the coding strand of DNA has the same sequence as the mRNA, except that there are U’s in the mRNA where there are T’s in the DNA.  The first triplet of nucleotides AAU (underlined) is in frame for coding, and encodes Asparagine.      45              50              55               60             65              5’—A A C G A A U C G U C G C C A A C U A A G A G  –-3’     Which of the following DNA mutations is almost certain to result in a shorter than normal protein?

Essentials Health Info Management Principles/Practices
4th Edition
ISBN:9780357191651
Author:Bowie
Publisher:Bowie
Chapter10: Introduction To Coding And Reimbursement
Section10.1: Clinical Classification Systems
Problem 5E
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A mRNA sequence is shown below.  Note that the coding strand of DNA has the same sequence as the mRNA, except that there are U’s in the mRNA where there are T’s in the DNA.  The first triplet of nucleotides AAU (underlined) is in frame for coding, and encodes Asparagine.

     45              50              55               60             65             

5’—A A C G A A U C G U C G C C A A C U A A G A G  –-3’   

 Which of the following DNA mutations is almost certain to result in a shorter than normal protein?  

 

   

at position 56 a change from G to C

   

an insertion of a G after the G at position 56

   

inversion of region 56-59 (G C C A)

   

an delete the C at position 52

   

None of the above.

Second letter
Phe UCU
UC
UGU
UGC
UUU
UAU
UAC Tyr
UAA Stop UGA
UAG Stop UGG
Cys
UUC
Ser
Stop A
Trp G
UUA
UCA
Leu
UUG
UCG
CU
CC
CUU
CAU
CGU
U
His
CỤC
CÁC
CGC
Leu
CUA
Pro
Arg
CCA
CAA
CGA
CUG
CCG
CAG Gin
CGG
G
AAU
AGU
Asn
AUU
ACU
Ser
AAC
AGC
AUC
A
AUA
lle
ACC
Thr
ACA
Met ACG
AAA
AGA
G Lys AGG
Arg
AUG
AAG
G
GUU
GCU
GAU
GGU
GUC
GCC
GAĆ
Asp
GGC
G
GUA
Val
GCA
Ala
GAA
Gly
GGA
Glu
GUG
GCG
GAG/
GGG
G
**
First letter
Third letter
Transcribed Image Text:Second letter Phe UCU UC UGU UGC UUU UAU UAC Tyr UAA Stop UGA UAG Stop UGG Cys UUC Ser Stop A Trp G UUA UCA Leu UUG UCG CU CC CUU CAU CGU U His CỤC CÁC CGC Leu CUA Pro Arg CCA CAA CGA CUG CCG CAG Gin CGG G AAU AGU Asn AUU ACU Ser AAC AGC AUC A AUA lle ACC Thr ACA Met ACG AAA AGA G Lys AGG Arg AUG AAG G GUU GCU GAU GGU GUC GCC GAĆ Asp GGC G GUA Val GCA Ala GAA Gly GGA Glu GUG GCG GAG/ GGG G ** First letter Third letter
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