TRUE OR FALSE 1. In the structure of Aztreonam, addition of a moiety capable of Van de Waals interaction confers stability against beta-lactamases 2. Addition of an acyl amino group to carbapenems increases their resistance to acid degradation, thus, making them stable in an oral dosage form 3. In the core structure of monobactams, the methyl group cannot be rotated because of its attachment on the beta lactam ring. The structure is too rigid for the methyl group to be rotated

TRUE OR FALSE 1. In the structure of Aztreonam, addition of a moiety capable of Van de Waals interaction confers stability against beta-lactamases 2. Addition of an acyl amino group to carbapenems increases their resistance to acid degradation, thus, making them stable in an oral dosage form 3. In the core structure of monobactams, the methyl group cannot be rotated because of its attachment on the beta lactam ring. The structure is too rigid for the methyl group to be rotated

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter31: Completing The Protein Life Cycle: Folding, Processing, And Degradation

Section: Chapter Questions

Problem 15P

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