In the reaction of a nitrile with a Grignard reagent, there are two steps: a) nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the imine to form a ketone. Draw the intermediate and the final product in this reaction. Ignore inorganic byproducts. CH₂MgBr CH3O NO Edit Imine Ion Intermediate P
In the reaction of a nitrile with a Grignard reagent, there are two steps: a) nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the imine to form a ketone. Draw the intermediate and the final product in this reaction. Ignore inorganic byproducts. CH₂MgBr CH3O NO Edit Imine Ion Intermediate P
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter11: Ethers, Epoxides, And Sulfides
Section: Chapter Questions
Problem 11.42P
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Question
![In the reaction of a nitrile with a Grignard reagent, there are two
steps: a) nucleophilic addition of the Grignard to form an imine
ion and b) hydrolysis of the imine to form a ketone.
Draw the intermediate and the final product in this reaction.
Ignore inorganic byproducts.
N
CH3MgBr
CH3O
NO
Edit Imine Ion Intermediate
1. H₂O*
Q
Problem 25 c](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fa98d5f9f-2d8e-4b4a-a8bb-f7d23ac6808f%2F06db5b3d-e31d-4877-82d8-0737de84c328%2F5cd5zu5_processed.jpeg&w=3840&q=75)
Transcribed Image Text:In the reaction of a nitrile with a Grignard reagent, there are two
steps: a) nucleophilic addition of the Grignard to form an imine
ion and b) hydrolysis of the imine to form a ketone.
Draw the intermediate and the final product in this reaction.
Ignore inorganic byproducts.
N
CH3MgBr
CH3O
NO
Edit Imine Ion Intermediate
1. H₂O*
Q
Problem 25 c
![NO
Edit Imine Ion Intermediate
CH3O
CH3O
1. H3O+
2. Neutralizing work-up
Edit Final Product](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fa98d5f9f-2d8e-4b4a-a8bb-f7d23ac6808f%2F06db5b3d-e31d-4877-82d8-0737de84c328%2Fgrk8v6r_processed.jpeg&w=3840&q=75)
Transcribed Image Text:NO
Edit Imine Ion Intermediate
CH3O
CH3O
1. H3O+
2. Neutralizing work-up
Edit Final Product
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