1. A heterozygous mouse AAy does not produce enough pigment and it is yellow. Homozygous individuals die during development, but AAy heterozygous do not. Why? You may use any graphic aid to explain this, if necessary. This means that you may use a Punnett square or a forking segregation diagram, or computations with fractions. 2. Explain why there is a non-Mendelian 2:1 yellow/agouti phenotypic ratio in this cross. 3. What is the Raly gene? What does it encode? How does it relate to the lethality of Ay?
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1. A heterozygous mouse AAy does not produce enough pigment and it is yellow. Homozygous individuals die during development, but AAy heterozygous do not. Why? You may use any graphic aid to explain this, if necessary. This means that you may use a Punnett square or a forking segregation diagram, or computations with fractions.
2. Explain why there is a non-Mendelian 2:1 yellow/agouti
3. What is the Raly gene? What does it encode? How does it relate to the lethality of Ay?
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- Prediction If your hypothesis is correct, what will be the predicted ratio of phenotypes in your F, generation? (Punnett square may be used to explain) etv O MacBook Pro 三) 14 @ & 1 2 3 4 6 8. 9 Q W E R T Y P A J K く > C V option command command この つ エ のom either a 15-day-old 1-old guinea pig. Data from the Experiment When you have multiple sets of data, it can be useful to plot them on the same graph for comparison. In the graph here, each set of dots (of the same color) forms a scatter plot, in which every data point represents two numerical values, one for each variable. For each data set, a curve that best fits the points has been drawn to make it easier to see the trends. (For additional information about graphs, see the Scientific Skills Review in Appendix F.) INTERPRET THE DATA 1. First make sure you understand the parts of the graph. (a) Which variable is the independent variable-the variable controlled by the researchers? (b) Which variable is the dependent variable-the variable that depended on the treatment and was measured by the researchers? (c) What do the red dots represent? (d) The blue dots? 2. From the data points on the graph, construct a table of the data. Put "Incubation Time (min)" in the left column of the…Information Since dominance and recessiveness have intricate biochemical explanations, the only way of determining dominance is to cross two individuals that are homozygous (pure) for the two different phenotypes. This produces the heterozygous condition. Whichever phenotype is exclusively expressed is said to be the dominant phenotype. 1. A homozygous blue-eyed mouse with short whiskers mates with a homozygous brown-eyed mouse with long whiskers. All of their offspring have brown eyes and short whiskers. Which alleles are dominant? ? QUESTION 2. A homozygous five-clawed cat is crossed with a homozygous six- clawed cat and all of the kittens have six claws. Which allele is dominant? Dominant 3. In humans, the five-fingered condition is recessive to the six-fingered condition. Yet, most people have five fingers. Explain how this can happen. pes not mean frequent.
- Correct answers already provided! Please don't just tell me the answers bc I know them already. Help me with my own question. I get everything else in this problem other than the third option: Introduce the mutant human HD allele as a transgene into the mouse genome with transgene integration anywhere in the mouse genome. Why is the first question (left) okay with introducing mutant human HD allele and the second question (right) is not? I heard that introducing allele without using CRISPR-Cas9 is very rare and difficult. If so, how does it work in the first problem (Hungtinton's chorea)?Doctor Kryskowski: The autosomal dominant mode of inheritance and symptoms found in the patients from this family indicate that they suffer from Marfan syndrome. It is an inherited disorder caused by mutations in the FBN1 gene. What is the most feasible (easiest, cheapest, most reliable) way to investigate if this is the correct diagnosis?Could someone please help me with this grade 11 bio dihybrid cross problem on how to solve this question, using a strategy in detail! Assume that curly hair (C) is dominant to straight hair. Albinism (P ) is recessive to normal skin pigmentation. A woman who is heterozygous for curly hair and albinism has a child. The father is homozygous dominant for curly hair and has albinism. (a) Determine the possible phenotypes for their child. (double-crossing, Punnet square) (how to display the traits) (b) Calculate the four different probabilities of a child beingboth a male and of each phenotype. (steps in solving this) (c) What is the probability that the child will expressalbinism and have curly hair like his father? (steps in solving this)
- Variations in Phenotype Expression A genetic disorder characterized by falling asleep in genetics lectures is known to be 20% penetrant. All 90 students in a genetics class are homozygous for this gene. Theoretically, how many of the 90 students will fall asleep during the next lecture?"How to Solve Genetic Problems" Using Letters for Alleles For convenience, the genes of an allele pair are usually symbolized by a letter from the alphabet. A large letter is used for the dominant trait and a small letter for the recessive trait. When we want to describe the genotype of an organism, we use both letters to represent the alleles inherited from the parents. For example, free earlobes is a dominant allele and attached earlobes is recessive. You would use a capital "F" to indicate the dominant allele and a small “f" to indicate the recessive allele in describing an individual. 1. Write the three genotypes for earlobe attachment as it applies to the following individuals. a. Heterozygous b. Homozygous Dominant c. Homozygous Recessive 2. When it comes to symbolizing incomplete dominance with letters, it is best to use the letter "C" for one allele and "C'" for the other allele. List the three possible genotypes for hair type. a. Curly b. Wavy c. Straight. Why not use a small…he Sequence below comes from the alpha-2 globin of the human hemoglobin gene cluster found in chromosome 16. The globin region of the hemoglobin protein itself consists of 2 alpha chains and 2 beta chains. 1 actcttctgg tccccacaga ctcagagaga acccaccatg gtgctgtctc ctgccgacaa 61 gaccaacgtc aaggccgcct ggggtaaggt cggcgcgcac gctggcgagt atggtgcgga 121 ggccctggag aggatgttcc tgtccttccc caccaccaag acctacttcc cgcacttcga 181 cctgagccac ggctctgccc aggttaaggg ccacggcaag aaggtggccg acgcgctgac 241 caacgccgtg gcgcacgtgg acgacatgcc caacgcgctg tccgccctga gcgacctgca 301 cgcgcacaag cttcgggtgg acccggtcaa cttcaagctc ctaagccact gcctgctggt 361 gaccctggcc gcccacctcc ccgccgagtt cacccctgcg gtgcacgcct ccctggacaa 421 gttcctggct tctgtgagca ccgtgctgac ctccaaatac cgttaagctg gagcctcggt 481 agccgttcct cctgcccgct gggcctccca acgggccctc ctcccctcct tgcaccggcc 541 cttcctggtc…
- Based on standard MS- LS3-1: Fish in a cave system in Mexico is missing its eyes, has thin, translucent skin, and is relatively small (7-10 cm in length). Can you describe by model why structural changes to genes (mutations) on chromosomes may affect proteins and may result in beneficial effects to the structure and function of the fish? Can you answer in the following format? 1- Structure How Structure and Function is Affected by Mutations in Blind Fish Eyes Scales Taste Cells Lateral Line 2- Model to explain what causes these changes: Change: ______________ Adapting an Organism to the Dark Cause: ________________ Stop the Growth of Eyes Effect: ___________________ Fish with Heightened Other Senses References: Video: Rare Blind Cave Fish in Mexican Cave System https://www.youtube.com/watch?v=MWdtGuDd8z0 Fact Sheet: Blind Cave Fish https://www.denverzoo.org/animals/blind-cave-fish Information: Mexican Tetra…uh ec CV + + 10.5 SC 9.1 scute bristles echinus eyes 9.2 ct + crossveinless wings Table 1: phenotype wild-type tapdance feet crossveinless wings tapdance & crossveinless cut wings 15.9 vermilion eyes V + + 66.8 Drosophila X chromosome Use the map provided above for problems 1 & 2. Problem 1: 11.2 10.9 garnet eyes M A new gene is being investigated in fruit flies. The recessive allele of this gene (t) causes the flies' feet to grow tiny tapdance shoes, while the dominant allele (t*) permits wild-type feet to develop. Preliminary studies indicate that this new gene is located on the X-chromosome. You decided to perform a two-point testcross to determine its position relative to the well-established crossveinless wings gene (cv). You cross a female heterozygous for both genes with a testcross male fly and obtain the male offspring results shown in table 1, below. Using this information, answer the following questions: # male offspring 13 405 401 11 forked bristles a) is the original…THE MOLECULAR GENETICS OF SICKLE CELL ANEMIA The following is the base sequence of DNA that codes for first eight amino acids of the ß chain of hemoglobin. The ß chain of hemoglobin contains a total of 147 amino acids so this is a small part of the entire gene. mone formed DNA Template Strand: 3'CACGTGGACTGAGGACTCCTC5' 1. What is the minimum number of DNA nucleotides in this whole gene? 2. What is the sequence of bases on the strand of DNA that is complementary to the template strand? 4. What amino acids will this mRNA code for? 3. What mRNA will be formed from the template strand of DNA? 5. If the 17th base in the template strand of the DNA is changed from T to A, rewrite the new template strand below. 6. When the template strand of the DNA is changed, this is referred to as a mutation. What kind of mutation is this? 67