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- . a. A mouse cross A/a ⋅ B/b × a/a ⋅ b/b is made, and inthe progeny there are25% A/a ⋅ B/b, 25% a/a ⋅ b/b,25% A/a ⋅ b/b, 25% a/a ⋅ B/bExplain these proportions with the aid of simplifiedmeiosis diagrams.b. A mouse cross C/c ⋅ D/d × c/c ⋅ d/d is made, and inthe progeny there are45% C/c ⋅ d/d, 45% c/c ⋅ D/d,5% c/c ⋅ d/d, 5% C/c ⋅ D/dExplain these proportions with the aid of simplifiedmeiosis diagrams.3. When Mendel cross- fertilised tall purple-flowered pea plants with short white-flowered pea plan and grew the resulting seeds. All the F1 generation were tall with purple flowers. a) Draw a genetic diagram to show the genotypes and phenotypes of the F1 generation b) Construct a punnett square to predict the outcomes of the phenotypes produced if the F1 generation were allowed to self fertilise. What is the phenotypic ratio?3) A. How are the following proteins involved in cell division: condensing, cohesin, kinetochore complex, tubulin? B. Why does phenotype not always reveal genotype? C. How can Mendel's postulates of segregation and independent assortment be explained by meiosis? D. Explain the genotypic and phenotypic ratios predicted when performing a monohybrid and a dihybrid cross of heterozygotes? E. How can you use the product rule and sum rule to calculate the probability of a particular genotype resulting from crossing parents of specific genotypes?
- The text outlines some of the problems Frederick William I encountered in his attempt to breed tall Potsdam Guards. a. Why were the results he obtained so different from those obtained by Mendel with short and tall pea plants? b. Why were most of the children shorter than their tall parents?What is probability, and how is it applied in genetic analysis?1. The allele G for yellow stigma is completely dominant to green (g). Supposingtwo strains of autotetraploid plants are available and their genotypes are as follows:GGgg – in this plant the gene is close to the centromereGggg – in this plant the gene is far from the centromere If these two plants are crossed:a) provide the gametes that can be obtained from the two plants;b) provide the genotypic and phenotypic ratios of the offspring. 2. Consider the illustration below. Diagram the configuration you would observe at Anaphase I if crossing-over happens within the inversion. (IMAGE ATTACHED)
- 3)Mendel found that crossing wrinkle-seeded (rr) plants with homozygous round-seeded(RR) plants produced only round-seeded plants. What genotype ratio and phenotyperatio can be expected from a cross between a wrinkle-seeded plant and a heterozygousplant for this characteristic?E. W. Lindstrom crossed two corn plants with green seedlings and obtained the following progeny: 3583 green seedlings, 853 virescentwhite seedlings, and 260 yellow seedlings (E. W. Lindstrom. 1921. Genetics 6:91–110). a. Give the genotypes for the green, virescent-white, and yellow progeny. b. Explain how color is determined in these seedlings. c. Is there epistasis among the genes that determine color in the corn seedlings? If so, which gene is epistatic and which is hypostatic?1. A heterozygous mouse AAy does not produce enough pigment and it is yellow. Homozygous individuals die during development, but AAy heterozygous do not. Why? You may use any graphic aid to explain this, if necessary. This means that you may use a Punnett square or a forking segregation diagram, or computations with fractions. 2. Explain why there is a non-Mendelian 2:1 yellow/agouti phenotypic ratio in this cross. 3. What is the Raly gene? What does it encode? How does it relate to the lethality of Ay?
- II. Solve the following problems. 1. Mendel crossed a plant that was heterozygous for height and heterozygous for pea shape with a plant that was homozygous dominant for height and heterozygous for shape. What are the possible genotypes and phenotypes of the offspring? Dominant for height= T (tall) Recessive for height =t (short) Dominant for pea shape = R (round) pea %3D Recessive for pea shape =r(wrinkled) P1: Genotypes: Phenotypes: Genotypic Ratio: Phenotypic Ratio9. Make a pedigree for each of the following situations. For each individual, write the individual's genotype (when possible) next to the individual's symbol (e.g. O xty, I Gg): a. Two parents do not have cystic fibrosis and they have a daughter with cystic fibrosis and a son who does not have cystic fibrosis. The daughter grows up and she mates with a male who does not have cystic fibrosis. Their only child is a boy and he has cystic fibrosis. b. A man with hemophilia mates with a female without hemophilia. They have one son and one daughter. The daughter has hemophilia and the son does not have hemophilia. The son grows up, and he marries and mates with a female. Their only child is a boy, and he has hemophilia.Shown are F₂ results of a monohybrid cross performed by Mendel. a) Calculate the expected numbers of each type of pods. Full pods Constricted pods Total 882 298 1180 0.84 b) What do these p-values mean with regards to your null hypothesis? (Please choose either reject or fail to reject.)
