NH2 ད་ཡིན་ན། ༄ ོ་ད༥- ་ ཡི་ རྩ བྱིས་རྩ NH3 the acidity of the amine ion drives the reaction to shift toward the conjugate base of the carboxylic acid product. the resulting carboxylic acid ion is a weaker base than an acetate ion. O aldehydes are more reactive toward nucleophiles than ketones. nucleophilic attack occurs preferentially at the less hindered carbon of the formyl group.

NH2 ད་ཡིན་ན། ༄ ོ་ད༥- ་ ཡི་ རྩ བྱིས་རྩ NH3 the acidity of the amine ion drives the reaction to shift toward the conjugate base of the carboxylic acid product. the resulting carboxylic acid ion is a weaker base than an acetate ion. O aldehydes are more reactive toward nucleophiles than ketones. nucleophilic attack occurs preferentially at the less hindered carbon of the formyl group.

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter19: Aldehydes And Ketones: Nucleophilic Addition Reactions

Section19.SE: Something Extra

Problem 28VC

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