Question 19 Listen If one puts the enhancer of a gene normally expressed in skin cells next to the coding sequence of a gene normally expressed in brain cells one would expect that the resulting mRNA Would be expressed in both brain and skin Would be expressed in the skin Would be expressed in the brain Would be expressed in neither brain nor skin

Question 19 Listen If one puts the enhancer of a gene normally expressed in skin cells next to the coding sequence of a gene normally expressed in brain cells one would expect that the resulting mRNA Would be expressed in both brain and skin Would be expressed in the skin Would be expressed in the brain Would be expressed in neither brain nor skin

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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QUESTION 12 Small nuclear RNAS (SNRNAS) regulate gene transcription O MRNA transport into the cytoplasm MRNA 3' cleavage MRNA translation and stability O splicing of mRNA precursors
QUESTION 7 SR proteins bind to splicing enhancers and activate splicing by recruiting spliceosome components. Mutations that affect SR proteins will have what kind of effect on gene expression? General transcription factors will be unable to bind to promoters. Splicing of the MRNA will not be activated. Ribosomes will not be able to bind to mRNA molecules in the cytoplasm. Polyadenylation at the 3' end will be blocked. RNA polymerase will be unable to terminate transcription. O0000
QUESTION 10 The steady state level of a MRNA for a gene is affected by the following mechanism(s) O Rate of RNA synthesis O The levels of nonsense suppressing TRNAS Rates of RNA synthesis and degradation Rate of RNA degradation O Frequency of AUG codons
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Question 25 Enhancer and activator proteins are working together O Gene is switched ON O Gene is switched OFF O Does NOT affect the gene expression
QUESTION 13 Transcriptional enhancers are: O A. operator sequences that repress transcription by blocking RNA polymerase initiation. O B. binding sites for general transcription factors. OC. binding sites for catabolite activating protein (CAP). O D. promoter-proximal regulatory sequences that recruit TATA-binding protein (TBP). O E. regulatory sequences that activate transcription from distant cis-linked promoters.
QUESTION 12 The leucine zipper domain of transcription factors is not involved in DNA recognition but rather in facilitating dimerization. Given the chemical properties of the amino acid leucine, dimerization of transcription factors via this domain by (select the correct option). Facilitating hydrogen bonding with the aqueous environment. Chelation of bivalent ions such as Zn2+. Formation of coiled-coils through hydrophobic non-covalent interactions between evenly spaced Leu residues in alpha-helical domains. Physically connecting the two transcription factor subunits through unstructured loops.
Question 19 Cells undergoing viral infection upregulate the expression of the stress molecules MIC-A and MIC-B. One evasion strategy adopted by Hepatitis B virus is to interfere with upregulation of these stress molecules by infected cells. This is advantageous to the virus because: O MIC-A and MIC-B are recognized by inhibitory receptors on NK cells NK cells upregulate activating receptors O MIC-A and MIC-B are recognized by KIR receptors on NK cells O Killing by NK cells is inhibited. O NK cells perceive lack of MIC-A/MIC-B as missing-self
QUESTION 7 You are trying to use qPCR to compare gene expression of nitrous oxide reductase (nosZ) in a Pseudomonas sample treated under various conditions. Using the 2-delta deltact method, about how much higher (or lower) is the expression of nitrous oxide reductase (nosZ) in the experimentally treated sample verses the untreated sample? nosZ Ct values for untreated sample (control conditions) Internal housekeeping nosz Ct values for Internal housekeeping gene Ct values for untreated sample (control conditions) gene Ct values for treatment sample experimental treatment sample experimental Replicate 1 21.3 20.0 19.8 20.9 Replicate 2 21.5 20.1 19.7 21.0 Replicate 3 21.4 20.3 19.5 20.7 Replicate 4 21.6 20.2 19.4 21.1 O A. -2 times higher B. -100 times higher C. about 20% as much as the control O D.-3.5 times higher O E. -12 times higher O F. -6 times higher than the control
Question 14 One of the two genes known to be mutated in cases of Hypokalemic periodic paralysis (which is inherited in an autosomal dominant pattern but known to affect males more often than females) is the calcium voltage-gated channel subunit alpha1 S (CACNA1S). What is known about the gene is recorded here: https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000081248;r=1:201039512-201112451 Please navigate to the link above. Use the left-hand menu to view the sequence for CACNA1S, and answer the following question. ANSWER ONLY IN UPPERCASE LETTERS, NO UNITS. What are the last six nucleic acid bases of exon 1? Answer: The last six nucleic acid bases of CACNA1S, exon 1 are Blank ...
Question 35 According to the reading "Pallidin and the Spread of Cancer," the protein encoded by the pallidin gene normally functions as O an activator of cell division, which can be turned off at the appropriate times during the cell cycle O a cytoskeletal protein, helping the cell maintain its shape O a tumor-suppressor protein, helping to stop the cell from dividing when DNA damage is present O a DNA repair enzyme which is activated by the presence of pyrimidine dimers
Question 26 The initial event in the conversion of an hnRNA to the mature RNA which leaves the nucleus is: A transesterification reactions in lariat formation. B splicing together of the exons. © addition of a poly(A) tail to the 3'-end of the transcript by poly(A) polymerase. D) capping the 5'-end of the transcript with a guanylyl group