mechanisms of resistance to different xenobiotics (general groups of protection, efflux pumps, microorganisms, heavy metal resistance, resistance mechanisms in insects, a comparison of bacteria and insect resistance mechanisms, plant resistance mechanisms, animal resistance mechanisms
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Hello!!!
Discuss, with examples, the similarities and differences between mechanisms of resistance to different xenobiotics
(general groups of protection, efflux pumps, microorganisms, heavy metal resistance, resistance mechanisms in insects, a comparison of bacteria and insect resistance mechanisms, plant resistance mechanisms, animal resistance mechanisms).
thank you!!!!!
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- Give an brief explanation: A 69-year-old male is preparing to undergo a lung transplant. The transplantation laboratory is playing a major role in the preparations by consulting with the surgical team performing the transplant. 1. Members of the transplant team, including the transplantation laboratory, discuss the risk of graft-versus-host disease (GVHD) associated with lung transplantation. What is GVHD? A, Recipient T cells recognize foreign HLA antigens on donor cells, activating CD8 T cytotoxic cells. B. Recipient antigen-presenting cells receive processed donor HLA peptides from recipient HLA Class II molecules, which cause CD4 T helper cells to activate B cells to produce antibodies to foreign HLA molecules. C. Transplanted lymphocytes mount an immune response toward the recipient through T-cell destruction of host tissue. 2. Why does lung tissue have an increased risk of GVHD? A. Lung tissue is hard to properly match for ABO. B. Lung tissue contains an increased number of…Hello, I need help with the chemical structures of the following compounds in bold; thanks! Immunotherapy’s purpose is to boost the immune system. The following are the clinical medications currently in use: Ipilimumab, Nivolumab, Pembrolizumab. Targeted therapy purpose is to treat advanced melanoma. The following are the clinical medications currently in use: Vemurafenib, Dabrafenib, Trametinib.Which link in the chain of infection is the intervention described below meant to break? Having moderate-to-severe asthma may increase your risk for severe illness from COVID-19. Actions you take should include: Follow your Asthma Action Plan. Continue your current medicines, including any inhalers with steroids in them. Make sure that you have at least a 30-day supply of your medicines. Avoid your asthma triggers. (https://www.cdc.gov/coronavirus/2019- ncov/need-extra-precautions/people-with-medical-conditions.html) Means of transmission Infectious agent Susceptible host Portal of entry
- "out Document1 - Word References Mailings 1. Search Review View Help Answer the questions A) What is the most common anesthetic to use in animals for induction under anesthesia? B) What are the side effects of using Propofol in animals? C) How and with what will the animal be "scrubbed" after it is under anesthesia and ready for the doctor? D) What is the purpose of SPO2 and where is it put in the animal? E) What is the purpose of the ECG and where are they placed on the animal?76% , خميس 17 أيلول uo 10:58 Meet A docs.google.com 9- The success of the implant depends on d) None of above a) Application isometrically identical b) Cost c) Both a and b 10- Which one of the following is not correct? a) Biocompatibility is the ability of a material to perform within an appropriate host response. b) Bioactivity is the characteristic that not allows the material to form a bond with living tissue c) Biodegradability is the breakdown of the implant due to chemical or cellular interaction. d) all of above 11- Choose the best match that represents the implant -tissue in different classes of ceramics: (i) Biological fixation (ii) Degrades gradually and replaced by tissue; (iii) Attached by chemical bonds;. (iv) Chemical bond; (a) Type I- (i); Type II - (ii); Type III - (iii); Type IV - (iv) (b) Type I- (iv); Type II - (ii); Type III - (ii); Type IV - (i) (c) Type I - (iv); Type II - (i); Type III - (iii); Type IV - (ii) (d) Type I - (i); Type II (iv); Type III - (iii);…Write about Oxford–AstraZeneca COVID-19 vaccine (Covishield) You must include the following information Chemistry of the drugs: Structure, physicochemical properties, (log P, pKa, & stereochemistry) and chemical properties and stability. Mechanism of action: (including the possible drug target interactions) in CoVid-19 Pharmacokinetic: Absorption, distribution (% plasma binding), chemical basis of metabolic pathways and elimination Pharmacological properties including side effect, ADR, drug interaction, precautions, dose and dosage forms Stability and storage conditions, as well as Brand names
- A patient is starting -arfarin (Coumadin) therapy as part of treatment for atrial fibrillation. The nurse -ill follo- -hich principles of -arfarin therapy? (Select all that apply.) a )Teach proper subcutaneous administrationb )Administer the oral dose at the same time every dayc) Assess carefully for excessive bruising or unusual bleedingd )Monitor laboratory results for a target INR of 2 to 3e )Monitor laboratory results for a therapeutic aPTT value of 1.5 to 2.5 times the control valueThe production of antimicrobial peptides is one of the most evolutionarily ancient mechanisms of defense for multicellular organisms, and most eukaryotic species make many different forms of these proteins. For instance, human paneth cells in the gastrointestinal epithelium make 21 different defensins. The reason for this diversity of antimicrobial peptides is: Epithelial cells make different forms than those made by neutrophils. Neutrophils make many different defensins and store them as inactive proteins in their secretory granules. Most of them are produced only in response to infection. The production of different peptides is induced following a bacterial infection versus a fungal infection. Each one has distinct activities against Gram-negative bacteria, Gram-positive bacteria, or fungi.Semi-synthetic and extended-spectrum penicillins have proven more effective than natural penicillins for two of the following reasons: 1-Interfere more effectively with the development of the peptidoglycan layer in cell-walls 2-Are less sensitive to penicillinases than natural penicillins 3-Do not contain the b-lactam ring thus making them less susceptible to b-lactamases 4-Are less susceptible to the development of resistance 5-Have a broader spectrum of activity
- Pharmacodynamic (PD) Response Biomarkers Instructions Group (https://www.ncbi.nlm.nih.gov/books/NBK326791/), a biomarker is used to show that a biological response has occurred in an individual who has been exposed to a medical product or an environmental agent. Match the pharmacodynamic/response biomarker on the left, with the related you can use internet search, FDA According to the FDA-NIH Biomarker Working treatment/disease on the right. Please note that and NIH websites, as well as the on-line library resources. Sweat chloride Response to warfarin treatment International Effect of enzyme replacement therapy for patients with mucopolysaccharidosis type 1 normalized ratio (INR) Response to a B-lymphocyte stimulator inhibitor in patients with systemic lupus erythematosus Viral load Urinary level of glycosaminoglycans Response to cystic fibrosis transmembrane regulator (CFTR) potentiating agents in patients with cystic fibrosis Blood pressure Response to antihyperglycemic agents or…Discuss how drug hypersensitivity reactions can affect various organs. Include in your answer specific examples and address the underlying mechanisms.Home infusion: these are true, except: A) All patients can be home infusion patients B) Caregivers are educated about patients’ therapies C) All patients should be treated as if they were infectious D) Temperature control is critical during transport of meds