mutation) d) Tumor suppressors genes usually cause mitosis or cell growth e) Tumor suppressor genes decrease apoptosisWhat is the difference between an oncogene and a tumor-suppressor gene? Give some examples of the functions of proto-oncogenes and tumor-suppressor genes in normal cells.
- D) The level of carbon dioxide increases with the level of available oxygen. 60) The TP53 gene provides instructions for making a protein called tumor protein p53. Known as the guardian of the genome, this protein acts as a tumor suppressor, which means that it regulates cell division by keeping cells from growing and dividing too fast or in an uncontrolled way. The p53 protein is located in the nucleus of cells throughout the body, where it attaches directly to DNA and plays a critical role in determining whether the DNA will be repaired or the damaged cell will self- destruct (undergo apoptosis). If the DNA can be repaired, p53 activates other genes to fix the damage. If the DNA cannot be repaired, this protein prevents the cell from dividing and signals it to undergo apoptosis. eg Suppose chromosomes in a skin cell are damaged by ultraviolet radiation. If the damaged genes do not affect p53, which choice correctly predict if the cell will become cancerous and why? No, the cell will…D) The level of carbon dioxide increases with the level of available oxygen. 60) The TPS3 gene provides instructions for making a protein called tumor protein p53. Known as the guardlan of the genome, this protein acts as a tumor suppressor, which means that it regulates cell division by keeping cells from growing and dividing t0o fast or in an uncontrolled way. The p53 protein is located in the nucleus of cells throughout the body, where it attaches directly to DNA and plays a critical role in determining whether the DNA will be repaired or the damaged cell will self- destruct (undergo apoptosis). If the DNA can be repaired, p53 activates other genes to fix the damage. If the DNA cannot be repaired, this protein prevents the cell from dividing and signals it to undergo apoptosis. Suppose chromosomes in a skin cell are damaged by ultraviolet radiation. If the damaged genes do not affect p53, which choice correctly predict if the cell will become cancerous and why? No, the cell will not…Define oncogene, proto-oncogene, and tumor-suppressor gene.
- Distinguish between proto-oncogenes and tumor-suppressor genes. To become cancer promoting, do proto-oncogenes and tumor-suppressor genes undergo gain-of-function or loss-of-function mutations? Classify the following genes as proto-oncogenes or tumor-suppressor genes: p53, ras, BCL-2, JUN, MDM2, and p16.Which of the following statements correctly describes a characteristic of tumor-suppressor gene? a) they are frequently overexpressed in cancerous cells. b) they are cancer-causing genes introduced into cells by viruses. c) they encode proteins that help prevent uncontrolled cell growth. d) they often encode proteins that stimulate the cell cycle.What are the major differences between a tumor initiator (e.g., DMBA) and a tumor promoting agent (e.g., TPA)?
- What is the difference in an oncogene and tumor suppressor gene and how can each potentially lead to cancer?Define tumor-suppressor genes. Why is a mutation in a single copy of a tumor-suppressor gene expected to behave as a recessive gene?The Bcl-2 protein was initially discovered via its ability to contribute to progression of B-cells to a cancerous "lymphoma" phenotype. 1) Define the mutation that was associated with the change in Bcl-2 in these cells. 2) Is Bcl-2 an oncogene or a tumor suppressor gene? 3) Define the role of Bcl-2 in normal cellular function and how this changed in Bcl-2 associated lymphoma.